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Stroke Sequelae clinical trials

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NCT ID: NCT06208059 Completed - Movement Disorders Clinical Trials

Electroacupuncture of Scalp Motor Area to Improve Post-Stroke Wrist Dyskinesia

Start date: July 1, 2021
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to compare the clinical efficacy of electroacupuncture and manual acupuncture in stimulating the scalp motor area for treating post-stroke wrist dyskinesia and its influence on the function of wrist movement-related active muscles. The main question it aims to answer is: which method of stimulating the scalp motor area is more effective in the recovery of wrist motor function after stroke? Participants will be given routine Western medicine treatment and acupuncture treatment on the hemiplegic side. In the manual acupuncture group, participants will be needled in the scalp motor area on the lesion side. The same acupoint was selected as the manual acupuncture group in the electroacupuncture group. The score of Chinese Stroke Scale (CSS), the score of the upper limb of the Barthel Index (BI), the active range of motion (AROM) of wrist joint, and the surface electromyography (sEMG) was used to measure the root mean square (RMS) of extensor carpi radialis longus, extensor digitorum, flexor carpi radialis and flexor carpi ulnaris on the hemiplegic side of the patients before and after the 3-week treatment period, respectively compare the clinical efficacy of the two groups.

NCT ID: NCT06090474 Completed - Stroke Clinical Trials

Multiple Dose Study to Evaluate Drug-drug Interactions, Safety and Tolerability of NDC-002 in Healthy Volunteers

Start date: January 12, 2023
Phase: Phase 1
Study type: Interventional

An Open-label, One-sequence, Three-period, Multiple-dose Study to Evaluate Drug-drug Interactions, Safety and Tolerability between NDC-002A/NDC-002B and NDC-002C in Healthy Volunteers

NCT ID: NCT06061731 Completed - Stroke Sequelae Clinical Trials

Low-frequency Electrical Stimulation of Acupuncture Points

Start date: January 1, 2022
Phase: Early Phase 1
Study type: Interventional

Abstract: Objective: To examine the effect of low-frequency acupoint electrical stimulation (LFES) on the surface electromyographic (sEMG) signals of the thumb-to-finger movement muscles in stroke patients, and to evaluate the clinical efficacy of LFES on hand function recovery after stroke.

NCT ID: NCT05792605 Completed - Stroke Sequelae Clinical Trials

ATFL Evaluation With Ultrasound in Stroke Patients

ATFL
Start date: February 20, 2023
Phase:
Study type: Observational

ATFL thickness increases on the affected side of stroke patients and the homogeneous fibrillar structure is deteriorated.We aim to compare morphology of ATFL and Achilles tendon on the affected and unaffected sides using ultrasound in hemiplegic patients.

NCT ID: NCT05333497 Completed - Movement Disorders Clinical Trials

Programmed Flexor-extensor Alternating Electrical Acupiont Stimulation on Limb Functional Reconstruction After Stroke

Start date: April 18, 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to study the effect mechanism of programmed flexor-extensor alternating electrical acupiont stimulation on upper limb functional reconstruction after stroke.

NCT ID: NCT05330988 Completed - Stroke Clinical Trials

Post-stroke Fatigue, Inflammation, tDCS

Start date: July 12, 2022
Phase: N/A
Study type: Interventional

Fatigue is a common condition after an individual has a stroke. While the negative impacts of post-stroke fatigue are well known, the knowledge of the causes of post-stroke fatigue and effective treatments for post-stroke fatigue are lacking. This small study will investigate the possible benefits of transcranial direct current stimulation (tDCS), which uses small electrical currents supplied by a 9-volt battery, on post-stroke fatigue and investigate tDCS' possible anti-inflammatory effects.

NCT ID: NCT04851756 Completed - Spasticity, Muscle Clinical Trials

Effects of CRet Associated With Functional Massage (F.M) on Gait and Functionality in Post-stroke Spasticity

Start date: April 29, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to assess the immediate effects of CRet associated to Functional Massage (F.M) in terms of gait and functionality after stroke

NCT ID: NCT04824768 Completed - Spasticity, Muscle Clinical Trials

Effect of Tecar in Addition of Functional Massage in Post-stroke Spasticity

Tecar
Start date: May 20, 2021
Phase: N/A
Study type: Interventional

Spasticity is due to an abnormal processing of a normal input from muscle spindles in the spinal cord.

NCT ID: NCT04721574 Completed - Stroke Sequelae Clinical Trials

Bright Light Therapy on Post-stroke Insomniawith Post-stroke Insomnia

Start date: August 1, 2016
Phase: N/A
Study type: Interventional

The objective of this study was to determine the effectiveness of bright light therapy as a treatment for early, mild-to-moderate stroke patients with post-stroke insomnia.

NCT ID: NCT04713384 Completed - Depression Clinical Trials

Remote Bimanual Virtual Rehabilitation Post CVD

Start date: September 30, 2015
Phase: N/A
Study type: Interventional

The aim of the study is to develop the BrightBrainer G (grasp), a game-based upper-extremity motor and cognitive rehabilitation system using custom virtual reality simulations. The G model is a version of the BrightBrainer Rehabilitation System, a Class 1 Exempt medical device produced by Bright Cloud International Corp (FDA owner/operator 10050478), and listed with the FDA (registration number 3012187972);