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Stress, Physiological clinical trials

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NCT ID: NCT06423053 Active, not recruiting - Mindfulness Clinical Trials

Mindful Physiology: A College Biology Course With Integrated Mindfulness

Start date: March 21, 2024
Phase: N/A
Study type: Interventional

The proposed study aims to evaluate whether integrating mindfulness practice into an undergraduate biology course influences student levels of mindfulness, stress, positive academic emotions, and physical, mental, and social health outcomes. These outcomes will be evaluated for students who enroll in the biology course compared to students who attempted to register but were put on a waitlist (waitlisted).

NCT ID: NCT05523414 Active, not recruiting - Anxiety Clinical Trials

The Effect of SKY Breath Meditation on Health and Well-being

Start date: April 1, 2023
Phase: N/A
Study type: Interventional

The goal of this pilot SKY (Sudarshan Kriya Yoga) Breath Meditation study is to establish feasibility and acceptability of the intervention; and investigate preliminary effectiveness of the intervention at the DNA methylation, RNA and protein levels in blood samples collected from participants before and after the 8 week SKY intervention. Primary outcomes also include preliminary effectiveness at the physiological level using a wearable device used for continuous monitoring. Secondary outcome measures include behavioral inventories.

NCT ID: NCT03904979 Active, not recruiting - Clinical trials for Pregnancy Complications

Therapeutic Writing to Reduce Stress

RESeT
Start date: October 22, 2019
Phase: N/A
Study type: Interventional

Purpose: The investigators hypothesize that exposure to chronic environmental stress is a risk factor for adverse pregnancy outcomes related to preterm birth and preeclampsia among high-risk pregnant women. Additionally, the investigators hypothesize that women can be screened for high levels of environmental stress through the perceived stress scale, and therapeutic writing can be used as a low-resource intervention to help decrease maternal perceived stress and inflammation - measured through analysis of maternal serum and placental samples. Participants: Pregnant women at high risk for adverse pregnancy outcomes, including pre-eclampsia and preterm birth, enrolled in prenatal care at UNC will be recruited for participation Procedures: Using results from the perceived stress scale, the investigators will identify women who screen positive for high environmental stress. Women meeting inclusion criteria will be contacted for possible participation at regularly scheduled prenatal visits. Women who are enrolled will be randomized to generalized writing prompts, therapeutic writing prompts, or no writing during their pregnancy to be administered at each prenatal visit. Maternal blood sample for biochemical markers of stress and gene expression will be obtained at the initial visit; a followup blood sample will be obtained later in pregnancy, and a small portion of the placenta saved at delivery. Delivery outcomes will be obtained through medical record review.

NCT ID: NCT03412162 Active, not recruiting - Clinical trials for Stress, Psychological

Biology, Identity & Opportunity Study

BIO
Start date: December 16, 2017
Phase: N/A
Study type: Interventional

This study will implement an intervention designed to promote ethnic and racial identity development. It is hypothesized that the intervention will have positive effects on ethnic-racial identity development, stress biology (including sleep hours and quality and diurnal cortisol profiles), emotional well-being, executive functioning, and academic outcomes, particularly for minority youth.

NCT ID: NCT02339506 Active, not recruiting - Clinical trials for Stress, Physiological

Stress and the Nervous System

Start date: April 2015
Phase: N/A
Study type: Interventional

Models of stress such as hypoglycemia have identified that stress results the next day in decreased baroreflex sensitivity. This project will test the hypothesis that these delayed changes in autonomic nervous system function are secondary to a rise in ACTH. The investigators will infuse cosyntropin versus placebo in a double-blind, crossover study in healthy adults and measure the delayed effects on the autonomic system as measured by cardiovagal baroreflex sensitivity.

NCT ID: NCT02140307 Active, not recruiting - Quality of Life Clinical Trials

Relaxation-Response-based Mental Health Promotion - Open and Calm 2013

RR-MHP OC13
Start date: January 2013
Phase: N/A
Study type: Interventional

The purpose of the study is to investigate health-promoting and stress-reducing psychological, physiological and hormonal effects of a 9-week meditation-based course in personal health and to examine potential baseline factors for any such effects. Thus, the investigators will investigate the course format (individual course or group-based course) as a potential factor the course outcome, and also individual background factors such as demographics and genetic variations.