Stroke Clinical Trial
Official title:
Perception of Electrical Stimuli During Muscle Activation in Individuals With Stroke
Verified date | January 2024 |
Source | Northwestern University |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
To successfully manipulate objects in one's surroundings, such as when lifting a cup, one must accurately perceive their physical interactions. This includes accurately interpreting the tactile cues arising at one's fingertips when touching an object. Currently, tactile perception is assessed in individuals with stroke using passive protocols. Research has yet to explore whether activating one's muscles impacts the tactile perceptual process in individuals with stroke despite previous research demonstrating the effect of muscle activation on tactile perception in individuals who are neurologically intact. The proposed research will be the first to address the impact of muscle activation, in addition to stroke, on tactile perception. As such, the proposed research is significant for advancing our understanding of the extent to which tactile deficits occur in individuals with stroke, particularly during volitional movement.
Status | Enrolling by invitation |
Enrollment | 45 |
Est. completion date | March 2025 |
Est. primary completion date | March 2025 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years and older |
Eligibility | Inclusion Criteria: - For the participants with stroke, i) a single unilateral cortical lesion that took place at least one year prior and ii) an absence of comorbid neurological impairments - Ability to understand and complete the experimental tasks - Capacity to provide informed consent - At least 18 years of age Exclusion Criteria: - Major injury to either arm - Sensory neuropathy |
Country | Name | City | State |
---|---|---|---|
United States | Northwestern University Physical Therapy and Human Movement Sciences | Chicago | Illinois |
Lead Sponsor | Collaborator |
---|---|
Netta Gurari | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), Northwestern University |
United States,
Chapman, C. E., Zompa, I. C., Williams, S. R., Shenasa, J. & Jiang, W. Factors influencing the perception of tactile stimuli during movement. in Somesthesis and the Neurobiology of the Somatosensory Cortex (eds. Franzén, O., Johansson, R. & Terenius, L.) 307-320 (Birkhäuser Basel, 1996).
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Pavlenko, V. B. Self-initiated motor behavioral act-related neuronal activity in the cat Locus Coeruleus. Neurophysiology 35, 29-37 (2003).
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Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Detection threshold | Minimum magnitude of current at which an electrical stimulus can be detected | ~5 minutes |
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