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Effect of Proximal Blood Flow Arrest During Endovascular Thrombectomy — ProFATE  

Stroke Clinical Trial

Official title:
Effect of Proximal Blood Flow Arrest During Endovascular Thrombectomy

Clinical Trial Summary

Endovascular thrombectomy (EVT) has become the standard of care for large vessel occlusion in acute ischaemic stroke (AIS). During clot-retrieval, simultaneous balloon inflation within the internal carotid artery offers transient proximal blood flow arrest, potentially preventing distal clot migration or embolisation to new vascular territories. Retrospective studies indicate that this may improve complete vessel recanalisation rates and may translate to improved functional independence. However, lack of high-quality evidence demonstrating the efficacy of simultaneous balloon inflation has led to clinical equipoise with heterogeneity of practice globally.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05020795
Study type Interventional
Source Nottingham University Hospitals NHS Trust
Contact Permesh Singh Dhillon
Phone 01159249924
Email permesh.dhillon@nhs.net
Status Recruiting
Phase N/A
Start date October 7, 2021
Completion date December 1, 2023
View Details
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