Stroke Clinical Trial
Official title:
PRoFESS - Prevention Regimen For Effectively Avoiding Second Strokes: A Double-blind, Active and Placebo Controlled Study of Aggrenox vs. Clopidogrel, With and Without Micardis
| NCT number | NCT00153062 |
| Other study ID # | 9.159 |
| Secondary ID | |
| Status | Completed |
| Phase | Phase 4 |
| First received | September 9, 2005 |
| Last updated | April 22, 2014 |
| Start date | August 2003 |
The purpose of the trial is to determine if extended-release dipyridamole + aspirin [Aggrenox, Asasa ntin] is superior to clopidogrel [Plavix], and if telmisartan [Micardis, Gliosartan, Kinzal, Kinzalm ono, Predxal, Pritor, Samertan, Telmisartan] is superior to placebo, in the presence of background antihypertensive therapy, in prevention of a second stroke in patients who have recently suffered a stroke and therefore are at high risk of suffering another one.
| Status | Completed |
| Enrollment | 20332 |
| Est. completion date | |
| Est. primary completion date | April 2008 |
| Accepts healthy volunteers | No |
| Gender | Both |
| Age group | 50 Years and older |
| Eligibility |
Inclusion criteria: Male or female subjects 55 year or older who have suffered an ischemic stroke within the past 90 days and who meet all other inclusion criteria. Include also patients of ages 50 - 54 years and/or 90 to 120 days after the qualifying stroke provided the patient has at least two of the following additional risk factors: - Diabetes mellitus - Hypertension (systolic BP ¿ 140 or diastolic BP ¿ 90) - Smoker at time of qualifying stroke - Obesity (BMI>30; BMI=weight (kg)/[height (m)]2) - Previous vascular disease (stroke, MI, or peripheral arterial disease prior to qualifying stroke) - End-organ-damage (retinopathy, LVH, or microalbuminuria) - Hyperlipidemia Exclusion criteria: hemorrhagic stroke (must be ruled out by imaging);unable to give informed consent; known brain tumor, severe renal or hepatic insufficiency, current active peptic ulcer disease, severe coronary artery disease including unstable angina pectoris or an MI within the previous 3 months,or history of a hemostatic disorder or systemic bleeding ;hyperkalemia;uncorrected volume or sodium depletion; pre-stroke history of dementia;modified Rankin score greater than 4;qualifying stroke induced by surgical or cardiovascular procedure;uncontrolled hypertension at entry above 180/110 mmHg (goal BPs are lower); SBP 120 mmHg or less for hospitalized patients; currently taking an ARB and not able or willing to switch to alternative; required or planned continuing treatment with antithrombotics or anticoagulants including heparin or warfarin or non-study platelet inhibitors; syndrome of asthma, rhinitis and nasal polyps;scheduled for major surgery, carotid endarterectomy, or carotid angioplasty (4 weeks post surgery is allowed);unlikely to be released from hospital following the qualifying stroke or presence of a severe disability likely to lead to being bedridden or demented or a non-vascular disease or condition which makes it unlikely that the patient will survive to the end of the trial; history of thrombocytopenia or neutropenia. |
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double-Blind, Primary Purpose: Prevention
| Country | Name | City | State |
|---|---|---|---|
| Argentina | 9.159.1331 Boehringer Ingelheim Investigational Site | Capital Federal | |
| Argentina | 9.159.1333 Boehringer Ingelheim Investigational Site | Capital Federal | |
| Argentina | 9.159.1334 Boehringer Ingelheim Investigational Site | Capital Federal | |
| Argentina | 9.159.1335 Boehringer Ingelheim Investigational Site | Capital Federal | |
| Argentina | 9.159.1336 Boehringer Ingelheim Investigational Site | Capital Federal | |
| Argentina | 9.159.1332 Boehringer Ingelheim Investigational Site | Rosario, Sta. Fe | |
| Argentina | 9.159.1342 Boehringer Ingelheim Investigational Site | Santa Fe | |
| Australia | 9.159.2451 Boehringer Ingelheim Investigational Site | Bedford Park | South Australia |
| Australia | 9.159.2443 Boehringer Ingelheim Investigational Site | Box Hill | Victoria |
| Australia | 9.159.2444 Boehringer Ingelheim Investigational Site | Gosford | New South Wales |
| Australia | 9.159.2450 Boehringer Ingelheim Investigational Site | Herston | Queensland |
| Australia | 9.159.2447 Boehringer Ingelheim Investigational Site | Melbourne | Victoria |
| Australia | 9.159.2449 Boehringer Ingelheim Investigational Site | New Lambton | New South Wales |
| Australia | 9.159.2445 Boehringer Ingelheim Investigational Site | Parkville | Victoria |
| Australia | 9.159.2452 Boehringer Ingelheim Investigational Site | Southport | Queensland |
| Australia | 9.159.2446 Boehringer Ingelheim Investigational Site | West Heidelberg | Victoria |
| Australia | 9.159.2448 Boehringer Ingelheim Investigational Site | Westmead | New South Wales |
| Austria | 9.159.1515 Boehringer Ingelheim Investigational Site | Graz | |
| Austria | 9.159.1519 Boehringer Ingelheim Investigational Site | Graz | |
| Austria | 9.159.1517 Boehringer Ingelheim Investigational Site | Innsbruck | |
| Austria | 9.159.1516 Boehringer Ingelheim Investigational Site | Linz | |
| Austria | 9.159.1518 Boehringer Ingelheim Investigational Site | Ma.Gugging/Klosterneuburg | |
| Austria | 9.159.1520 Boehringer Ingelheim Investigational Site | St. Pölten | |
| Austria | 9.159.1521 Boehringer Ingelheim Investigational Site | Wien | |
| Belgium | 9.159.1553 Boehringer Ingelheim Investigational Site | Aalst | |
| Belgium | 9.159.1543 Boehringer Ingelheim Investigational Site | Anderlecht | |
| Belgium | 9.159.1552 Boehringer Ingelheim Investigational Site | Antwerpen | |
| Belgium | 9.159.1546 Boehringer Ingelheim Investigational Site | Bonheiden | |
| Belgium | 9.159.1547 Boehringer Ingelheim Investigational Site | Brugge | |
| Belgium | 9.159.1550 Boehringer Ingelheim Investigational Site | Bruxelles | |
| Belgium | 9.159.1549 Boehringer Ingelheim Investigational Site | Hasselt | |
| Belgium | 9.159.1555 Boehringer Ingelheim Investigational Site | Kortrijk | |
| Belgium | 9.159.1554 Boehringer Ingelheim Investigational Site | La Louvière | |
| Belgium | 9.159.1544 Boehringer Ingelheim Investigational Site | Leuven | |
| Belgium | 9.159.1548 Boehringer Ingelheim Investigational Site | Montegnée | |
| Belgium | 9.159.1556 Boehringer Ingelheim Investigational Site | Ottignies | |
| Belgium | 9.159.1545 Boehringer Ingelheim Investigational Site | Wilrijk | |
| Belgium | 9.159.1551 Boehringer Ingelheim Investigational Site | Yvoir | |
| Brazil | 9.159.2869 Complexo Hospitalar Universitario Prof Edgard Santos | Salvador | |
| Brazil | 9.159.2853 Boehringer Ingelheim Investigational Site | São Paulo | |
| Canada | 9.159.1393 Boehringer Ingelheim Investigational Site | Barrie | Ontario |
| Canada | 9.159.1397 Foothills Medical Centre | Calgary | Alberta |
| Canada | 9.159.1392 Boehringer Ingelheim Investigational Site | Corner Brook | Newfoundland and Labrador |
| Canada | 9.159.1382 Boehringer Ingelheim Investigational Site | Edmonton | Alberta |
| Canada | 9.159.1359 Boehringer Ingelheim Investigational Site | Greenfield Park | Quebec |
| Canada | 9.159.1395 Boehringer Ingelheim Investigational Site | Hamilton | Ontario |
| Canada | 9.159.1370 Boehringer Ingelheim Investigational Site | Kamloops | British Columbia |
| Canada | 9.159.1360 Boehringer Ingelheim Investigational Site | Kingston | Ontario |
| Canada | 9.159.1390 Boehringer Ingelheim Investigational Site | Lethbridge | Alberta |
| Canada | 9.159.1367 Boehringer Ingelheim Investigational Site | London | Ontario |
| Canada | 9.159.1384 Boehringer Ingelheim Investigational Site | London | Ontario |
| Canada | 9.159.1380 Boehringer Ingelheim Investigational Site | Mississauga | Ontario |
