Clinical Trial Details
— Status: Recruiting
Administrative data
| NCT number |
NCT06362954 |
| Other study ID # |
AnkaraMedipolU-FTR-SS-01 |
| Secondary ID |
|
| Status |
Recruiting |
| Phase |
|
| First received |
|
| Last updated |
|
| Start date |
December 31, 2023 |
| Est. completion date |
June 1, 2024 |
Study information
| Verified date |
April 2024 |
| Source |
Ankara Medipol University |
| Contact |
n/a |
| Is FDA regulated |
No |
| Health authority |
|
| Study type |
Observational
|
Clinical Trial Summary
Conditions such as hemiparesis, sensory and motor impairment, perceptual impairment,
cognitive impairment, aphasia, and dysphagia may be observed after stroke. Motor impairment
after stroke may occur due to damage to any part of the brain related to motor control. There
is much clinical evidence that damage to different parts of the sensorimotor cortex in humans
affects other aspects of motor function. Loss of strength, spasticity, limb apraxia, loss of
voluntary movements, Babinski sign, and motor neglect are typical motor deficits following a
cortical lesion (upper motor neuron lesion). Post-stroke spasticity can be seen in 19% to 92%
of stroke survivors. Post-stroke hemiparesis is a significant cause of morbidity and
disability, along with abnormal muscle tone. It has also been recognized that post-stroke
hemiparesis may occur without spasticity. Spasticity seen after stroke causes loss of
movement control, painful spasms, abnormal posture, increased muscle tone, and a general
decrease in muscle function, and may affect limb blood flow. Studies in the literature show
that spasticity can affect limb blood flow.
This study aims to investigate the relationship between muscle oxygenation and spasticity in
post-stroke hemiparetic patients based on the idea that oxygenation may be insufficient as a
result of restriction of blood flow on the affected side due to spasticity in stroke
patients.
Description:
Conditions such as hemiparesis, sensory and motor impairment, perceptual impairment,
cognitive impairment, aphasia, and dysphagia may be observed after stroke. Motor impairment
after stroke may occur due to damage to any part of the brain related to motor control. There
is much clinical evidence that damage to different parts of the sensorimotor cortex in humans
affects other aspects of motor function. Loss of strength, spasticity, limb apraxia, loss of
voluntary movements, Babinski sign, and motor neglect are typical motor deficits following a
cortical lesion (upper motor neuron lesion). Post-stroke spasticity can be seen in 19% to 92%
of stroke survivors. Post-stroke hemiparesis is a significant cause of morbidity and
disability, along with abnormal muscle tone. It has also been recognized that post-stroke
hemiparesis may occur without spasticity. Spasticity seen after stroke causes loss of
movement control, painful spasms, abnormal posture, increased muscle tone, and a general
decrease in muscle function, and may affect limb blood flow. Studies in the literature show
that spasticity can affect limb blood flow.
Motor deficits seen in stroke patients and the conditions caused by them cause various
limitations in the daily life of patients and affect their participation in daily life and
quality of life. Decreased involvement in daily life negatively affects patients both
socially and financially. Evaluating and identifying the disorders, taking preventive and
developmental measures, and establishing treatment programs are necessary to increase
participation. Therefore, objective and accurate assessment significantly affects the
progress of the process.
Medical and surgical treatment and physiotherapy and rehabilitation approaches constitute the
basis of treatment in stroke disease. The treatment of patients is carried out using a
multidisciplinary approach involving many fields, such as medical and surgical treatment,
physiotherapy, and rehabilitation practices. For this reason, it is seen that the financial
burden, which cannot be covered by the insurance system from time to time, is relatively
high. This burden is gradually increasing in direct proportion to the needs of the patients.
For this reason, it is essential to develop practices and strategies for the patient's
objective and most accurate evaluation, follow the clinical course, and create the most
appropriate treatment program.
Although it is not among the routine evaluation methods, considering the studies conducted,
"muscle oxygenation" should be considered in the evaluation phase in line with the
possibilities.
