Subclinical Carotid Atherosclerosis Clinical Trial
Official title:
Early Detection of Subclinical Carotid Atherosclerosis Through Autonomic Testing
Background: Atherosclerotic carotid intima-media thickness (IMT) may be associated with
alterations in the sensitivity of carotid and subclavian baroreceptors.
Aim: The aim of this study is to investigate if carotid IMT is associated with changes in the
autonomic modulation of the heart rate variability (HRV).
Methods: This is a prospective cross-sectional study. The carotid IMT is determined by B-mode
and duplex ultrasonography. The cardiovagal function was determined through linear and
nonlinear measures of HRV. Linear regression models, adjusted for demographics,
comorbidities, body mass index, waist-hip-ratio, and left ventricular ejection fraction will
be used to evaluate the association between HRV parameters and carotid IMT.
n/a
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT01203982 -
Effect of Intensive Lipid Lowering Treatment Compared to Moderate Lipid Lowering Treatment on Carotid Intima-media Thickness (CIMT)
|
Phase 4 |