| Canada | 9.159.1361 Boehringer Ingelheim Investigational Site | Montreal | Quebec |
| Canada | 9.159.1362 Boehringer Ingelheim Investigational Site | Montreal | Quebec |
| Canada | 9.159.1371 Boehringer Ingelheim Investigational Site | Montreal | Quebec |
| Canada | 9.159.1374 Boehringer Ingelheim Investigational Site | Montreal | Quebec |
| Canada | 9.159.1388 Boehringer Ingelheim Investigational Site | Montreal | Quebec |
| Canada | 9.159.1368 Boehringer Ingelheim Investigational Site | New Westminster | British Columbia |
| Canada | 9.159.1378 Boehringer Ingelheim Investigational Site | Ottawa | Ontario |
| Canada | 9.159.1381 Ottawa Hospital General Campus | Ottawa | Ontario |
| Canada | 9.159.1376 Boehringer Ingelheim Investigational Site | Penticton | British Columbia |
| Canada | 9.159.1372 Boehringer Ingelheim Investigational Site | Quebec City | Quebec |
| Canada | 9.159.1389 Boehringer Ingelheim Investigational Site | Regina | Saskatchewan |
| Canada | 9.159.1366 Boehringer Ingelheim Investigational Site | Richmond Hill | Ontario |
| Canada | 9.159.1358 Boehringer Ingelheim Investigational Site | Saguenay | Quebec |
| Canada | 9.159.1356 Boehringer Ingelheim Investigational Site | Saint John | New Brunswick |
| Canada | 9.159.1396 Boehringer Ingelheim Investigational Site | Saskatoon | Saskatchewan |
| Canada | 9.159.1365 Boehringer Ingelheim Investigational Site | Scarborough | Ontario |
| Canada | 9.159.1375 Boehringer Ingelheim Investigational Site | Scarborough | Ontario |
| Canada | 9.159.1364 Boehringer Ingelheim Investigational Site | St. Jerome | Quebec |
| Canada | 9.159.1385 Boehringer Ingelheim Investigational Site | St. John's | Newfoundland and Labrador |
| Canada | 9.159.1373 Boehringer Ingelheim Investigational Site | Sydney | Nova Scotia |
| Canada | 9.159.1391 Boehringer Ingelheim Investigational Site | Tecumseh | Ontario |
| Canada | 9.159.1369 Boehringer Ingelheim Investigational Site | Thunder Bay | Ontario |
| Canada | 9.159.1357 Boehringer Ingelheim Investigational Site | Toronto | Ontario |
| Canada | 9.159.1379 Boehringer Ingelheim Investigational Site | Toronto | Ontario |
| Canada | 9.159.1383 Boehringer Ingelheim Investigational Site | Toronto | Ontario |
| Canada | 9.159.1387 Boehringer Ingelheim Investigational Site | Vancouver | British Columbia |
| Canada | 9.159.1377 Boehringer Ingelheim Investigational Site | Victoria | British Columbia |
| Canada | 9.159.1363 Boehringer Ingelheim Investigational Site | Windsor | Ontario |
| Canada | 9.159.1355 Boehringer Ingelheim Investigational Site | Winnipeg | Manitoba |
| Canada | 9.159.1394 Boehringer Ingelheim Investigational Site | Winnipeg | Manitoba |
| China | 9.159.2490 Boehringer Ingelheim Investigational Site | Beijing | |
| China | 9.159.2491 Boehringer Ingelheim Investigational Site | Beijing | |
| China | 9.159.2492 Boehringer Ingelheim Investigational Site | Beijing | |
| China | 9.159.2493 Boehringer Ingelheim Investigational Site | Beijing | |
| China | 9.159.2494 Boehringer Ingelheim Investigational Site | Beijing | |
| China | 9.159.2495 Boehringer Ingelheim Investigational Site | Beijing | |
| China | 9.159.2496 Boehringer Ingelheim Investigational Site | Beijing | |
| China | 9.159.2503 Boehringer Ingelheim Investigational Site | Changchun, Jilin Province | |
| China | 9.159.2500 Boehringer Ingelheim Investigational Site | Changsha, Hunan Province | |
| China | 9.159.2513 Boehringer Ingelheim Investigational Site | Chengdu, Sichuan Province | |
| China | 9.159.2512 Boehringer Ingelheim Investigational Site | Chongqing | |
| China | 9.159.2509 Boehringer Ingelheim Investigational Site | Guangzhou | |
| China | 9.159.2518 Boehringer Ingelheim Investigational Site | Guangzhou | |
| China | 9.159.2521 Boehringer Ingelheim Investigational Site | Guangzhou | |
| China | 9.159.2507 Boehringer Ingelheim Investigational Site | Guangzhou, Guangdong Province | |
| China | 9.159.2510 Boehringer Ingelheim Investigational Site | Guangzhou, Guangdong Province | |
| China | 9.159.2502 Boehringer Ingelheim Investigational Site | Hangzhou, Zhejiang Province | |
| China | 9.159.2504 Boehringer Ingelheim Investigational Site | Harbin, Heilongjiang Province | |
| China | 9.159.2505 Boehringer Ingelheim Investigational Site | Jinan, Shandong Province | |
| China | 9.159.2506 Boehringer Ingelheim Investigational Site | Jinan, Shangdong Province | |
| China | 9.159.2517 Boehringer Ingelheim Investigational Site | Nanjing, Jiangsu Province | |
| China | 9.159.2519 Boehringer Ingelheim Investigational Site | Nanjing, Jiangsu Province | |
| China | 9.159.2520 Boehringer Ingelheim Investigational Site | Nanjing, Jiangsu Province | |
| China | 9.159.2483 Boehringer Ingelheim Investigational Site | Shanghai | |
| China | 9.159.2484 Boehringer Ingelheim Investigational Site | Shanghai | |
| China | 9.159.2485 Boehringer Ingelheim Investigational Site | Shanghai | |
| China | 9.159.2486 Boehringer Ingelheim Investigational Site | Shanghai | |
| China | 9.159.2487 Boehringer Ingelheim Investigational Site | Shanghai | |
| China | 9.159.2488 Boehringer Ingelheim Investigational Site | Shanghai | |
| China | 9.159.2489 Boehringer Ingelheim Investigational Site | Shanghai | |
| China | 9.159.2516 Boehringer Ingelheim Investigational Site | Suzhou, Jiangsu Province | |
| China | 9.159.2497 Boehringer Ingelheim Investigational Site | Tianjin | |
| China | 9.159.2501 Boehringer Ingelheim Investigational Site | Wenzhou, Zhejiang Province | |
| China | 9.159.2498 Boehringer Ingelheim Investigational Site | Wuhan, Hubei Province | |
| China | 9.159.2499 Boehringer Ingelheim Investigational Site | Wuhan, Hubei Province | |
| China | 9.159.2511 Boehringer Ingelheim Investigational Site | Xian | |
| China | 9.159.2514 Boehringer Ingelheim Investigational Site | Xian, Shanxi | |
| China | 9.159.2515 Boehringer Ingelheim Investigational Site | Xian, Shanxi Province | |
| Denmark | 9.159.1636 Boehringer Ingelheim Investigational Site | Aarhuc C | |
| Denmark | 9.159.1635 Boehringer Ingelheim Investigational Site | Aarhus C | |
| Denmark | 9.159.1639 Boehringer Ingelheim Investigational Site | Esbjerg | |
| Denmark | 9.159.1634 Boehringer Ingelheim Investigational Site | Frederiksberg | |
| Denmark | 9.159.1637 Boehringer Ingelheim Investigational Site | Glostrup | |
| Denmark | 9.159.1640 Boehringer Ingelheim Investigational Site | Hellerup | |
| Denmark | 9.159.1638 Boehringer Ingelheim Investigational Site | Hvidovre | |
| Denmark | 9.159.1633 Boehringer Ingelheim Investigational Site | København NV | |
| Denmark | 9.159.1631 Boehringer Ingelheim Investigational Site | København Ø | |
| Denmark | 9.159.1632 Boehringer Ingelheim Investigational Site | Odense | |
| El Salvador | 9.159.2181 Boehringer Ingelheim Investigational Site | Oviedo | |
| Finland | 9.159.1655 Boehringer Ingelheim Investigational Site | Helsinki | |
| Finland | 9.159.1658 Boehringer Ingelheim Investigational Site | Kuopio | |
| Finland | 9.159.1659 Boehringer Ingelheim Investigational Site | Lappeenranta | |
| Finland | 9.159.1656 Boehringer Ingelheim Investigational Site | Oulu | |
| Finland | 9.159.1657 Boehringer Ingelheim Investigational Site | Seinäjoki | |
| France | 9.159.1680 Boehringer Ingelheim Investigational Site | Lille cedex | |
| France | 9.159.1683 Boehringer Ingelheim Investigational Site | Limoges cedex 1 | |
| France | 9.159.1681 Boehringer Ingelheim Investigational Site | Marseille cedex 05 | |
| France | 9.159.1679 Boehringer Ingelheim Investigational Site | Nancy | |
| France | 9.159.1685 Boehringer Ingelheim Investigational Site | Paris cedex 19 | |
| France | 9.159.1682 Boehringer Ingelheim Investigational Site | Poitiers cedex | |
| France | 9.159.1684 Boehringer Ingelheim Investigational Site | Tours cedex 9 | |
| Germany | 9.159.1713 Boehringer Ingelheim Investigational Site | Bad Neustadt/Saale | |
