Vitamin D and Stroke

Stroke Clinical Trial

Official title:

Vitamin D and Stroke: A Comparative Study to Risk Factors and Stroke Type

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02916030
• Other study ID #: IRB0000871535
• Status: Completed
• Start date: September 1, 2016
• Est. completion date: January 3, 2017

Study information

• Verified date: July 2018
• Source: Assiut University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Stroke remains one of the most devastating neurological diseases, often causing death, or gross physical impairment. It is the second most common cause of death worldwide and a major cause of acquired disability in adults.Vitamin D deficiency has been reported to contribute to the risk of cardiovascular disease especially stroke.

Description:

This case -control observational prospective study will conducted on fifty patients with first -ever acute onset stroke within seven days (25 patients with hemorrhagic stroke and 25 patients with ischemic stroke )

Recruitment information / eligibility

• Status: Completed
• Enrollment: 50
• Est. completion date: January 3, 2017
• Est. primary completion date: January 2, 2017
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 80 Years

Eligibility

Inclusion Criteria:

• Onset is within one week

• Confirmed stroke by brain CAT and / or MRI scan either haemorrhage or infarction

Exclusion Criteria:

• Cognitive and mental changes

• Recurrent stroke

• Hepatic and renal impairment

• Endocrinal diseases

• Steroid therapy

• Vitamin D or Ca supplementation

• Previous fractures

• Bone diseases

• brain neoplasm,

• Autoimmune diseases

• History of acute and chronic inflammatory diseases

• Malignancy,

• Trauma

• Surgery

• Acute vascular diseases that occurred within four weeks prior the onset of stroke

• History myocardial infarction ?3 months.

Related Conditions & MeSH terms

• Stroke

Intervention

Dietary Supplement:
• Vit D
It is to examine the relationship between serum 25 (OH) D levels and Stroke either ischemic or hemorrhagic types

Locations

Country	Name	City	State
Egypt	Faculty of Medicine	Assiut

Sponsors (1)

Lead Sponsor	Collaborator
Assiut University

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	serum 25 (OH) D levels	serum 25 (OH) D levels	Within the first 24 hours
Secondary	Stroke severity	Stroke severity will be assessed by Scandinavian Stroke scale Stroke (SSS)	Within the first 24 hours
Secondary	Stroke etiology		Within the first 24 hours
Secondary	Stroke risk factors		Within the first 24 hours
Secondary	Stroke subtypes		Within the first 24 hours