Stroke Clinical Trial
Official title:
Comparative Efficacy of Different Time Interval Between rTMS and Rehabilitation Program for Motor Recovery in Stroke Patients
Comparative Efficacy of Different Time Interval between rTMS and Rehabilitation Program for Motor Recovery in Stroke Patients
Status | Not yet recruiting |
Enrollment | 45 |
Est. completion date | December 2024 |
Est. primary completion date | December 2024 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 20 Years and older |
Eligibility | Inclusion criteria 1. >=20 years old, unilateral stroke diagnosed by CT or MRI 2. Post-stroke 1 week to 6 months 3. Medical Research Council Scale for Muscle Strength in upper limb = 3 4. No history of previous stroke, seizure, dementia, parkinsonism or other neurodegenerative disease 5. stable medical condition and vital signs Exclusion criteria 1. Previous stroke, traumatic brain injury, brain tumor 2. With central nervous system disease (spinal cord injury, Parkinson's disease) 3. Any contraindication to rTMS (seizure, alcoholism, metal implant, pacemaker, Pregnancy...) 4. Patients unable to cooperate the treatment |
Country | Name | City | State |
---|---|---|---|
Taiwan | National Taiwan University Hospital Hsin-Chu Branch | Hsinchu |
Lead Sponsor | Collaborator |
---|---|
National Taiwan University Hospital Hsin-Chu Branch |
Taiwan,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Fugl-Meyer Assessment (FMA) | Fugl-Meyer Assessment (FMA) of upper limb | 12 weeks | |
Secondary | Medical Research Council (MRC) scale | Medical Research Council (MRC) scale | 12 weeks | |
Secondary | Grip strength | Grip strength (Kg) | 12 weeks | |
Secondary | Barthel Index | Barthel Index | 12 weeks | |
Secondary | Modified Rankin Scale | Modified Rankin Scale | 12 weeks | |
Secondary | maximal motor evoked potential amplitude | maximal motor evoked potential amplitude of lesion site (mV) | 12 weeks | |
Secondary | motor evoked potential latency | motor evoked potential latency of lesion site (ms) | 12 weeks | |
Secondary | resting motor threshold | bilateral resting motor threshold (mV) | 12 weeks |
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