| Germany | 9.159.1736 Boehringer Ingelheim Investigational Site | Berlin | |
| Germany | 9.159.1732 Boehringer Ingelheim Investigational Site | Braunschweig | |
| Germany | 9.159.1726 Boehringer Ingelheim Investigational Site | Cloppenburg | |
| Germany | 9.159.1723 Boehringer Ingelheim Investigational Site | Dresden | |
| Germany | 9.159.1728 Boehringer Ingelheim Investigational Site | Düsseldorf | |
| Germany | 9.159.1707 Boehringer Ingelheim Investigational Site | Essen | |
| Germany | 9.159.1738 Boehringer Ingelheim Investigational Site | Freiburg | |
| Germany | 9.159.1720 Boehringer Ingelheim Investigational Site | Gießen | |
| Germany | 9.159.1722 Boehringer Ingelheim Investigational Site | Hamburg | |
| Germany | 9.159.1739 Boehringer Ingelheim Investigational Site | Hamburg | |
| Germany | 9.159.1724 Boehringer Ingelheim Investigational Site | Heidelberg | |
| Germany | 9.159.1734 Boehringer Ingelheim Investigational Site | Jena | |
| Germany | 9.159.1730 Boehringer Ingelheim Investigational Site | Kaiserslautern | |
| Germany | 9.159.1737 Boehringer Ingelheim Investigational Site | Köln | |
| Germany | 9.159.1717 Boehringer Ingelheim Investigational Site | Leipzig | |
| Germany | 9.159.1735 Boehringer Ingelheim Investigational Site | Ludwigshafen am Rhein | |
| Germany | 9.159.1712 Boehringer Ingelheim Investigational Site | Magdeburg | |
| Germany | 9.159.1710 Boehringer Ingelheim Investigational Site | Mainz | |
| Germany | 9.159.1709 Boehringer Ingelheim Investigational Site | Minden | |
| Germany | 9.159.1716 Boehringer Ingelheim Investigational Site | Mönchengladbach | |
| Germany | 9.159.1718 Boehringer Ingelheim Investigational Site | München | |
| Germany | 9.159.1725 Boehringer Ingelheim Investigational Site | München | |
| Germany | 9.159.1729 Boehringer Ingelheim Investigational Site | München | |
| Germany | 9.159.1727 Boehringer Ingelheim Investigational Site | Münster | |
| Germany | 9.159.1711 Boehringer Ingelheim Investigational Site | Nürnberg | |
| Germany | 9.159.1719 Boehringer Ingelheim Investigational Site | Regensburg | |
| Germany | 9.159.1731 Boehringer Ingelheim Investigational Site | Remscheid | |
| Germany | 9.159.1708 Boehringer Ingelheim Investigational Site | Rostock | |
| Germany | 9.159.1715 Boehringer Ingelheim Investigational Site | Saarbrücken | |
| Germany | 9.159.1714 Boehringer Ingelheim Investigational Site | Siegen | |
| Germany | 9.159.1733 Boehringer Ingelheim Investigational Site | Stuttgart | |
| Germany | 9.159.1721 Boehringer Ingelheim Investigational Site | Weimar | |
| Greece | 9.159.1826 Boehringer Ingelheim Investigational Site | Alexandroupolis | |
| Greece | 9.159.1819 Boehringer Ingelheim Investigational Site | Athens | |
| Greece | 9.159.1820 Boehringer Ingelheim Investigational Site | Athens | |
| Greece | 9.159.1821 Boehringer Ingelheim Investigational Site | Athens | |
| Greece | 9.159.1825 Boehringer Ingelheim Investigational Site | Ioannina | |
| Greece | 9.159.1824 Boehringer Ingelheim Investigational Site | Patras | |
| Hong Kong | 9.159.2713 Boehringer Ingelheim Investigational Site | Hong KoNG | |
| Hong Kong | 9.159.2714 Boehringer Ingelheim Investigational Site | Hong Kong | |
| India | 9.159.2605 Boehringer Ingelheim Investigational Site | Annamalainagar | |
| India | 9.159.2603 Boehringer Ingelheim Investigational Site | Bangalore | |
| India | 9.159.2620 Boehringer Ingelheim Investigational Site | Bangalore | |
| India | 9.159.2616 Boehringer Ingelheim Investigational Site | Bikaner | |
| India | 9.159.2618 Boehringer Ingelheim Investigational Site | Calicut | |
| India | 9.159.2604 Boehringer Ingelheim Investigational Site | Chennai | |
| India | 9.159.2619 Boehringer Ingelheim Investigational Site | Chennai | |
| India | 9.159.2625 Boehringer Ingelheim Investigational Site | Chennai | |
| India | 9.159.2606 Boehringer Ingelheim Investigational Site | Cochin | |
| India | 9.159.2607 Boehringer Ingelheim Investigational Site | Hyderabad | |
| India | 9.159.2624 Boehringer Ingelheim Investigational Site | Hyderabad | |
| India | 9.159.2630 Boehringer Ingelheim Investigational Site | Hyderabad | |
| India | 9.159.2632 Boehringer Ingelheim Investigational Site | Hyderabad | |
| India | 9.159.2610 Boehringer Ingelheim Investigational Site | Indore | |
| India | 9.159.2615 Boehringer Ingelheim Investigational Site | Jaipur | |
| India | 9.159.2617 Boehringer Ingelheim Investigational Site | Jaipur | |
| India | 9.159.2612 Boehringer Ingelheim Investigational Site | Jodhpur | |
| India | 9.159.2621 Boehringer Ingelheim Investigational Site | Kottayam | |
| India | 9.159.2613 Boehringer Ingelheim Investigational Site | Lucknow | |
| India | 9.159.2614 Boehringer Ingelheim Investigational Site | Ludhiana | |
| India | 9.159.2611 Boehringer Ingelheim Investigational Site | Mumbai | |
| India | 9.159.2628 Boehringer Ingelheim Investigational Site | New Delhi | |
| India | 9.159.2629 Boehringer Ingelheim Investigational Site | New Delhi | |
| India | 9.159.2623 Boehringer Ingelheim Investigational Site | Patiala | |
| India | 9.159.2609 Boehringer Ingelheim Investigational Site | Pune | |
| India | 9.159.2622 Boehringer Ingelheim Investigational Site | Pune | |
| India | 9.159.2627 Boehringer Ingelheim Investigational Site | Secunderabad | |
| India | 9.159.2626 Boehringer Ingelheim Investigational Site | Trichy | |
| India | 9.159.2631 Boehringer Ingelheim Investigational Site | Visakhapatnam | |
| India | 9.159.2608 Boehringer Ingelheim Investigational Site | Wardha | |
| Ireland | 9.159.1851 Boehringer Ingelheim Investigational Site | Cork | |
| Ireland | 9.159.1852 Boehringer Ingelheim Investigational Site | Dublin 7 | |
| Israel | 9.159.2729 Barzilai Medical Center | Ashkelon | |
| Israel | 9.159.2721 Neurology Unit | Haifa | |
| Israel | 9.159.2724 Rambam Medical Center, Tel-Aviv Medical | Haifa | |
| Israel | 9.159.2723 Boehringer Ingelheim Investigational Site | Israel | |
| Israel | 9.159.2727 Western Galilee Hospital | Naharia | |
| Israel | 9.159.2722 Neurology Unit | Petach Tikva | |
| Israel | 9.159.2726 Sheba Medical Center | Tel Hashomer | |
| Israel | 9.159.2725 Tel Aviv Medical Center | Tel-Aviv | |
| Italy | 9.159.1875 Università degli Studi di Ancona | Ancona | |
| Italy | 9.159.1882 Ospedale Brotzu | Cagliari | |
| Italy | 9.159.1883 Azienda Ospedaliera S. Anna | Como | |
| Italy | 9.159.1871 Azienda Ospedaliera "Careggi" | Firenze | |
| Italy | 9.159.1869 Università degli Studi di Genova | Genova | |
| Italy | 9.159.1870 ASL No. 5 di Jesi | Jesi (ancona) | |
| Italy | 9.159.1865 Ospedale Regionale "S. Salvatore" | L'aquila | |
| Italy | 9.159.1866 Ospedale S. Raffaele | Milano | |
| Italy | 9.159.1873 Istituto Scientifico "S. Luca" | Milano | |
| Italy | 9.159.1884 Ospedale S. Carlo Borromeo" | Milano | |
| Italy | 9.159.1868 Ospedale "S. Maria di Loreto Mare" | Napoli | |
| Italy | 9.159.1876 Azienda Ospedaliera di Padova -Policlinico Universitario | Padova | |
| Italy | 9.159.1874 Ospedale Civico - ARNAS | Palermo | |
| Italy | 9.159.1872 Neuromed IRCCS | Pozzilli (IS) | |
| Italy | 9.159.1879 Policlinico S. Andrea | Roma | |
| Italy | 9.159.1881 Università "La Sapienza" | Roma | |
| Italy | 9.159.1877 Azienda Ospedaliera Umberto I | Siracusa | |
| Italy | 9.159.1878 Azienda Ospedaliera "Santo Maria" | Terni | |
| Italy | 9.159.1864 Azienda Ospedaliera "S. Giovanni Battista" | Torino | |
| Italy | 9.159.1863 Ospedale di Cattinara | Trieste | |
| Italy | 9.159.1867 Presidio Ospedaliero G.Jazzolino | Vibo Valentia | |
| Italy | 9.159.1880 Ospedale Civile | Vicenza | |
| Japan | 9.159.2964 Boehringer Ingelheim Investigational Site | Adachi-ku, Tokyo | |
| Japan | 9.159.2958 Boehringer Ingelheim Investigational Site | Akashi, Hyogo | |
| Japan | 9.159.2970 Boehringer Ingelheim Investigational Site | Akashi, Hyogo | |
