The Effects of Whole Body Vibration in People With Chronic Stroke

Stroke Clinical Trial

Official title:

The Effects of Whole Body Vibration Training With Different Frequencies on Bone Health and Neuromotor Performance in Individuals With Chronic Stroke: A Randomized Controlled Trial.

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03982251
• Other study ID #: HSEARS20140226001-03
• Status: Completed
• Phase: N/A
• Start date: June 28, 2017
• Est. completion date: August 28, 2018

Study information

• Verified date: June 2019
• Source: The Hong Kong Polytechnic University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Whole body vibration (WBV) has been found to be useful in promoting bone health and muscle performance in older adults. To date, no study has examined the effects of different WBV frequencies on the properties of the muscle-bone unit in stroke patients. The overall aim of the proposed study is to compare the efficacy of different vibration frequencies on properties of the muscle function and bone turnover among people with chronic stroke.

It is hypothesized that the higher-vibration frequency protocol will lead to significantly better outcomes related to the bone turnover and muscle function.

Description:

Whole body vibration (WBV) has been found to be useful in promoting bone health and muscle performance in older adults. To date, no study has examined the effects of different WBV frequencies on the properties of the muscle-bone unit in stroke patients. The overall aim of the proposed study is to compare the efficacy of different vibration frequencies on properties of the muscle function and bone turnover among people with chronic stroke.

It is hypothesized that the higher-vibration frequency protocol will lead to significantly better outcomes related to the bone turnover and muscle function in people with chronic stroke.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 80
• Est. completion date: August 28, 2018
• Est. primary completion date: June 28, 2018
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

1. a diagnosis of stroke

2. stroke onset >6 months

3. >18 years of age

4. able to walk for short distance independently with or without walking aid

5. able to understand simple verbal commands

Exclusion Criteria:

1. neurological conditions other than stroke

2. significant musculoskeletal conditions (e.g. amputations)

3. metal implants in the lower extremity

4. previous fracture of the lower extremity

5. are currently taking bone resorption inhibitors or were taking the same before stroke.

6. significant peripheral vascular disease

7. vestibular disorders

8. pregnancy

9. Other serious illnesses that preclude the person from participating in the study

Related Conditions & MeSH terms

• Stroke

Intervention

Procedure:
• High frequency whole body vibration
1 single session ( 8 minutes) of whole body vibration therapy at 30 Hz
• Low frequency whole body vibration
1 single session ( 12 minutes) of whole body vibration therapy at 20 Hz

Locations

Country	Name	City	State
Hong Kong	The Hong Kong Polytechnic University	Hongkong

Sponsors (1)

Lead Sponsor	Collaborator
The Hong Kong Polytechnic University

Country where clinical trial is conducted

Hong Kong, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	bone resorption marker	Serum level of aminoterminal crosslinked telopeptide	pre-test (week 0)
Primary	bone resorption marker	Serum level of aminoterminal crosslinked telopeptide	post-test (week8)
Secondary	Six Minute Walk Test	endurance test	pre-test (week 0)
Secondary	Six Minute Walk Test	endurance Test	post-test (week8)
Secondary	Gait velocity	10-meter walking test	pre-test (week 0)
Secondary	Gait velocity	10-meter walking test	post-test (week8)
Secondary	Spasticity	H-reflex on tibial nerve and modified ashworth scale	pre-test (week 0)
Secondary	Spasticity	H-reflex on tibial nerve and modified ashworth scale	post-test (week8)