Graded Repetitive Arm Supplementary Program Versus Task Based Training on Upper Limb Function in Stroke Patients

Stroke Clinical Trial

Official title:

Effects of Graded Repetitive Arm Supplementary Program Versus Task Based Training on Upper Limb Function in Stroke Patients

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT06397170
• Other study ID #: REC/RCR & AHS/23/0281
• Status: Recruiting
• Phase: N/A
• Start date: May 1, 2024
• Est. completion date: September 15, 2024

Study information

• Verified date: June 2024
• Source: Riphah International University
• Contact: Zeest hashmi
• Phone: 03224655851
• Email: zeest.hashmi[@]riphah.edu.pk
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

To determine effects of graded repetitive arm supplementary program versus Task based training on Upper limb function in stroke patients.

Description:

This study will be Randomized Clinical Trial. A total of 38 stroke patients will be recruited by using non-probability convenience sampling Technique. Patients will be Randomized and allocated into two interventional groups based on the inclusion and exclusion criteria. Patients in Group A will receive Graded repetitive arm supplementary program and Patients in Group B will receive Task based training. All participants will receive the treatment for 40 minutes per session, 5 days per week for 5 weeks. For the evaluation of all participant scales like be Chedoke Arm and Hand Activity Inventory for clinical relevance, Fugl Mayer assessment scale for performance assessment, Action Reach Arm Test for coordination and dexterity and Motor Activity Log for functional assessment of Upper limb in stroke patients. D

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 38
• Est. completion date: September 15, 2024
• Est. primary completion date: September 1, 2024
• Accepts healthy volunteers: No
• Gender: All
• Age group: 40 Years to 60 Years

Eligibility

Inclusion Criteria:

• Patients with Sub acute stage of stroke.

• Patients with Ischemic and Haemorrhagic stroke.

• Patients with Cognition level on Mini Mental State Examination must be > 24

• Patients with mild pain in upper extremity according to Numeric Pain Rating Scale

• Patients with Grade 2 active movements in affected extremity Tone of upper limb at Modified Ashworth Scale Grade 1+.

Exclusion Criteria:

• Other neurological disorders e.g. brain tumor, encephalitis, meningitis, brain abscess.

• Use of antipsychotics

• Use of drugs for spasticity.

• Patients with vestibular impairment.

Related Conditions & MeSH terms

• Motor Activity
• Muscle Weakness
• Paresis
• Stroke
• Upper Extremity Paresis

Intervention

Other:
• Graded repetitive arm supplementary program
Patients in Group A will receive Graded repetitive arm supplementary program
• Task based training
Patients in Group B will receive Task based training.

Locations

Country	Name	City	State
Pakistan	Imran International Amjad	Islamabad	Punjab

Sponsors (1)

Lead Sponsor	Collaborator
Riphah International University

Country where clinical trial is conducted

Pakistan, 

References & Publications (4)

Connell LA, McMahon NE, Watkins CL, Eng JJ. Therapists' use of the Graded Repetitive Arm Supplementary Program (GRASP) intervention: a practice implementation survey study. Phys Ther. 2014 May;94(5):632-43. doi: 10.2522/ptj.20130240. Epub 2014 Feb 6. — View Citation

Lee HS, Lim JH, Jeon BH, Song CS. Non-immersive Virtual Reality Rehabilitation Applied to a Task-oriented Approach for Stroke Patients: A Randomized Controlled Trial. Restor Neurol Neurosci. 2020;38(2):165-172. doi: 10.3233/RNN-190975. — View Citation

Veerbeek JM, van Wegen E, van Peppen R, van der Wees PJ, Hendriks E, Rietberg M, Kwakkel G. What is the evidence for physical therapy poststroke? A systematic review and meta-analysis. PLoS One. 2014 Feb 4;9(2):e87987. doi: 10.1371/journal.pone.0087987. eCollection 2014. — View Citation

Yang CL, Waterson S, Eng JJ. Implementation and Evaluation of the Virtual Graded Repetitive Arm Supplementary Program (GRASP) for Individuals With Stroke During the COVID-19 Pandemic and Beyond. Phys Ther. 2021 Jun 1;101(6):pzab083. doi: 10.1093/ptj/pzab083. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Fugl Mayer assessment scale	It is designed to assess reflex activity, movement control and muscle strength in the upper extremity of people with post-stroke hemiplegia. total score is 126.This tool has an excellent Inter- and intrarater reliability (intra class correlation coefficient = 0.98-0.99), validity is also excellent (r = 0.74-0.93, P < .0001). Higher scores indicate maximum recovery	6 months
Primary	The Motor Activity Log (MAL)	The Motor Activity Log (MAL) is a subjective outcome measure of an individual's real life functional upper limb performance.The Motor activity log is administered by semi-structured interview and items are scored by patients according to their performance of each task over the past 7 days. The MAL adopts a 6-point ordinal scale, although patients can attribute a half-score, resulting in 11-point Likert scales with specified anchoring definitions at 6 points	6 months