| Japan | 9.159.2965 Boehringer Ingelheim Investigational Site | Ako, Hyogo | |
| Japan | 9.159.2968 Boehringer Ingelheim Investigational Site | Aoba-ku, Yokohama, Kanagawa | |
| Japan | 9.159.2951 Boehringer Ingelheim Investigational Site | Azumino, Nagano | |
| Japan | 9.159.2959 Boehringer Ingelheim Investigational Site | Chitose, Hokkaido | |
| Japan | 9.159.2944 Boehringer Ingelheim Investigational Site | Chuo-ku, Kobe, Hyogo | |
| Japan | 9.159.2947 Boehringer Ingelheim Investigational Site | Chuo-Ku, Sapporo, Hokkaido | |
| Japan | 9.159.2954 Boehringer Ingelheim Investigational Site | Fushimi-ku, Kyoto, Kyoto | |
| Japan | 9.159.2942 Boehringer Ingelheim Investigational Site | Habikino, Osaka | |
| Japan | 9.159.2948 Boehringer Ingelheim Investigational Site | Higashi-ku, Sapporo, Hokkaido | |
| Japan | 9.159.2957 Boehringer Ingelheim Investigational Site | Higashi-osaka, Osaka | |
| Japan | 9.159.2940 Boehringer Ingelheim Investigational Site | Higashinari-ku, Osaka, Osaka | |
| Japan | 9.159.2973 Boehringer Ingelheim Investigational Site | Higashiyodogawa-ku, Osaka, Osaka | |
| Japan | 9.159.2949 Boehringer Ingelheim Investigational Site | Hitachinaka, Ibaraki | |
| Japan | 9.159.2953 Boehringer Ingelheim Investigational Site | Iida, Nagano | |
| Japan | 9.159.2943 Boehringer Ingelheim Investigational Site | Izumisano, Osaka | |
| Japan | 9.159.2963 Boehringer Ingelheim Investigational Site | Jyonan-ku, Fukuoka, Fukuoka | |
| Japan | 9.159.2933 Boehringer Ingelheim Investigational Site | Kasama, Ibaraki | |
| Japan | 9.159.2955 Boehringer Ingelheim Investigational Site | Kasuga, Fukuoka | |
| Japan | 9.159.2938 Boehringer Ingelheim Investigational Site | Kita-ku, Osaka, Osaka | |
| Japan | 9.159.2967 Boehringer Ingelheim Investigational Site | Koriyama, Fukushima | |
| Japan | 9.159.2969 Boehringer Ingelheim Investigational Site | Kushiro, Hokkaido | |
| Japan | 9.159.2952 Boehringer Ingelheim Investigational Site | Matsumoto, Nagano | |
| Japan | 9.159.2961 Boehringer Ingelheim Investigational Site | Midori-ku, Yokohama, Kanagawa | |
| Japan | 9.159.2934 Boehringer Ingelheim Investigational Site | Moriya, Ibaraki | |
| Japan | 9.159.2971 Boehringer Ingelheim Investigational Site | Musashino, Tokyo | |
| Japan | 9.159.2962 Boehringer Ingelheim Investigational Site | Nakagawa-ku, Nagoya, Aichi | |
| Japan | 9.159.2939 Boehringer Ingelheim Investigational Site | Nishi-yodogawa-ku, Osaka, Osaka | |
| Japan | 9.159.2956 Boehringer Ingelheim Investigational Site | Ohnojo, Fukuoka | |
| Japan | 9.159.2941 Boehringer Ingelheim Investigational Site | Sakai-ku, Sakai, Osaka | |
| Japan | 9.159.2945 Boehringer Ingelheim Investigational Site | Sawara-ku, Fukuoka, Fukuoka | |
| Japan | 9.159.2937 Boehringer Ingelheim Investigational Site | Shimogyo-ku, Kyoto, Kyoto | |
| Japan | 9.159.2966 Boehringer Ingelheim Investigational Site | Shiroishi, Miyagi | |
| Japan | 9.159.2936 Boehringer Ingelheim Investigational Site | Suwa, Nagano | |
| Japan | 9.159.2946 Boehringer Ingelheim Investigational Site | Takikawa, Hokkaido | |
| Japan | 9.159.2935 Boehringer Ingelheim Investigational Site | Tatebayashi, Gunma | |
| Japan | 9.159.2950 Boehringer Ingelheim Investigational Site | Tsuchiura, Ibaraki | |
| Japan | 9.159.2972 Boehringer Ingelheim Investigational Site | Yao, Osaka | |
| Korea, Republic of | 9.159.1593 Boehringer Ingelheim Investigational Site | Gwangju | |
| Korea, Republic of | 9.159.1595 Boehringer Ingelheim Investigational Site | Incheon | |
| Korea, Republic of | 9.159.1592 Boehringer Ingelheim Investigational Site | Kyunggi-do | |
| Korea, Republic of | 9.159.1591 Boehringer Ingelheim Investigational Site | Seoul | |
| Korea, Republic of | 9.159.1594 Boehringer Ingelheim Investigational Site | Seoul | |
| Korea, Republic of | 9.159.1597 Boehringer Ingelheim Investigational Site | Seoul | |
| Korea, Republic of | 9.159.1596 Boehringer Ingelheim Investigational Site | Suwon | |
| Malaysia | 9.159.2707 Boehringer Ingelheim Investigational Site | Kelantan Darul Naim | |
| Malaysia | 9.159.2706 Boehringer Ingelheim Investigational Site | Kuala Lumpur | |
| Mexico | 9.159.2765 Boehringer Ingelheim Investigational Site | Metepec | |
| Netherlands | 9.159.1960 Jeroen Bosch Ziekenhuis | 's-Hertogenbosch | |
| Netherlands | 9.159.1945 Medisch Centrum Alkmaar | Alkmaar | |
| Netherlands | 9.159.1963 Polikliniek Neurologie | Assen | |
| Netherlands | 9.159.1949 Ziekenhuis Gooi-Noord | Blaricum | |
| Netherlands | 9.159.1962 Locatie Molengracht | Breda | |
| Netherlands | 9.159.1950 HagaZiekenhuis | Den Haag | |
| Netherlands | 9.159.1959 Catharina Ziekenhuis | Eindhoven | |
| Netherlands | 9.159.1946 Scheper Ziekenhuis | Emmen | |
| Netherlands | 9.159.1958 Medisch Spectrum Twente | Enschede | |
| Netherlands | 9.159.1943 Umcg | Groningen | |
| Netherlands | 9.159.1961 Lokatie Van Swieten | Groningen | |
| Netherlands | 9.159.1953 Atrium Medisch Centrum | Heerlen | |
| Netherlands | 9.159.1955 Elkerliek Ziekenhuis | Helmond | |
| Netherlands | 9.159.1951 Ziekenhuisgroep Twente | Hengelo | |
| Netherlands | 9.159.1948 Medisch Centrum Leeuwarden | Leeuwarden | |
| Netherlands | 9.159.1952 Rijnland Ziekenhuis | Leiderdorp | |
| Netherlands | 9.159.1947 Sint Antonius Ziekenhuis | Nieuwegein | |
| Netherlands | 9.159.1964 Canisius-Wilhelmina ziekenhuis | Nijmegen | |
| Netherlands | 9.159.1956 TweeSteden Ziekenhuis Tilburg | Tilburg | |
| Netherlands | 9.159.1957 Sint Elisabeth Ziekenhuis | Tilburg | |
| Netherlands | 9.159.1944 Máxima Medisch Centrum | Veldhoven | |
| Netherlands | 9.159.1954 St. Jans Gasthuis | Weert | |
| Norway | 9.159.2029 Boehringer Ingelheim Investigational Site | Bergen | |
| Norway | 9.159.2028 Boehringer Ingelheim Investigational Site | Oslo | |
| Norway | 9.159.2027 Boehringer Ingelheim Investigational Site | Trondheim | |
| Portugal | 9.159.2040 Hospital Fernando Fonseca | Amadora | |
| Portugal | 9.159.2039 Centro Hospitalar e Universitário de Coimbra, EPE | Coimbra | |
| Portugal | 9.159.2041 Centro Hospitalar de Lisboa Norte | Lisboa | |
| Portugal | 9.159.2042 Centro Hospitalar do Porto | Porto | |
| Russian Federation | 9.159.2114 Boehringer Ingelheim Investigational Site | Ekaterinburg | |
| Russian Federation | 9.159.2102 Boehringer Ingelheim Investigational Site | Kazan | |
| Russian Federation | 9.159.2117 Boehringer Ingelheim Investigational Site | Kemerovo | |
| Russian Federation | 9.159.2107 Boehringer Ingelheim Investigational Site | Kirov | |
| Russian Federation | 9.159.2116 Boehringer Ingelheim Investigational Site | Krasnoyarsk | |
| Russian Federation | 9.159.2079 Boehringer Ingelheim Investigational Site | Moscow | |
| Russian Federation | 9.159.2080 Boehringer Ingelheim Investigational Site | Moscow | |
| Russian Federation | 9.159.2081 Boehringer Ingelheim Investigational Site | Moscow | |
| Russian Federation | 9.159.2082 Boehringer Ingelheim Investigational Site | Moscow | |
| Russian Federation | 9.159.2083 Boehringer Ingelheim Investigational Site | Moscow | |
| Russian Federation | 9.159.2084 Boehringer Ingelheim Investigational Site | Moscow | |
| Russian Federation | 9.159.2085 Boehringer Ingelheim Investigational Site | Moscow | |
| Russian Federation | 9.159.2087 Boehringer Ingelheim Investigational Site | Moscow | |
| Russian Federation | 9.159.2088 Boehringer Ingelheim Investigational Site | Moscow | |
| Russian Federation | 9.159.2089 Boehringer Ingelheim Investigational Site | Moscow | |
| Russian Federation | 9.159.2090 Boehringer Ingelheim Investigational Site | Moscow | |
| Russian Federation | 9.159.2091 Boehringer Ingelheim Investigational Site | Moscow | |
| Russian Federation | 9.159.2092 Boehringer Ingelheim Investigational Site | Moscow | |
| Russian Federation | 9.159.2093 Boehringer Ingelheim Investigational Site | Moscow | |
