Cardiac MRI in Ischemic Stroke Study

Stroke Clinical Trial

— CaMriSS  

Official title:

Cardiac MRI in Ischemic Stroke Study

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01917955
• Other study ID #: CaMriSS_CSB
• Secondary ID: EA4/073/10
• Status: Completed
• Phase: N/A
• First received: August 7, 2012
• Last updated: November 7, 2016
• Start date: January 2012
• Est. completion date: November 2014

Study information

• Verified date: November 2016
• Source: Charite University, Berlin, Germany
• Contact: n/a
• Is FDA regulated: No
• Health authority: Germany: Ministry of Health
• Study type: Observational

Clinical Trial Summary

The purpose of this prospective single-center trial is to compare the safety and diagnostic value of contrast medium-enhanced cardiac magnetic resonance imaging and transesophageal echocardiography in patients with acute ischemic stroke.

Description:

Primary safety objective: Contrast medium-enhanced cardiac magnetic resonance imaging is safe in patients with acute ischemic stroke. Primary outcome: The diagnostic value of contrast medium-enhanced cardiac magnetic resonance imaging is comparable to transesophageal echocardiography in patients with acute ischemic stroke.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 103
• Est. completion date: November 2014
• Est. primary completion date: November 2014
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Patients with acute ischemic stroke detected by brain magnetic resonance imaging.

Exclusion Criteria:

• Known atrial fibrillation or cardiac source of embolism

• Severe aphasia

• Acute infection or chronic inflammation

• Severe arteriosclerosis or stenosis of brain-supplying arteries

• Contraindications for magnetic resonance imaging or transesophageal echocardiography.

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Related Conditions & MeSH terms

• Stroke

Locations

Country	Name	City	State
Germany	Charité, Universitätsmedizin Berlin, Campus Benjamin Franklin	Berlin
Germany	Elisabeth Hospital	Essen

Sponsors (3)

Lead Sponsor	Collaborator
Charite University, Berlin, Germany	Cardiology and Angiology, Elisabeth Hospital, Essen, Germany, Center for Stroke Research Berlin

Country where clinical trial is conducted

Germany, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Sensitivity and specificity of contrast medium-enhanced cardiac magnetic resonance imaging to detect echocardiography-proven cardiac sources of embolism in patients with acute ischemic stroke.		< 1 week after ischemic stroke	No
Secondary	Rate of unrecognised myocardial infarction detected by late gadolinium-enhanced cardiac MRI in patients with acute ischemic stroke.		< 1 week after ischemic stroke	No