Stroke Survival in Municipalities: Impact of Geographic Proximity to First- and Second-degree Relatives

Stroke Clinical Trial

Official title:

Stroke Survival in Municipalities: Impact of Geographic Proximity to First- and Second-degree Relatives

Clinical Trial Details — Status: Active, not recruiting

Administrative data

• NCT number: NCT04072120
• Other study ID #: NorStrokeSurvival
• Status: Active, not recruiting
• Start date: August 15, 2019
• Est. completion date: August 14, 2022

Study information

• Verified date: May 2020
• Source: University of Oslo
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Our key objective will be to investigate if geographic proximity to first- and second-degree relatives has an influence on post-acute stroke survival and use of health and social services. We will also model and map spatial variation in stroke and cardiovascular disease (CVD) incidence and mortality and see if some of the variation is due to spatial clustering of familial risk. The study will use innovative approaches to large-scale registry and survey data and statistical analysis on the full Norwegian population. We will integrate multigenerational and geographical information. This will enable us to assess key determinants on stroke survival and use of health and social care at municipality level.

Recruitment information / eligibility

• Status: Active, not recruiting
• Enrollment: 7400000
• Est. completion date: August 14, 2022
• Est. primary completion date: August 14, 2022
• Accepts healthy volunteers: No
• Gender: All
• Age group: 45 Years and older

Eligibility

Inclusion Criteria:

• Norwegian citizens aged 45 and above 1.1.1994 - 31.12. 2009 and had stroke events

• Those who attend a cardiovascular health survey who later developed stroke.

• All Norwegians born in the period 1 January 1940 to 31 December 1959 who survived to 1991

• Norwegian citizens aged 45 and above 1.1.2016 and had stroke events

Exclusion Criteria:

-

Related Conditions & MeSH terms

• Stroke

Locations

Country	Name	City	State
Norway	Department of Community Medicine and Global Health,University of Oslo	Oslo

Sponsors (3)

Lead Sponsor	Collaborator
University of Oslo	Extrastiftelsen, Nasjonalforeningen for folkehelsen

Country where clinical trial is conducted

Norway, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	R1- Mortality	Mortality of Norwegian citizens aged 45 and above 1.1.1994 - 31.12. 2009	Mortality follow-up from 1.1.1994 to 31.12.2014
Primary	R2- Mortality	Mortality of all Norwegians born in the period 1 January 1940 to 31 December 1959 who survived to 1991	Mortality follow-up from 1991-2014.
Primary	R3- Stroke events	Norwegian citizens aged 45 and above 1.1.2016	Stroke events registered in the Patient registry after 2016, (possibly until 2019)