| Russian Federation | 9.159.2095 Boehringer Ingelheim Investigational Site | Moscow | |
| Russian Federation | 9.159.2098 Boehringer Ingelheim Investigational Site | Moscow | |
| Russian Federation | 9.159.2101 Boehringer Ingelheim Investigational Site | Moscow | |
| Russian Federation | 9.159.2105 Boehringer Ingelheim Investigational Site | Nizhnyi Novgorod | |
| Russian Federation | 9.159.2115 Boehringer Ingelheim Investigational Site | Novosibirsk | |
| Russian Federation | 9.159.2119 Boehringer Ingelheim Investigational Site | Omsk | |
| Russian Federation | 9.159.2111 Boehringer Ingelheim Investigational Site | Orel | |
| Russian Federation | 9.159.2106 Boehringer Ingelheim Investigational Site | Rostov-na-Donu | |
| Russian Federation | 9.159.2108 Boehringer Ingelheim Investigational Site | Samara | |
| Russian Federation | 9.159.2109 Boehringer Ingelheim Investigational Site | Saratov | |
| Russian Federation | 9.159.2110 Boehringer Ingelheim Investigational Site | Saratov | |
| Russian Federation | 9.159.2118 Boehringer Ingelheim Investigational Site | Seversk | |
| Russian Federation | 9.159.2086 Boehringer Ingelheim Investigational Site | Smolensk | |
| Russian Federation | 9.159.2094 Boehringer Ingelheim Investigational Site | St. Petersburg | |
| Russian Federation | 9.159.2097 Boehringer Ingelheim Investigational Site | St. Petersburg | |
| Russian Federation | 9.159.2099 Boehringer Ingelheim Investigational Site | St. Petersburg | |
| Russian Federation | 9.159.2100 Boehringer Ingelheim Investigational Site | St. Petersburg | |
| Russian Federation | 9.159.2120 Boehringer Ingelheim Investigational Site | Ufa | |
| Russian Federation | 9.159.2112 Boehringer Ingelheim Investigational Site | Volgograd | |
| Russian Federation | 9.159.2113 Boehringer Ingelheim Investigational Site | Volgograd | |
| Russian Federation | 9.159.2104 Boehringer Ingelheim Investigational Site | Voronezh | |
| Russian Federation | 9.159.2103 Boehringer Ingelheim Investigational Site | Yaroslavl | |
| Singapore | 9.159.2703 Boehringer Ingelheim Investigational Site | Singapore | |
| Singapore | 9.159.2704 Boehringer Ingelheim Investigational Site | Singapore | |
| Singapore | 9.159.2705 Boehringer Ingelheim Investigational Site | Singapore | |
| South Africa | 9.159.2060 Boehringer Ingelheim Investigational Site | Bloemfontein | |
| South Africa | 9.159.2056 Boehringer Ingelheim Investigational Site | Cape Town | |
| South Africa | 9.159.2057 Boehringer Ingelheim Investigational Site | Durban | |
| South Africa | 9.159.2055 Boehringer Ingelheim Investigational Site | Johannesburg | |
| South Africa | 9.159.2061 Boehringer Ingelheim Investigational Site | Johannesburg | |
| South Africa | 9.159.2058 Boehringer Ingelheim Investigational Site | Pretoria | |
| South Africa | 9.159.2059 Boehringer Ingelheim Investigational Site | Sunninghill | |
| Spain | 9.159.2179 Boehringer Ingelheim Investigational Site | Alicante | |
| Spain | 9.159.2177 Boehringer Ingelheim Investigational Site | Barcelona | |
| Spain | 9.159.2178 Boehringer Ingelheim Investigational Site | Hospitalet de Llobregat (Barcelona) | |
| Spain | 9.159.2175 Boehringer Ingelheim Investigational Site | Madrid | |
| Spain | 9.159.2176 Boehringer Ingelheim Investigational Site | Madrid | |
| Spain | 9.159.2180 Boehringer Ingelheim Investigational Site | Pamplona | |
| Sweden | 9.159.2223 Boehringer Ingelheim Investigational Site | Borås | |
| Sweden | 9.159.2209 Boehringer Ingelheim Investigational Site | Eskilstuna | |
| Sweden | 9.159.2204 Boehringer Ingelheim Investigational Site | Göteborg | |
| Sweden | 9.159.2205 Boehringer Ingelheim Investigational Site | Göteborg | |
| Sweden | 9.159.2728 Neurology Unit | Holon | |
| Sweden | 9.159.2210 Boehringer Ingelheim Investigational Site | Jönköping | |
| Sweden | 9.159.2206 Boehringer Ingelheim Investigational Site | Lund | |
| Sweden | 9.159.2211 Boehringer Ingelheim Investigational Site | Mora | |
| Sweden | 9.159.2208 Boehringer Ingelheim Investigational Site | Örebro | |
| Sweden | 9.159.2216 Boehringer Ingelheim Investigational Site | Skellefteå | |
| Sweden | 9.159.2215 Boehringer Ingelheim Investigational Site | Skövde | |
| Sweden | 9.159.2203 Boehringer Ingelheim Investigational Site | Stockholm | |
| Sweden | 9.159.2212 Boehringer Ingelheim Investigational Site | Stockholm | |
| Sweden | 9.159.2213 Boehringer Ingelheim Investigational Site | Stockholm | |
| Sweden | 9.159.2222 Boehringer Ingelheim Investigational Site | Stockholm | |
| Sweden | 9.159.2225 Boehringer Ingelheim Investigational Site | Stockholm | |
| Sweden | 9.159.2207 Boehringer Ingelheim Investigational Site | Umeå | |
| Sweden | 9.159.2214 Boehringer Ingelheim Investigational Site | Värnamo | |
| Sweden | 9.159.2224 Boehringer Ingelheim Investigational Site | Västervik | |
| Taiwan | 9.159.2250 Boehringer Ingelheim Investigational Site | Kaohsiung | |
| Taiwan | 9.159.2253 Boehringer Ingelheim Investigational Site | Kaohsiung | |
| Taiwan | 9.159.2248 Boehringer Ingelheim Investigational Site | Taichung | |
| Taiwan | 9.159.2249 Boehringer Ingelheim Investigational Site | Taichung | |
| Taiwan | 9.159.2251 Boehringer Ingelheim Investigational Site | Tainan | |
| Taiwan | 9.159.2244 Boehringer Ingelheim Investigational Site | Taipei | |
| Taiwan | 9.159.2245 Boehringer Ingelheim Investigational Site | Taipei | |
| Taiwan | 9.159.2246 Boehringer Ingelheim Investigational Site | Taipei | |
| Taiwan | 9.159.2247 Boehringer Ingelheim Investigational Site | Taipei | |
| Taiwan | 9.159.2252 Boehringer Ingelheim Investigational Site | Taipei | |
| Taiwan | 9.159.2254 Boehringer Ingelheim Investigational Site | Taipei | |
| Taiwan | 9.159.2243 Boehringer Ingelheim Investigational Site | Taoyuan | |
| Thailand | 9.159.2797 Boehringer Ingelheim Investigational Site | Bangkok | |
| Thailand | 9.159.2798 Boehringer Ingelheim Investigational Site | Bangkok | |
| Thailand | 9.159.2799 Boehringer Ingelheim Investigational Site | Bangkok | |
| Thailand | 9.159.2800 Boehringer Ingelheim Investigational Site | Bangkok | |
| Thailand | 9.159.2801 Boehringer Ingelheim Investigational Site | Chiang Mai | |
| Turkey | 9.159.2830 Boehringer Ingelheim Investigational Site | Ankara | |
| Turkey | 9.159.2829 Boehringer Ingelheim Investigational Site | Antalya | |
| Turkey | 9.159.2831 Boehringer Ingelheim Investigational Site | Bursa | |
| Turkey | 9.159.2827 Boehringer Ingelheim Investigational Site | Eskisehir | |
| Turkey | 9.159.2825 Boehringer Ingelheim Investigational Site | Istanbul | |
| Turkey | 9.159.2826 Boehringer Ingelheim Investigational Site | Istanbul | |
| Turkey | 9.159.2828 Dkuz Eylul Universitesi Tip Fakultesi Noroloji A.B.D. | Izmir | |
| Ukraine | 9.159.2387 Boehringer Ingelheim Investigational Site | Dnepropetrovsk | |
| Ukraine | 9.159.2384 Boehringer Ingelheim Investigational Site | Kharkiv | |
| Ukraine | 9.159.2385 Boehringer Ingelheim Investigational Site | Kharkiv | |
| Ukraine | 9.159.2386 Boehringer Ingelheim Investigational Site | Kharkiv | |
| Ukraine | 9.159.2392 Boehringer Ingelheim Investigational Site | Kharkiv | |
| Ukraine | 9.159.2379 Boehringer Ingelheim Investigational Site | Kyiv | |
| Ukraine | 9.159.2380 Boehringer Ingelheim Investigational Site | Kyiv | |
| Ukraine | 9.159.2382 Boehringer Ingelheim Investigational Site | Kyiv | |
| Ukraine | 9.159.2389 Boehringer Ingelheim Investigational Site | Odesa | |
| Ukraine | 9.159.2390 Boehringer Ingelheim Investigational Site | Odesa | |
| Ukraine | 9.159.2391 Boehringer Ingelheim Investigational Site | Vinnytzya | |
| Ukraine | 9.159.2388 Boehringer Ingelheim Investigational Site | Zaporizhzhya | |
| United Kingdom | 9.159.2304 Boehringer Ingelheim Investigational Site | Belfast | |
