Clinical Trials Logo

Clinical Trial Summary

This study is being done to see how errors lead to improvement. Specifically, we are evaluating the errors stroke participants make during an upper extremity exercise program when reaching for a target using their affected arm. Once we understand the participant's reaching errors, we plan to create a customized reaching exercise according to the individual's specific error tendencies which will lead to better performance on movement ability after training.


Clinical Trial Description

The neuroplasticity of motor re-learning is a key pathway for recovery in neurorehabilitation. One critical challenge to devising treatment plans for motor recovery is the wide variation that exists between individuals, across movement repetitions, and even within movements. Development of a learning model that looks at these factors would better relate diagnoses to treatments, providing personalization and efficiency to therapy. This proposal aims to advance rehabilitation by building a modeling framework that explores the trends and exploits a fundamental learning process - error. We are using research lab equipment at the Shirley Ryan AbilityLab (SRALab) Hospital's Robotics group. The equipment will be used to implement the reaching exercises and measure participant movement. The equipment includes: 1. Barret b.u.r.t. arm robot with Teneo forearm attachment 2. LookinGlass display system 3. LeapTM Sensor tracking tool Day 1: Participants will undergo a screening and consenting session with a research therapist to assess enrollment eligibility. Day2: If the participant meets all inclusion/exclusion criteria, they will return and complete a series of upper extremity outcome measures to characterize impairment level. Day 3 and 4: The participant will then complete 1-2 intervention sessions using the Barret b.u.r.t. arm, LookinGlass display screen, and LeapTM tracking sensor. This intervention study will last anywhere from 15-min-90 min depending the equipment functioning. The intervention will consist of two phases: 1. Learning Phase to determine the individual's error likelihood 2. Training Phase to apply determined error likelihood to see if there are any changes in performance Our goal is to preliminarily test the direct effect of this new treatment in preparation for the randomized controlled study to come. Understanding how error leads to better performance will help us program future devices for therapy for optimal outcomes. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05180786
Study type Interventional
Source Shirley Ryan AbilityLab
Contact Courtney Celian
Phone 3122381560
Email [email protected]
Status Not yet recruiting
Phase Phase 1
Start date February 21, 2022
Completion date December 30, 2022

See also
  Status Clinical Trial Phase
Recruiting NCT04043052 - Mobile Technologies and Post-stroke Depression N/A
Recruiting NCT04101695 - Hemodynamic Response of Anodal Transcranial Direct Current Stimulation Over the Cerebellar Hemisphere in Healthy Subjects N/A
Suspended NCT03869138 - Alternative Therapies for Improving Physical Function in Individuals With Stroke N/A
Completed NCT04034069 - Effects of Priming Intermittent Theta Burst Stimulation on Upper Limb Motor Recovery After Stroke: A Randomized Controlled Trial N/A
Terminated NCT03052712 - Validation and Standardization of a Battery Evaluation of the Socio-emotional Functions in Various Neurological Pathologies N/A
Completed NCT00391378 - Cerebral Lesions and Outcome After Cardiac Surgery (CLOCS) N/A
Recruiting NCT04535479 - Dry Needling for Spasticity in Stroke N/A
Recruiting NCT03985761 - Utilizing Gaming Mechanics to Optimize Telerehabilitation Adherence in Persons With Stroke N/A
Recruiting NCT00859885 - International PFO Consortium N/A
Recruiting NCT03622411 - Tablet-based Aphasia Therapy in the Chronic Phase N/A
Completed NCT01662960 - Visual Feedback Therapy for Treating Individuals With Hemiparesis Following Stroke N/A
Recruiting NCT03366129 - Blood-Brain Barrier Disruption in People With White Matter Hyperintensities Who Have Had a Stroke
Recruiting NCT03281590 - Stroke and Cerebrovascular Diseases Registry
Completed NCT04399759 - Instrumental Activities of Daily Living Approach in Home Environment for Patients With Stroke N/A
Completed NCT03698357 - Video Balance-based Exercise in Persons With Stroke N/A
Active, not recruiting NCT04069039 - Is There a Relationship Between the Ability of the Trunk and Lower Extremities and Walking Function After Stroke?
Completed NCT03578536 - Effect of Constraint-Induced Gaming Therapy in an Acute Care Setting N/A
Recruiting NCT03605381 - MORbidity PRevalence Estimate In StrokE
Active, not recruiting NCT03402906 - Family-Clinician Collaboration to Improve Neglect and Rehabilitation Outcome After Stroke N/A
Completed NCT02907775 - Multi-channel Stimulation for Post Stroke Spasticity (MUSTS) N/A