Stroke Clinical Trial
— Stroke_DynUSOfficial title:
Het Gebruik Van Dynamische Echografie om Spier-pees Veranderingen te Onderzoeken in de Kuitspieren Van Personen na Een CVA: Een Pilootstudie
Verified date | June 2024 |
Source | University Hospital, Ghent |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
Muscle behaviour of calf muscles can be studied during dynamic conditions using dynamic ultrasound. In particular, the medial gastrocnemius is suitable for measurements with dynamic ultrasound due to its superficial location. With this measurement technique, the muscle behavior during walking can be observed gaining insight into the mechanism of action of this muscle during a functional task. This technique has already been used in other populations (such as children with cerebral palsy) but not yet in individuals after a stroke. Therefore, the aim of this study is to assess the muscle behavior of the medial gastrocnemius during walking in persons after stroke. There are 3 concrete objectives of the current study: 1. is the technique feasible to perform in persons after stroke? 2. does the use of the dynamic echoprobe change gait patterns? 3. can differences between persons after stroke and healthy controls be detected? This data can be used as pilot data for project applications in the future that will allow to design larger studies. Therefore, 10 stroke patients and 10 age- and gender-matched healthy controls will walk on a treadmill for 3x2 minutes after a familiarisation period of 6 minutes. During 1 x 2 minutes, subjects will walk without using the dynamic ultrasound. This recording aims to measure the normal gait pattern of the subjects. During the other 2x2 minutes, subjects will walk using the dynamic ultrasound at 2 different locations on the calf. Once with the ultrasound probe on the centre of the muscle belly to visualise muscle fibre bundles and once on the muscle tendon transition, from which muscle belly and tendon length can be derived. The use of ultrasound or not will be randomized to exclude the effect of fatigue on the outcome measures.
Status | Completed |
Enrollment | 13 |
Est. completion date | April 4, 2024 |
Est. primary completion date | April 4, 2024 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years to 65 Years |
Eligibility | Stroke group Inclusion criteria - stroke adults - no other neurologic conditions - ability to walk independently on a treadmill Exclusion criteria - wearing ankle foot orthosis that inhibit the assessment - had lower limb surgery in the past Healthy volunteers Inclusion criteria - healthy adults Exclusion criteria - suffering from any neurological condition - had lower limb surgery in the past |
Country | Name | City | State |
---|---|---|---|
Belgium | Ghent University Hospital | Ghent |
Lead Sponsor | Collaborator |
---|---|
University Hospital, Ghent | University Ghent |
Belgium,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Fascicle dynamics measured with ultrasound during walking | Lengthening and shortening of the fascicles of the medial gastrocnemius | single point assessment in one day during walking with the probe | |
Primary | Muscle belly dynamics measured with ultrasound during walking | Lengthening and shortening of the muscle belly of the medial gastrocnemius | single point assessment in one day during walking with the probe | |
Primary | Tendon dynamics measured with ultrasound during walking | Lengthening and shortening of the tendon of the medial gastrocnemius | single point assessment in one day during walking with the probe | |
Secondary | gait speed | walking velocity (m/s) | single point assessment in one day during walking with the probe | |
Secondary | gait speed | walking velocity (m/s) | single point assessment in one day during walking without the probe | |
Secondary | step width | step width (m) | single point assessment in one day during walking with the probe | |
Secondary | step width | step width (m) | single point assessment in one day during walking without the probe | |
Secondary | Step length | Step length (m) of the paretic and non paretic side | single point assessment in one day during walking with the probe | |
Secondary | Step length | Step length (m) of the paretic and non paretic side | single point assessment in one day during walking without the probe | |
Secondary | stance phase | time spend standing on the paretic and non-paretic leg (s) during walking | single point assessment in one day during walking with the probe | |
Secondary | stance phase | time spend standing on the paretic and non-paretic leg (s) during walking | single point assessment in one day during walking without the probe | |
Secondary | swing phase | time spend not standing on the paretic and non-paretic leg (s) during walking | single point assessment in one day during walking with the probe | |
Secondary | swing phase | time spend not standing on the paretic and non-paretic leg (s) during walking | single point assessment in one day during walking without the probe | |
Secondary | lower limb kinematics | joint angles (°) in the pelvis, hip, knee and ankle in the sagittal, frontal and transverse plane during walking | single point assessment in one day during walking with the probe | |
Secondary | lower limb kinematics | joint angles (°) in the pelvis, hip, knee and ankle in the sagittal, frontal and transverse plane during walking | single point assessment in one day during walking without the probe |
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