| United Kingdom | 9.159.2297 Boehringer Ingelheim Investigational Site | Birmingham | |
| United Kingdom | 9.159.2299 Boehringer Ingelheim Investigational Site | Bournemouth | |
| United Kingdom | 9.159.2301 Boehringer Ingelheim Investigational Site | Bristol | |
| United Kingdom | 9.159.2298 Boehringer Ingelheim Investigational Site | Dundee | |
| United Kingdom | 9.159.2307 Boehringer Ingelheim Investigational Site | Exeter | |
| United Kingdom | 9.159.2296 Boehringer Ingelheim Investigational Site | Glasgow | |
| United Kingdom | 9.159.2300 Boehringer Ingelheim Investigational Site | Glasgow | |
| United Kingdom | 9.159.2287 Boehringer Ingelheim Investigational Site | Harrow | |
| United Kingdom | 9.159.2303 Boehringer Ingelheim Investigational Site | Henshingham, Whitehaven | |
| United Kingdom | 9.159.2308 Boehringer Ingelheim Investigational Site | Leicester | |
| United Kingdom | 9.159.2295 Boehringer Ingelheim Investigational Site | Liverpool | |
| United Kingdom | 9.159.2286 Boehringer Ingelheim Investigational Site | London | |
| United Kingdom | 9.159.2293 Boehringer Ingelheim Investigational Site | London | |
| United Kingdom | 9.159.2294 Boehringer Ingelheim Investigational Site | London | |
| United Kingdom | 9.159.2305 Boehringer Ingelheim Investigational Site | Mansfield | |
| United Kingdom | 9.159.2290 Boehringer Ingelheim Investigational Site | Newcastle Upon Tyne | |
| United Kingdom | 9.159.2288 Boehringer Ingelheim Investigational Site | North Shields | |
| United Kingdom | 9.159.2285 Boehringer Ingelheim Investigational Site | Northampton | |
| United Kingdom | 9.159.2284 Boehringer Ingelheim Investigational Site | Nottingham | |
| United Kingdom | 9.159.2283 Boehringer Ingelheim Investigational Site | Poole | |
| United Kingdom | 9.159.2302 Boehringer Ingelheim Investigational Site | Rotherham | |
| United Kingdom | 9.159.2292 Boehringer Ingelheim Investigational Site | Sheffield | |
| United Kingdom | 9.159.2289 Boehringer Ingelheim Investigational Site | Southampton | |
| United Kingdom | 9.159.2306 Boehringer Ingelheim Investigational Site | Stoke on Trent | |
| United Kingdom | 9.159.2291 Boehringer Ingelheim Investigational Site | Sunderland | |
| United States | 9.159.1171 Boehringer Ingelheim Investigational Site | Abington | Pennsylvania |
| United States | 9.159.1159 Boehringer Ingelheim Investigational Site | Akron | Ohio |
| United States | 9.159.1086 Boehringer Ingelheim Investigational Site | Albany | New York |
| United States | 9.159.1170 Boehringer Ingelheim Investigational Site | Albuquerque | New Mexico |
| United States | 9.159.1210 Boehringer Ingelheim Investigational Site | Allentown | Pennsylvania |
| United States | 9.159.1214 Boehringer Ingelheim Investigational Site | Allentown | Pennsylvania |
| United States | 9.159.1099 Boehringer Ingelheim Investigational Site | Asheville | North Carolina |
| United States | 9.159.1071 Boehringer Ingelheim Investigational Site | Atlanta | Georgia |
| United States | 9.159.1079 Boehringer Ingelheim Investigational Site | Augusta | Georgia |
| United States | 9.159.1024 Boehringer Ingelheim Investigational Site | Baltimore | Maryland |
| United States | 9.159.1055 Boehringer Ingelheim Investigational Site | Baltimore | Maryland |
| United States | 9.159.1139 Boehringer Ingelheim Investigational Site | Baltimore | Maryland |
| United States | 9.159.1106 Boehringer Ingelheim Investigational Site | Baton Rouge | Louisiana |
| United States | 9.159.1057 Boehringer Ingelheim Investigational Site | Bay Pines | Florida |
| United States | 9.159.1040 Boehringer Ingelheim Investigational Site | Berkeley | California |
| United States | 9.159.1101 Boehringer Ingelheim Investigational Site | Birmingham | Alabama |
| United States | 9.159.1215 Boehringer Ingelheim Investigational Site | Bismarck | North Dakota |
| United States | 9.159.1217 Boehringer Ingelheim Investigational Site | Boca Raton | Florida |
| United States | 9.159.1189 Boehringer Ingelheim Investigational Site | Boise | Idaho |
| United States | 9.159.1031 Boehringer Ingelheim Investigational Site | Boston | Massachusetts |
| United States | 9.159.1066 Boehringer Ingelheim Investigational Site | Boston | Massachusetts |
| United States | 9.159.1104 Boehringer Ingelheim Investigational Site | Boston | Massachusetts |
| United States | 9.159.1166 Boehringer Ingelheim Investigational Site | Boston | Massachusetts |
| United States | 9.159.1003 Boehringer Ingelheim Investigational Site | Bountiful | Utah |
| United States | 9.159.1096 Boehringer Ingelheim Investigational Site | Bradenton | Florida |
| United States | 9.159.1006 Boehringer Ingelheim Investigational Site | Bristol | Tennessee |
| United States | 9.159.1121 Boehringer Ingelheim Investigational Site | Bronx | New York |
| United States | 9.159.1130 Boehringer Ingelheim Investigational Site | Bronx | New York |
| United States | 9.159.1017 Boehringer Ingelheim Investigational Site | Brooklyn | New York |
| United States | 9.159.1064 Boehringer Ingelheim Investigational Site | Brooklyn | New York |
| United States | 9.159.1186 Boehringer Ingelheim Investigational Site | Brooklyn | New York |
| United States | 9.159.1219 Boehringer Ingelheim Investigational Site | Brownwood | Texas |
| United States | 9.159.1151 Boehringer Ingelheim Investigational Site | Buffalo | New York |
| United States | 9.159.1204 Boehringer Ingelheim Investigational Site | Camden | New Jersey |
| United States | 9.159.1085 Boehringer Ingelheim Investigational Site | Canton | Ohio |
| United States | 9.159.1180 Boehringer Ingelheim Investigational Site | Carmichael | California |
| United States | 9.159.1027 Boehringer Ingelheim Investigational Site | Cedar Rapids | Iowa |
| United States | 9.159.1046 Boehringer Ingelheim Investigational Site | Chapel Hill | North Carolina |
| United States | 9.159.1211 Boehringer Ingelheim Investigational Site | Charleston | West Virginia |
| United States | 9.159.1026 University of Illinois | Chicago | Illinois |
| United States | 9.159.1033 Boehringer Ingelheim Investigational Site | Chicago | Illinois |
| United States | 9.159.1060 Boehringer Ingelheim Investigational Site | Chicago | Illinois |
| United States | 9.159.1032 Boehringer Ingelheim Investigational Site | Cincinnati | Ohio |
| United States | 9.159.1144 Boehringer Ingelheim Investigational Site | Clearwater | Florida |
| United States | 9.159.1025 Boehringer Ingelheim Investigational Site | Cleveland | Ohio |
| United States | 9.159.1177 Boehringer Ingelheim Investigational Site | Cleveland | Ohio |
| United States | 9.159.1140 Boehringer Ingelheim Investigational Site | Columbia | South Carolina |
| United States | 9.159.1008 Boehringer Ingelheim Investigational Site | Columbus | Ohio |
| United States | 9.159.1141 Boehringer Ingelheim Investigational Site | Columbus | Ohio |
| United States | 9.159.1181 Boehringer Ingelheim Investigational Site | Columbus | Georgia |
| United States | 9.159.1155 Boehringer Ingelheim Investigational Site | Dallas | Texas |
| United States | 9.159.1197 Boehringer Ingelheim Investigational Site | Dallas | Texas |
| United States | 9.159.1038 Boehringer Ingelheim Investigational Site | Danbury | Connecticut |
| United States | 9.159.1138 Boehringer Ingelheim Investigational Site | Decatur | Georgia |
| United States | 9.159.1118 Boehringer Ingelheim Investigational Site | Denver | Colorado |
| United States | 9.159.1119 Boehringer Ingelheim Investigational Site | Des Moines | Iowa |
| United States | 9.159.1187 Boehringer Ingelheim Investigational Site | Des Moines | Iowa |
| United States | 9.159.1019 Boehringer Ingelheim Investigational Site | Detroit | Michigan |
| United States | 9.159.1048 Boehringer Ingelheim Investigational Site | Detroit | Michigan |
| United States | 9.159.1089 Boehringer Ingelheim Investigational Site | Detroit | Michigan |
