Upper Limb Function and Visuospatial Exploration After Stroke

Stroke Clinical Trial

Official title:

Assessing Pathological Synergies of Upper Limb Function and the Relationship to Visuospatial Exploration After Stroke

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03135093
• Other study ID #: 2016-02075
• Status: Completed
• Start date: April 1, 2017
• Est. completion date: December 30, 2019

Study information

• Verified date: January 2020
• Source: University of Zurich
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

This project is a cross-sectional, observational mono-center study with prospective data collecting.

This study aims to further explore quality of upper limb movement in relation to characteristics of visuospatial exploration in stroke subjects and healthy subjects by a applying comprehensive measurements of clinical scales and kinematic data in capacity- and performance-based activities. The results will contribute to assessing and monitoring quality of upper limb movements and visuospatial attention and their relationship.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 35
• Est. completion date: December 30, 2019
• Est. primary completion date: December 30, 2019
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Subjects of 18 years and older with chronic ischemic stroke (> 6 month) restricted to one hemisphere (confirmed by CT/MRI)

• With impairments in upper limb function and at least partial ability to lift the arm against gravity, flex and extend the fingers

• Without relevant pre-existing limitations in arm and hand function (orthopaedic, muscular, neurologic)

• Written informed consent after participants's information

Exclusion Criteria:

• Increased muscle tone in the upper limb with limited rang of motion

• Severe sensory deficits in the upper limb

• Clinically significant concomitant disease (affecting the upper limb or impaired vision, e.g. due to glaucoma etc.)

• Contraindications on ethical grounds (vulnerable persons)

• Known or suspected non-compliance, drug or alcohol abuse

• Severe communication or cognitive deficits, that cause inability to follow the procedures

Related Conditions & MeSH terms

• Stroke

Intervention

Other:
• No intervention
No Intervention

Locations

Country	Name	City	State
Switzerland	cereneo Schweiz AG	Vitznau	Luzern

Sponsors (1)

Lead Sponsor	Collaborator
University of Zurich

Country where clinical trial is conducted

Switzerland, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Upper limb movement quality	Fugl-Meyer Assessment of the upper extremity (FMA-UE), kinematic data (e.g. joint angles, hand workspace)	One day
Primary	Visuospatial exploration	Eye-tracking data (e.g. area of interest, eye movements: saccades, fixations) and to rule out stroke-related deficits of visuospatial attention, clinical tests	One day