Stroke Clinical Trial
Official title:
Comparing Different Montages of Transcranial Direct Current Stimulation Combined With Dual-task Training on EEG Microstates A Proof-of-concept Study
This study investigates whether electroencephalographic (EEG) measures of functional connectivity of the target network are associated with the response to different sets of transcranial direct current stimulation combined with dual-task training in post-stroke patients.
Status | Recruiting |
Enrollment | 10 |
Est. completion date | December 30, 2023 |
Est. primary completion date | December 30, 2023 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years and older |
Eligibility | Inclusion Criteria: - Post-stroke participants for more than 6 months - Individuals over 18 years of age; - Both sexes; - Patients with mild to moderate degree of injury severity (NIHHS <17 points) Exclusion Criteria: - Patients with other associated pathologies that can influence motor activity (example: traumatic brain injury, brain tumor); - Habitual use of drugs or alcohol; - Use of drugs that modulate the activity of the Central Nervous System; - Gestation; - Use of metallic / electronic implants and / or cardiac pacemakers; - Participants unable to communicate verbally; |
Country | Name | City | State |
---|---|---|---|
Brazil | Federal University of Paraíba,Department of Psychology | João Pessoa | Paraiba |
Lead Sponsor | Collaborator |
---|---|
Federal University of Paraíba |
Brazil,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Microstates EEG | EEG data were processed according to the following steps and parameters: (1) downsampled to 256 Hz; (2) high-pass filter at 2 Hz and low-pass at 20 Hz; (3) visual inspection and artifact removal; (4) correction of eye movement using the independent component analysis; and (5) segmentation into two-second epochs with 10% overlap. The choice for the 2-20 Hz range frequency band. Data were submitted to processing: determination of global field power; clustering using k-means of topographic maps of global field power peaks; determination of the optimal number of topographic maps using a predetermined criterion of the four classic maps (A, B, C, and D); application of the topographic maps to the EEG signal using spatial correlation; and classification of EEG continuous data according to the topographic map with the most correlated sections. We calculated and extracted the global explained variance, coverage, occurrence, and duration from each topography. | The evaluations will be carried out in pre-intervention | |
Primary | Functional connectivity | EEG data were processed according to the following steps and parameters: (1) downsampled to 256 Hz; (2) high-pass filter at 2 Hz and low-pass at 20 Hz; (3) visual inspection and artifact removal; (4) correction of eye movement using the independent component analysis; and (5) segmentation into two-second epochs with 10% overlap. The choice for the 2-20 Hz range frequency band. Data were submitted to processing: determination of global field power; clustering using k-means of topographic maps of global field power peaks; determination of the optimal number of topographic maps using a predetermined criterion of the four classic maps (A, B, C, and D); application of the topographic maps to the EEG signal using spatial correlation; and classification of EEG continuous data according to the topographic map with the most correlated sections. We calculated and extracted the global explained variance, coverage, occurrence, and duration from each topography. | Immediately after the intervention | |
Secondary | Timed up and Go test | Timed up and Go test | The evaluations will be carried out in pre-intervention | |
Secondary | Timed up and Go test | Timed up and Go test | Immediately after the intervention | |
Secondary | Executive Functions I | Trial-making Test A and B | The evaluations will be carried out in pre-intervention | |
Secondary | Executive Functions I | Trial-making Test A and B | Immediately after the intervention | |
Secondary | Executive Functions II | the Clock Drawing Test | The evaluations will be carried out in pre-intervention | |
Secondary | Executive Functions II | the Clock Drawing Test | Immediately after the intervention | |
Secondary | Executive Functions III | Phonemic Verbal Fluency Test | The evaluations will be carried out in pre-intervention | |
Secondary | Executive Functions III | Phonemic Verbal Fluency Test | Immediately after the intervention |
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