| United States | 9.159.1088 Boehringer Ingelheim Investigational Site | Duluth | Minnesota |
| United States | 9.159.1158 Boehringer Ingelheim Investigational Site | Duluth | Minnesota |
| United States | 9.159.1094 Boehringer Ingelheim Investigational Site | Durham | North Carolina |
| United States | 9.159.1078 Boehringer Ingelheim Investigational Site | East Lansing | Michigan |
| United States | 9.159.1203 Boehringer Ingelheim Investigational Site | Edison | New Jersey |
| United States | 9.159.1156 Boehringer Ingelheim Investigational Site | Elkhart | Indiana |
| United States | 9.159.1045 Boehringer Ingelheim Investigational Site | Englewood | Colorado |
| United States | 9.159.1200 Boehringer Ingelheim Investigational Site | Erie | Pennsylvania |
| United States | 9.159.1196 Boehringer Ingelheim Investigational Site | Fairfield | Connecticut |
| United States | 9.159.1152 Boehringer Ingelheim Investigational Site | Fargo | North Dakota |
| United States | 9.159.1184 Boehringer Ingelheim Investigational Site | Fayetteville | Arkansas |
| United States | 9.159.1005 Boehringer Ingelheim Investigational Site | Fort Smith | Arkansas |
| United States | 9.159.1007 Boehringer Ingelheim Investigational Site | Ft. Lauderdale | Florida |
| United States | 9.159.1084 Boehringer Ingelheim Investigational Site | Golden Valley | Minnesota |
| United States | 9.159.1143 Boehringer Ingelheim Investigational Site | Grand Rapids | Michigan |
| United States | 9.159.1146 Boehringer Ingelheim Investigational Site | Great Falls | Montana |
| United States | 9.159.1043 Boehringer Ingelheim Investigational Site | Greensburg | Pennsylvania |
| United States | 9.159.1207 Boehringer Ingelheim Investigational Site | Greenville | South Carolina |
| United States | 9.159.1018 Boehringer Ingelheim Investigational Site | Hartford | Connecticut |
| United States | 9.159.1164 Boehringer Ingelheim Investigational Site | Hershey | Pennsylvania |
| United States | 9.159.1012 Boehringer Ingelheim Investigational Site | High Point | North Carolina |
| United States | 9.159.1020 Boehringer Ingelheim Investigational Site | Houston | Texas |
| United States | 9.159.1023 Boehringer Ingelheim Investigational Site | Houston | Texas |
| United States | 9.159.1082 Boehringer Ingelheim Investigational Site | Houston | Texas |
| United States | 9.159.1160 Boehringer Ingelheim Investigational Site | Houston | Texas |
| United States | 9.159.1173 Boehringer Ingelheim Investigational Site | Huntsville | Alabama |
| United States | 9.159.1059 Boehringer Ingelheim Investigational Site | Iowa City | Iowa |
| United States | 9.159.1114 Boehringer Ingelheim Investigational Site | Irvine | California |
| United States | 9.159.1190 Boehringer Ingelheim Investigational Site | Jacksonville | Florida |
| United States | 9.159.1136 Boehringer Ingelheim Investigational Site | Jonesboro | Arkansas |
| United States | 9.159.1102 Boehringer Ingelheim Investigational Site | Kalamazoo | Michigan |
| United States | 9.159.1090 Boehringer Ingelheim Investigational Site | Kansas City | Kansas |
| United States | 9.159.1128 St. Luke's Hospital MABSI Research | Kansas City | Missouri |
| United States | 9.159.1154 Boehringer Ingelheim Investigational Site | Knoxville | Tennessee |
| United States | 9.159.1202 Boehringer Ingelheim Investigational Site | Laguna Hills | California |
| United States | 9.159.1175 Boehringer Ingelheim Investigational Site | Lancaster | Pennsylvania |
| United States | 9.159.1127 Boehringer Ingelheim Investigational Site | Las Vegas | Nevada |
| United States | 9.159.1172 Boehringer Ingelheim Investigational Site | Lees Summit | Missouri |
| United States | 9.159.1129 Central Baptis Hospital | Lexington | Kentucky |
| United States | 9.159.1131 Boehringer Ingelheim Investigational Site | Lexington | Kentucky |
| United States | 9.159.1206 Boehringer Ingelheim Investigational Site | Lexington | Kentucky |
| United States | 9.159.1212 Boehringer Ingelheim Investigational Site | Lexington | Kentucky |
| United States | 9.159.1062 Boehringer Ingelheim Investigational Site | Little Rock | Arkansas |
| United States | 9.159.1036 Boehringer Ingelheim Investigational Site | Los Angeles | California |
| United States | 9.159.1052 Boehringer Ingelheim Investigational Site | Los Angeles | California |
| United States | 9.159.1100 Boehringer Ingelheim Investigational Site | Los Angeles | California |
| United States | 9.159.1111 Boehringer Ingelheim Investigational Site | Los Angeles | California |
| United States | 9.159.1165 Boehringer Ingelheim Investigational Site | Los Angeles | California |
| United States | 9.159.1091 Boehringer Ingelheim Investigational Site | Louisville | Kentucky |
| United States | 9.159.1147 Boehringer Ingelheim Investigational Site | Louisville | Kentucky |
| United States | 9.159.1042 Neurology Consultants of Burlington County | Lumberton | New Jersey |
| United States | 9.159.1076 North Shore University Hospital | Manasset | New York |
| United States | 9.159.1194 Boehringer Ingelheim Investigational Site | Marrero | Louisiana |
| United States | 9.159.1030 Boehringer Ingelheim Investigational Site | Marshfield | Wisconsin |
| United States | 9.159.1044 Boehringer Ingelheim Investigational Site | Maywood | Illinois |
| United States | 9.159.1213 Boehringer Ingelheim Investigational Site | Memphis | Tennessee |
| United States | 9.159.1117 Boehringer Ingelheim Investigational Site | Milwaukee | Wisconsin |
| United States | 9.159.1037 Boehringer Ingelheim Investigational Site | Mineola | New York |
| United States | 9.159.1097 Boehringer Ingelheim Investigational Site | Minneapolis | Minnesota |
| United States | 9.159.1113 Boehringer Ingelheim Investigational Site | Minneapolis | Minnesota |
| United States | 9.159.1058 Boehringer Ingelheim Investigational Site | Mobile | Alabama |
| United States | 9.159.1087 Boehringer Ingelheim Investigational Site | Montgomery | Alabama |
| United States | 9.159.1035 Boehringer Ingelheim Investigational Site | Morgantown | West Virginia |
| United States | 9.159.1075 Boehringer Ingelheim Investigational Site | Nashville | Tennessee |
| United States | 9.159.1209 Boehringer Ingelheim Investigational Site | New Brunswick | New Jersey |
| United States | 9.159.1220 Boehringer Ingelheim Investigational Site | New Hyde Park | New York |
| United States | 9.159.1083 Boehringer Ingelheim Investigational Site | New Orleans | Louisiana |
| United States | 9.159.1001 Boehringer Ingelheim Investigational Site | New York | New York |
| United States | 9.159.1116 Boehringer Ingelheim Investigational Site | New York | New York |
| United States | 9.159.1142 Saint Luke's-Roosevelt Hospital | New York | New York |
| United States | 9.159.1080 Boehringer Ingelheim Investigational Site | Newark | Delaware |
| United States | 9.159.1125 Boehringer Ingelheim Investigational Site | Newark | New Jersey |
| United States | 9.159.1077 Boehringer Ingelheim Investigational Site | Newport News | Virginia |
| United States | 9.159.1081 Boehringer Ingelheim Investigational Site | Northport | Alabama |
| United States | 9.159.1150 Boehringer Ingelheim Investigational Site | Ocala | Florida |
| United States | 9.159.1134 Boehringer Ingelheim Investigational Site | Oceanside | California |
| United States | 9.159.1199 Boehringer Ingelheim Investigational Site | Oklahoma City | Oklahoma |
| United States | 9.159.1201 Boehringer Ingelheim Investigational Site | Omaha | Nebraska |
| United States | 9.159.1002 Boehringer Ingelheim Investigational Site | Palo Alto | California |
| United States | 9.159.1054 Boehringer Ingelheim Investigational Site | Palos Heights | Illinois |
| United States | 9.159.1153 Boehringer Ingelheim Investigational Site | Panama City | Florida |
