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Stroke, Cardiovascular clinical trials

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NCT ID: NCT06303050 Recruiting - Clinical trials for Stroke, Cardiovascular

Additional Effects of Mental Imagery Along With Task Oriented Training on Kinesiophobia in Patients With Stroke

Start date: December 7, 2023
Phase: N/A
Study type: Interventional

The objective of this study to determine the effect of mental imagery and task oriented training on Kinesiophobia in stroke patients. And to determine the association of Kinesiophobia with gait and balance in stroke patients. Patients will be divided into experimental and control group. Randomized participants will be allocated into control and experimental group. The experimental group will receive 20 minutes of MI training followed by 25 minutes of TOT for a total of 45 minutes, 5 days per week for 6 weeks.

NCT ID: NCT05745051 Recruiting - Stroke Clinical Trials

The Safety and Effectiveness of CVA-FLOW Software Device for Acute Ischemic Stroke

Start date: November 8, 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to demonstrate the effectiveness and safety of CVA-FLOW, a digital health AI based Telestroke system developed by CVAID Ltd. Company aims to assist certified medical staff to triage acute ischemic stroke patients using dedicated algorithms in order to support application for market approval for CVA-FLOW device.

NCT ID: NCT05414539 Completed - Clinical trials for Cognitive Impairment

OptiCogs: A Multicomponent Intervention to Rehabilitate Cognitive Impairment in People Post-stroke

Start date: May 9, 2022
Phase: N/A
Study type: Interventional

OptiCogs Online is a complex multicomponent intervention comprising of cognitive, physical activity and educational components.

NCT ID: NCT05333146 Recruiting - Clinical trials for Cardiovascular Diseases

Outcomes After Perioperative Stroke Following Cardiac Surgery

Start date: April 18, 2022
Phase:
Study type: Observational

Perioperative stroke is a devastating complication of cardiac surgery that is currently poorly characterized but occurs in 1-5% of patients and is associated with poor outcomes including increased mortality. Given the uncommon nature of this complication, relatively little is known about which factors predict these outcomes among those who experience a perioperative stroke. The study objectives are to identify predictors of mortality, length of stay and discharge disposition after perioperative stroke in cardiac surgery using the prospectively-collected American College of Surgeons National Surgical Quality Improvement Program database between 2005 and 2020.

NCT ID: NCT05289947 Recruiting - Stroke Clinical Trials

MLC1501 Study Assessing Efficacy in Post STrOke Subjects With mOtor Deficits

MAESTOSO
Start date: July 21, 2023
Phase: Phase 2
Study type: Interventional

This is a multi-center, randomized, double-blind, placebo-controlled trial of MLC1501 in patients with stroke. Eligible participants will be randomized in a 1:1:1 ratio to orally receive MLC1501 high-dose twice a day, MLC1501 low-dose twice a day, or matching placebo for 24 weeks.

NCT ID: NCT05058586 Completed - Clinical trials for Stroke, Cardiovascular

The Effects of Aerobic Exercise Training on Cardiorespiratory Fitness in Stroke Patients

Start date: July 1, 2017
Phase: N/A
Study type: Interventional

Background: Aerobic exercise training has favorable effects on quality of life, motor recovery, and aerobic endurance after stroke. Objectives: In this study, the investigators aimed to explore the effects of anti-gravity treadmill gait training and underwater walking therapy on cardiorespiratory fitness in stroke survivors.

NCT ID: NCT05046106 Not yet recruiting - Stroke Clinical Trials

MLC1501 Study Assessing Efficacy in STROke Recovery

MAEStro
Start date: January 2025
Phase: Phase 2/Phase 3
Study type: Interventional

This is a multi-center, randomized, double-blind, placebo-controlled, dose-response study of MLC1501 in patients with stroke. Eligible participants will be randomized in a 1:1:1 ratio to orally receive MLC1501 low-dose twice a day, MLC1501 high-dose twice a day, or matching placebo for 24 weeks.

NCT ID: NCT05008822 Completed - Clinical trials for Stroke, Cardiovascular

Effect of Motor Imaginary Training on Upper Limb Functions in Stroke

Start date: October 1, 2021
Phase: N/A
Study type: Interventional

This study will provide knowledge about effectiveness of motor imaginary training in upper limb performance in chronic stroke patients. Very little data is available about the use in Motor Imaginary in post stroke upper limb rehabilitation in Pakistan. Moreover, studies done previously did not specified population of stroke; This study will include MCA stroke patients only, whom upper limb weakness is more prevalent.

NCT ID: NCT04989920 Completed - Clinical trials for Stroke, Cardiovascular

Brain and Behavior Correlates of Arm Rehabilitation

BCAR
Start date: April 28, 2003
Phase: N/A
Study type: Interventional

This project is designed to use three-dimensional movement analysis and magnetic resonance (fMRI) neuroimaging techniques to examine the brain activity and motor behavior changes associated with constraint-induced (CI) therapy for patients with sub-acute stroke (3-9 months post-stroke).Participants are evaluated at 5 time points-1-mo (pre & post), 6-mo (pre & post), and 12-mo. Each person is randomized to receive CI therapy either between pre- and post-evaluations or after the 6-mo pre-evaluation. We will determine the effects of CI therapy on 1) reaching and grasping actions using behavioral kinematics and 2) the sensorimotor network through fMRI scans with goal-directed aiming and grasping tasks. We will also determine the relationship between lesion size and location using 3-D volumetric MRI scans and behavioral outcomes as a consequence of CI therapy.

NCT ID: NCT04777955 Completed - Clinical trials for Stroke, Cardiovascular

The Effects of Core Stabilization Exercises With Swisball in Stroke Patients

Start date: May 4, 2021
Phase: N/A
Study type: Interventional

Stroke is often associated with secondary complications such as nutritional and metabolic disorders, endocrine dysfunction, mental problems, and cardiopulmonary disorders caused by neurological and musculoskeletal deficits. The absence of the paretic side muscles and the difficulty of movement together with restrictive pulmonary disorders trigger a secondary decrease in cardiopulmonary function and expose insufficient energy associated with gait resulting in a decrease in asymmetric trunk exercise endurance.