Stroke Clinical Trial
Official title:
Diagnosis by Comprehensive Cardiovascular Imaging for Stroke and Transient Ischaemic Attacks
Stroke affects over 125,000 people each year in the UK and leaves at least 50% disabled.
After a first stroke, there is a significant risk of recurrence (around 5-10% over the first
year). While there are benefits from addressing general risk factors such as exercise, weight
and smoking, selecting the best treatments for preventing a further stroke depends on
understanding the underlying mechanism. Most strokes results from a blood clot causing a
blockage in a blood vessel in the brain ("ischaemic" strokes, about 85% of cases). The clot
may originate in the heart, the major blood vessels supplying the head, or result from
disease of the small blood vessels in the brain itself (around 25% of cases each), and in
around 25% of people a cause cannot be determined (sometimes because more than one exists).
Different treatments are given depending on cause (for example, anticoagulant medication for
clots from the heart, surgery for some arising from large arteries in the neck).
Current investigations involve multiple tests spread across different hospital departments,
and commonly take several weeks to be completed. This may contribute to a high rate of
strokes of uncertain cause, and may delay the start of the best treatment.
This trial will investigate the value of a single comprehensive scan to look at the heart and
major blood vessels (using CT scanning) in a pilot study, comparing the classification of
causes of stroke and the time to starting treatments with routine care, in a randomised study
of patients with recent stroke or transient ischaemic attack (TIA, a short-lived stroke
episode).
n/a
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT04043052 -
Mobile Technologies and Post-stroke Depression
|
N/A | |
| Recruiting |
NCT03869138 -
Alternative Therapies for Improving Physical Function in Individuals With Stroke
|
N/A | |
| Completed |
NCT04034069 -
Effects of Priming Intermittent Theta Burst Stimulation on Upper Limb Motor Recovery After Stroke: A Randomized Controlled Trial
|
N/A | |
| Completed |
NCT04101695 -
Hemodynamic Response of Anodal Transcranial Direct Current Stimulation Over the Cerebellar Hemisphere in Healthy Subjects
|
N/A | |
| Terminated |
NCT03052712 -
Validation and Standardization of a Battery Evaluation of the Socio-emotional Functions in Various Neurological Pathologies
|
N/A | |
| Completed |
NCT00391378 -
Cerebral Lesions and Outcome After Cardiac Surgery (CLOCS)
|
N/A | |
| Recruiting |
NCT06204744 -
Home-based Arm and Hand Exercise Program for Stroke: A Multisite Trial
|
N/A | |
| Active, not recruiting |
NCT06043167 -
Clinimetric Application of FOUR Scale as in Treatment and Rehabilitation of Patients With Acute Cerebral Injury
|
||
| Active, not recruiting |
NCT04535479 -
Dry Needling for Spasticity in Stroke
|
N/A | |
| Completed |
NCT03985761 -
Utilizing Gaming Mechanics to Optimize Telerehabilitation Adherence in Persons With Stroke
|
N/A | |
| Recruiting |
NCT00859885 -
International PFO Consortium
|
N/A | |
| Recruiting |
NCT06034119 -
Effects of Voluntary Adjustments During Walking in Participants Post-stroke
|
N/A | |
| Completed |
NCT03622411 -
Tablet-based Aphasia Therapy in the Chronic Phase
|
N/A | |
| Completed |
NCT01662960 -
Visual Feedback Therapy for Treating Individuals With Hemiparesis Following Stroke
|
N/A | |
| Recruiting |
NCT05854485 -
Robot-Aided Assessment and Rehabilitation of Upper Extremity Function After Stroke
|
N/A | |
| Active, not recruiting |
NCT05520528 -
Impact of Group Participation on Adults With Aphasia
|
N/A | |
| Completed |
NCT03366129 -
Blood-Brain Barrier Disruption in People With White Matter Hyperintensities Who Have Had a Stroke
|
||
| Completed |
NCT03281590 -
Stroke and Cerebrovascular Diseases Registry
|
||
| Completed |
NCT05805748 -
Serious Game Therapy in Neglect Patients
|
N/A | |
| Recruiting |
NCT05993221 -
Deconstructing Post Stroke Hemiparesis
|