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Stress Disorders clinical trials

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NCT ID: NCT01717547 Completed - Stress Disorders Clinical Trials

Strength and Awareness in Action

Start date: June 2012
Phase: N/A
Study type: Interventional

The aims of this research study are to 1) assess the acceptability and feasibility of conducting a yoga-based intervention for Veterans receiving care at a Veterans Affairs Medical Center, and 2) obtain preliminary data regarding the effect of the intervention on Veteran's mental health.

NCT ID: NCT01667822 Completed - Anxiety Disorders Clinical Trials

Cognitive Behavioral Therapy, Guided Self Help Versus Individual Therapy

Start date: August 2012
Phase: Phase 3
Study type: Interventional

Background: Studies show that about 1 out of 3 patients in Primary Care suffer primarily from mental health disorders, such as anxiety disorders and depression. Cognitive behavior therapy (CBT) has been shown to be an effective treatment of these disorders. Despite the strong evidence for CBT there is a lack of evidence-based psychological treatment in primary care. For various reasons, the progress of research has not affected clinical practice. For successful implementation of CBT in primary care cost-effective therapies, access to therapists with proper training and supervision, evidence-based manuals and management that support the implementation is needed. Aim: The aim of this trial is to evaluate a stepped care model with CBT in primary care. All patients are first treated with self-help CBT (N = 400). Patients that do not improve after treatment (9 weeks) are randomized to individual CBT or continued self-help treatment. Based on published studies 2/3 is expected to be improved after self-help and therefore do not undergo randomization. 1/3 (n = 133) who didn´t respond to treatment is randomized to individual CBT (N = 67) or continued self-help treatment (N = 67).

NCT ID: NCT01667809 Completed - Anxiety Disorders Clinical Trials

CBT vs RTW Intervention for Patients With Common Subclinical Mental Illness in Primary Care

Start date: August 2012
Phase: Phase 3
Study type: Interventional

Background: Common mental illness, such as anxiety disorders and depression, is the main cause for sick leave in Sweden. Cognitive behavior therapy (CBT) has been shown to be effective in alleviating target symptoms of these disorders, but its effect on sick leave rates has not been sufficiently addressed. The investigators have developed an intervention called return to work (RTW), which is based in cognitive behavioral theory, that has a primary aim of helping sick-listed patients with common mental illness return to work. This new treatment has not been evaluated in a randomized controlled trial. Aims: The aim of this study is to investigate the effect of CBT and RTW for subclinical common mental illness in a randomized controlled trial conducted in primary care. Participants will be randomized to diagnosis specific CBT (n=50), RTW (n=50. Main outcomes are days of sick leave and clinician severity rating of psychiatric symptoms. This study could contribute to new knowledge regarding how to best treat patients on sick leave with mild common mental illness.

NCT ID: NCT01636791 Completed - Anxiety Disorders Clinical Trials

CBT Versus a Return to Work Intervention for Patients With Common Mental Illness in Primary Care

CBT vs RTW I
Start date: September 2012
Phase: Phase 3
Study type: Interventional

Background: Common mental illness, such as anxiety disorders and depression, is the main cause for sick leave in Sweden. Cognitive behavior therapy (CBT) has been shown to be effective in alleviating target symptoms of these disorders, but its effect on sick leave rates has not been sufficiently addressed. The investigators have developed an intervention called return to work (RTW), which is based in cognitive behavioral theory, that has a primary aim of helping sick-listed patients with common mental illness return to work. This new treatment has not been evaluated in a randomized controlled trial. Aims: The aim of this study is to investigate the effect of CBT and RTW for common mental illness in a randomized controlled trial conducted in primary care. Participants will be randomized to diagnosis specific CBT (n=70), RTW (n=70), or a combination of the two treatments (n=70). Main outcomes are days of sick leave and clinician severity rating of psychiatric symptoms. This study could contribute to new knowledge regarding how to best treat patients on sick leave with common mental illness.

NCT ID: NCT01565213 Completed - Anxiety Disorders Clinical Trials

Transdiagnostic Group Treatments for Patients With Common Mental Disorders in Primary Health Care

Start date: January 2006
Phase: Phase 3
Study type: Interventional

The purpose of this study is to compare the effects of CBT and MMI on the quality of life and relief of psychological symptoms of patients with common mental disorders or problems attending primary health care centre.

NCT ID: NCT01538082 Recruiting - Metabolic Syndrome Clinical Trials

Role of the Stress in the Development of the Metabolic Syndrome

STREX
Start date: December 2008
Phase: N/A
Study type: Observational

The purpose of this study is determine the incidence of metabolic syndrome (MetS) in people of high risk, of 40 or more years and attended in the Primary Care. Evaluating the association between anxiety, depression, quality of life and the vital stressful events, and the development of the metabolic syndrome in general population. Our hypothesis is that population of the cohort with bigger degree of stress will develop earlier the metabolic syndrome. If our hypothesis about the metabolic syndrome are demonstrated, it would allow establishing in a future interventions on these factors of risk to prevent or to decrease the incidence of this syndrome in the Primary Care.

NCT ID: NCT01459705 Completed - Clinical trials for Post-Traumatic Stress Disorder

Comparing Virtual Reality Exposure Therapy to Prolonged Exposure

VRPE Extension
Start date: October 2011
Phase: N/A
Study type: Interventional

This study is evaluating the efficacy of virtual reality exposure therapy (VRET) by comparing it to prolonged exposure therapy (PE) and a waitlist(WL) group for the treatment of post traumatic stress disorder (PTSD) in active duty (AD) Soldiers with combat-related trauma. The investigators will test the general hypothesis that 10 sessions of VRET or PE will successfully treat PTSD, therapeutically affect levels of physiological arousal, and significantly reduce perceptions of stigma toward seeking behavioral health services.

NCT ID: NCT01277354 Completed - Depression Clinical Trials

Effectiveness of Cognitive Processing Therapy in Pregnant Women With a History of Pregnancy Loss/Complication

Start date: April 2010
Phase: N/A
Study type: Interventional

The purpose of this study is to examine the effects of experiencing a previous pregnancy loss or complication on current physiological and emotional aspects of a current pregnancy.

NCT ID: NCT01216982 Active, not recruiting - Depression Clinical Trials

Effects of Omega-3 EPA/DHA for Soldiers at Risk for Mood Disorders

Start date: November 2010
Phase: Phase 2
Study type: Interventional

Stress-related disorders are among the most prevalent and expensive medical consequences of participation in military operations. Omega-3 fatty acids EPA/DHA derived from fish oil are known to benefit both neuronal development in the young, and cognition and mood in various populations. It is possible that soldiers receiving Omega-3 EPA/DHA will exhibit significantly higher cognitive performance, better affect/mood state, and less combat stress symptomatology compared to the placebo after 12 weeks of supplementation. A goal would be to reduce the prevalence of combat stress injuries in military personnel.

NCT ID: NCT01062022 Terminated - Combat Disorders Clinical Trials

FOCUS-CI: A Preventive Intervention With Children and Families of the Combat Injured

FOCUS-CI
Start date: January 2011
Phase: N/A
Study type: Interventional

The purpose of this study is to implement a unique evidence-based intervention program to help military families deal with the critical issue of combat injury and its impact on current and future family health and functioning. The study is a randomized study. The study will compare the effects of the newly designed FOCUS-CI (Families OverComing Under Stress - Combat Injury) with the existing standard of care (SoC) at three military medical rehabilitation sites (Walter Reed Amry Medical Center, Brooke Army Medical Center and Madigan Army Medical Center) on key aspects of family health and functioning.