Stroke Clinical Trial
Official title:
Effects of Neurodynamics on Lower Extremity Spasticity - a Study in Chronic Stroke
Verified date | October 2021 |
Source | National Yang Ming University |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
Post-stroke spasticity in the lower extremity affects balance and gait, leading to decreased mobility and functional independence. Therefore, effective intervention for reducing spasticity is crucial in stroke rehabilitation. Recently, neurodynamics, though originally designed for pain management in orthopedic patients, has also been applied for treating spasticity in patients with neurological disorders. However, previous studies focused mainly on treating the upper extremity spasticity, but not on lower extremity spasticity, and not on possible neurophysiological changes. The present study aims to investigate the immediate effects of neurodynamics in reducing lower limb spasticity and neurophysiological changes in people with chronic stroke.
Status | Completed |
Enrollment | 15 |
Est. completion date | January 26, 2022 |
Est. primary completion date | January 26, 2022 |
Accepts healthy volunteers | No |
Gender | All |
Age group | N/A and older |
Eligibility | Inclusion Criteria: - diagnosis of first-ever stroke with unilateral lesion for more than 6 months - demonstrating calf muscle spasticity as indicated by modified Ashworth scale equal to or greater than 1 - with passive ROM of ankle dorsiflexion at least to neutral position (defined as 0°) - ability to walk at least 10m independently without a walking device or ankle-foot orthosis (AFO) - sufficient cognition (mini-mental state examination, MMSE score of 24 or higher) Exclusion Criteria: - contraindications to nerve conduction tests - other orthopedic and neurological disorders interfering participating in the study |
Country | Name | City | State |
---|---|---|---|
Taiwan | National Yang Ming Chiao Tung University | Taipei |
Lead Sponsor | Collaborator |
---|---|
National Yang Ming University |
Taiwan,
Cha HK, Cho HS, Choi JD. Effects of the nerve mobilization technique on lower limb function in patients with poststroke hemiparesis. J Phys Ther Sci. 2014 Jul;26(7):981-3. doi: 10.1589/jpts.26.981. Epub 2014 Jul 30. — View Citation
Datta Gupta A, Visvanathan R, Cameron I, Koblar SA, Howell S, Wilson D. Efficacy of botulinum toxin in modifying spasticity to improve walking and quality of life in post-stroke lower limb spasticity - a randomized double-blind placebo controlled study. BMC Neurol. 2019 May 11;19(1):96. doi: 10.1186/s12883-019-1325-3. — View Citation
López López L, Torres JR, Rubio AO, Torres Sánchez I, Cabrera Martos I, Valenza MC. Effects of neurodynamic treatment on hamstrings flexibility: A systematic review and meta-analysis. Phys Ther Sport. 2019 Nov;40:244-250. doi: 10.1016/j.ptsp.2019.10.005. Epub 2019 Oct 15. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Change in Spasticity: Clinical measurement | The modified Ashworth scale (MAS) will be used, which is a 6-point scale commonly used to assess muscle spasticity in clinical settings. | Before intervention and immediately after intervention | |
Primary | Change in Spasticity: Neurophysiological measurement | The H-reflex will be recorded by placing a disposable surface electrode on the muscle belly of the gastrocnemius after a stimulation of the tibial nerve just proximal to the electrode. | Before intervention and immediately after intervention | |
Secondary | Change in Gait Performance | Gait performance will be measured by using the GAITRite system (CIR system, Inc., Havertown, Pennsylvania). Participants will be instructed to walk along the walkway at their comfortable speed. Gait velocity, cadence, and step length of the affected and unaffected limbs, and spatial and temporal asymmetry ratios are calculated. | Before intervention and immediately after intervention | |
Secondary | Change in Lower Extremity Motor Control | Motor control of the lower extremity will be assessed by the motor section of the Fugl-Meyer Assessment (FMA). Higher scores represent better motor control, with a total score of 34. | Before intervention and immediately after intervention |
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