Effect of Agonist Contract Relax Versus Antagonist Contract Relax in Chronic Stroke Patient.

Stroke Clinical Trial

Official title:

Effect of Agonist Contract Relax Versus Antagonist Contract Relax Technique on Spasticity and Ankle Range of Motion in Chronic Stroke Patient.

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05957731
• Other study ID #: REC-UOL-246-04-2023
• Status: Completed
• Phase: N/A
• Start date: November 7, 2022
• Est. completion date: July 30, 2023

Study information

• Verified date: August 2023
• Source: University of Lahore
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

It will be a randomized control trial with 112 patients which will be divided into two groups of 56 patients in each group. Participants will recruit through convenient sampling techniques.

Outcome measures are range of motion and spasticity. The protocol was implemented three days per week for eight consecutive weeks. Data will be collected at baseline and 8 th week after intervention.

Description:

Objective of the study is to compare the effects of the agonist contract-relax technique versus the antagonist contract-relax technique on spasticity and range of motion in individuals with chronic stroke.

Null hypothesis (H0):

There are no comparative effects of agonist contact-relax technique and the antagonist contract-relax technique on spasticity and ankle range of motion in chronic patients.

The alternate hypothesis (HA):

There are comparative effects of agonist contract-relax technique and the antagonist contract-relax technique on spasticity and ankle range of motion in chronic stroke patients.

The sample size came out to 94 (47 in each group) after adding 20% dropout the sample size was 47+9=56 in each group.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 112
• Est. completion date: July 30, 2023
• Est. primary completion date: July 30, 2023
• Accepts healthy volunteers: No
• Gender: All
• Age group: 40 Years to 60 Years

Eligibility

Inclusion Criteria:

• Patients with a confirmed diagnosis of stroke by a neurologist.

• Inclusion of patients with both ischemic and hemorrhagic stroke.

• Both male and female patients are eligible.

• Age range between 40 to 60 years.

• Modified Ashworth Scale ranging from 0 to 2.

• Minimum muscle strength grade of 3

Exclusion Criteria:

• History of surgery on lower limb

• Who received injection therapies for reducing spasticity

• Lower extremity contracture

• Modified Ashworth scale of 3-4

Related Conditions & MeSH terms

• Stroke

Intervention

Other:
• Routine physical therapy
Both groups received routine physical therapy, which encompasses various components such as electrotherapy, strength training for both lower and upper limbs, gait training, and occupational therapy.
• antagonist contract relax
antagonist contraction i used to improve spasticity and range of motion in stroke patients
• agonist contract relax
agonist contraction is used to improve spasticity and range of motion in stroke patients

Locations

Country	Name	City	State
Pakistan	sir Ganga Raam hospital lahore	Lahore
Pakistan	univerity of Lahore teaching hopital	Lahore

Sponsors (1)

Lead Sponsor	Collaborator
University of Lahore

Country where clinical trial is conducted

Pakistan, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Modified Ashworth Scale.	The assessment involves extending the limb of the parent from a state of utmost flexion to utmost extension, identifying the point at which initial mild resistance was encountered. Following that, the modified Ashworth Scale is employed while transitioning the limb from extension to flexion. Interrater reliability studies utilizing the MAS have yielded varied results, ranging from moderate to good.	it will measure change in spasticity at baseline and at 8th week
Primary	universal goniometer	The universal goniometer (UG) is a widely employed tool for assessing range of motion.Range of motion refers to the complete extent of movement possible at a specific joint. In a normal ankle, the range of motion typically spans from around 20ºof dorsiflexion to 50º of plantar flexion. For normal walking, a combined motion of approximately 24º to 30º (including both dorsiflexion and plantar flexion) is required.	it will measure change in range of motion at baseline and at 8th week