| United States | 9.159.1068 Boehringer Ingelheim Investigational Site | Park Ridge | Illinois |
| United States | 9.159.1178 Boehringer Ingelheim Investigational Site | Peoria | Illinois |
| United States | 9.159.1016 Boehringer Ingelheim Investigational Site | Philadelphia | Pennsylvania |
| United States | 9.159.1056 Boehringer Ingelheim Investigational Site | Philadelphia | Pennsylvania |
| United States | 9.159.1074 Boehringer Ingelheim Investigational Site | Philadelphia | Pennsylvania |
| United States | 9.159.1022 Boehringer Ingelheim Investigational Site | Phoenix | Arizona |
| United States | 9.159.1133 Boehringer Ingelheim Investigational Site | Phoenix | Arizona |
| United States | 9.159.1149 Boehringer Ingelheim Investigational Site | Phoenix | Arizona |
| United States | 9.159.1112 Boehringer Ingelheim Investigational Site | Pittsburgh | Pennsylvania |
| United States | 9.159.1041 Boehringer Ingelheim Investigational Site | Plantation | Florida |
| United States | 9.159.1072 Boehringer Ingelheim Investigational Site | Port Charlotte | Florida |
| United States | 9.159.1010 Boehringer Ingelheim Investigational Site | Portland | Oregon |
| United States | 9.159.1123 Boehringer Ingelheim Investigational Site | Providence | Rhode Island |
| United States | 9.159.1108 Boehringer Ingelheim Investigational Site | Redding | California |
| United States | 9.159.1188 Boehringer Ingelheim Investigational Site | Reno | Nevada |
| United States | 9.159.1021 Boehringer Ingelheim Investigational Site | Richmond | Virginia |
| United States | 9.159.1095 Boehringer Ingelheim Investigational Site | Ridgewood | New Jersey |
| United States | 9.159.1070 Boehringer Ingelheim Investigational Site | Rome | Georgia |
| United States | 9.159.1013 Boehringer Ingelheim Investigational Site | Sacramento | California |
| United States | 9.159.1198 Boehringer Ingelheim Investigational Site | Sacramento | California |
| United States | 9.159.1011 Boehringer Ingelheim Investigational Site | Saginaw | Michigan |
| United States | 9.159.1174 Boehringer Ingelheim Investigational Site | Saint Louis | Missouri |
| United States | 9.159.1061 Boehringer Ingelheim Investigational Site | Salem | Virginia |
| United States | 9.159.1047 Boehringer Ingelheim Investigational Site | San Antonio | Texas |
| United States | 9.159.1029 Boehringer Ingelheim Investigational Site | San Diego | California |
| United States | 9.159.1185 Boehringer Ingelheim Investigational Site | San Francisco | California |
| United States | 9.159.1218 Boehringer Ingelheim Investigational Site | San Jose | California |
| United States | 9.159.1179 Boehringer Ingelheim Investigational Site | Santa Rosa | California |
| United States | 9.159.1063 Boehringer Ingelheim Investigational Site | Sarasota | Florida |
| United States | 9.159.1107 Boehringer Ingelheim Investigational Site | Savannah | Georgia |
| United States | 9.159.1126 Boehringer Ingelheim Investigational Site | Schenectady | New York |
| United States | 9.159.1014 Boehringer Ingelheim Investigational Site | Seattle | Washington |
| United States | 9.159.1195 Boehringer Ingelheim Investigational Site | Shreveport | Louisiana |
| United States | 9.159.1092 Boehringer Ingelheim Investigational Site | South Bend | Indiana |
| United States | 9.159.1192 Boehringer Ingelheim Investigational Site | South Weymouth | Massachusetts |
| United States | 9.159.1132 Boehringer Ingelheim Investigational Site | Southfield | Michigan |
| United States | 9.159.1004 Boehringer Ingelheim Investigational Site | Spartanberg | South Carolina |
| United States | 9.159.1145 Boehringer Ingelheim Investigational Site | Spokane | Washington |
| United States | 9.159.1009 Boehringer Ingelheim Investigational Site | Springfield | Missouri |
| United States | 9.159.1182 Boehringer Ingelheim Investigational Site | St. Louis | Missouri |
| United States | 9.159.1191 Boehringer Ingelheim Investigational Site | St. Louis | Missouri |
| United States | 9.159.1163 Boehringer Ingelheim Investigational Site | Stony Brook | New York |
| United States | 9.159.1162 Boehringer Ingelheim Investigational Site | Sylmar | California |
| United States | 9.159.1208 Boehringer Ingelheim Investigational Site | Tampa | Florida |
| United States | 9.159.1053 Boehringer Ingelheim Investigational Site | Toledo | Ohio |
| United States | 9.159.1169 Boehringer Ingelheim Investigational Site | Tonawanda | New York |
| United States | 9.159.1183 Boehringer Ingelheim Investigational Site | Torrance | California |
| United States | 9.159.1137 Boehringer Ingelheim Investigational Site | Tucson | Arizona |
| United States | 9.159.1069 Boehringer Ingelheim Investigational Site | Tyler | Texas |
| United States | 9.159.1148 Boehringer Ingelheim Investigational Site | Upland | Pennsylvania |
| United States | 9.159.1049 Boehringer Ingelheim Investigational Site | Vero Beach | Florida |
| United States | 9.159.1205 Boehringer Ingelheim Investigational Site | Walnut Creek | California |
| United States | 9.159.1120 Boehringer Ingelheim Investigational Site | Washington | District of Columbia |
| United States | 9.159.1216 Boehringer Ingelheim Investigational Site | Washington | District of Columbia |
| United States | 9.159.1135 Boehringer Ingelheim Investigational Site | Waterloo | Iowa |
| United States | 9.159.1098 Community Healthcare Clinic Westhill Medical Specialists | Wausau | Wisconsin |
| United States | 9.159.1176 Boehringer Ingelheim Investigational Site | West Palm Beach | Florida |
| United States | 9.159.1065 Boehringer Ingelheim Investigational Site | White Plains | New York |
| United States | 9.159.1115 | Wilmington | North Carolina |
| United States | 9.159.1051 Boehringer Ingelheim Investigational Site | Winston-Salem | North Carolina |
| United States | 9.159.1110 Boehringer Ingelheim Investigational Site | Winston-Salem | North Carolina |
| United States | 9.159.1039 Boehringer Ingelheim Investigational Site | Worchester | Massachusetts |
| United States | 9.159.1122 Boehringer Ingelheim Investigational Site | Youngstown | Ohio |
| Lead Sponsor | Collaborator |
|---|---|
| Boehringer Ingelheim | Bayer, GlaxoSmithKline |
United States, Argentina, Australia, Austria, Belgium, Brazil, Canada, China, Denmark, El Salvador, Finland, France, Germany, Greece, Hong Kong, India, Ireland, Israel, Italy, Japan, Korea, Republic of, Malaysia, Mexico, Netherlands, Norway, Portugal, Russian Federation, Singapore, South Africa, Spain, Sweden, Taiwan, Thailand, Turkey, Ukraine, United Kingdom,
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | Number of Patients With First Recurrent Stroke of Any Type, Fatal or Nonfatal (Antiplatelet Comparison Only) | time since randomization; follow-up period is 1.5 to 4.4 years | ||
| Primary | Number of Patients With First Recurrent Stroke of Any Type, Fatal or Nonfatal (Telmisartan vs. Placebo Only) | time since randomization; follow-up period is 1.5 to 4.4 years | ||
| Secondary | Composite Outcome of Stroke, Myocardial Infarction (MI), or Vascular Death (Antiplatelet Comparison Only) | Number of patients with any of stroke, myocardial infarction, vascular death | time since randomization; follow-up period is 1.5 to 4.4 years | |
| Secondary | Composite Outcome of Stroke, Myocardial Infarction, Vascular Death, or New or Worsening Congestive Heart Failure (CHF) (Telmisartan vs. Placebo Only) | Number of patients with any of stroke, myocardial infarction, vascular death, or new or worsening congestive heart failure | time since randomization; follow-up period is 1.5 to 4.4 years | |
| Secondary | Number of Patients With New Onset of Diabetes (Telmisartan vs. Placebo Only) | Randomization to final patient contact |
| Status | Clinical Trial | Phase | |
|---|---|---|---|
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