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Neuromodulation Effect of Focused Ultrasound for Motor Recovery in Patients With Stroke

Stroke Clinical Trial

Official title:
Neuromodulation Effect of Focused Ultrasound for Motor Recovery in Patients With Stroke

Clinical Trial Summary

Transcranial focused ultrasound (tFUS) can be used as a non-invasive brain neuromodulation technique. Low-intensity focused ultrasound has been demonstrated to be safe and have neuromodulatory effects on the cerebral cortex in healthy human and animal experiments.This study aims to investigate the effect of tFUS on cortical excitability for motor recovery in patients with stroke.

Clinical Trial Description

The study is a pilot study for feasibility, which aims to recruit 20 patients with subacute (within 3 months) stroke and unilateral hemiparesis. tFUS stimulation will be delivered. The primary outcomes are defined as cortical excitability assessment in bilateral primary motor cortex, as well as safety analysis; the secondary outcome measures include the Fugl-Meyer Assessment, Medical Research Council score, National Institutes of Health Stroke Scale (NIHSS), Barthel Index, Modified Rankin Scale and functional brain activities. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06391086
Study type Interventional
Source National Taiwan University Hospital
Contact Meng Ting Lin, M.D.
Phone +886-2312-3456
Email b96401093@ntu.edu.tw
Status Not yet recruiting
Phase N/A
Start date June 1, 2024
Completion date October 1, 2029
View Details
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