Developing a Peer Support Intervention for Depression in SCD

Subjective Cognitive Decline Clinical Trial

Official title:

Developing a Peer Support Intervention for Depression in SCD

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT06358404
• Other study ID #: 2024P000615
• Status: Not yet recruiting
• Phase: N/A
• Start date: May 1, 2024
• Est. completion date: April 30, 2026

Study information

• Verified date: April 2024
• Source: Massachusetts General Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The purpose of this study is to assess the feasibility, acceptability, and fidelity of an 8-week intervention where peer coaches will deliver depression care to adults 60 years of age or older who have depression and subjective cognitive decline.

Description:

With support from the MADRC ORE Core, we will recruit 30 community-dwelling older adults to conduct an open pilot study of PeersCOG. Trained and supervised peer coaches will deliver depression care to adults 60 years of age and older with depression and subjective cognitive decline in an 8-week intervention using video chats and texts. We will use mixed methods to assess feasibility, acceptability, and fidelity. We will use validated instruments to assess the preliminary outcomes, including depression, SCD, functioning, and social factors at baseline, 8 weeks, and 3 months, and we will conduct post-intervention interviews with stakeholders at 8 weeks. Older adult participants will be asked to name a study partner who will support the older adult throughout the study in terms of study enrollment. They may also have additional perspectives on the impact of impaired cognition and depression on daily living and related needs. The older adult will not be excluded if the study partner is not available.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 30
• Est. completion date: April 30, 2026
• Est. primary completion date: April 30, 2026
• Accepts healthy volunteers: No
• Gender: All
• Age group: 60 Years and older

Eligibility

Inclusion Criteria:

• Older adults aged 60+
• Endorse subjective cognitive decline
• Endorse depressive symptoms
• not currently experiencing suicidal ideation nor active, untreated manic, psychotic, or substance use disorder
• fluent in English and able to give informed consent

Exclusion Criteria:

• Meets diagnostic criteria for mild cognitive impairment or Alzheimer's dementia
• Meets diagnostic criteria for a current major depressive disorder
• have a history of neurological and psychiatric comorbidities such as major depressive disorder in the past 12 months

Related Conditions & MeSH terms

• Cognitive Dysfunction
• Depression
• Depression in Old Age
• Depressive Disorder
• Subjective Cognitive Decline

Intervention

Behavioral:
• PeersCOG
. The intervention will consist of 8 weekly video chats focused on emotional, appraisal, and informational support delivered by community-based older adult peer coaches to adults 60 years of age and older with subthreshold depression and SCD.

Locations

Country	Name	City	State
n/a

Sponsors (2)

Lead Sponsor	Collaborator
Massachusetts General Hospital	National Institutes of Health (NIH)

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Feasibility of Intervention	Level of participant engagement: how many screened older adults agree to participate in the intervention and complete baseline assessments	Measured at baseline enrollment
Primary	Acceptability of Intervention	Number of meetings older adults complete with peer coach	Measured during intervention (8 weeks)
Primary	Fidelity of Intervention	Degree of adherence to intervention	Measured during intervention (8 weeks)