Effects of Probiotics on Streptococcus Mutans ve Lactobacillus Spp

Status Completed

Clinical Trial Summary

To evaluate the change of S. mutans and Lactobacillus spp. counts after all dental treatments were completed under general anesthesia and compare the groups in case of using probiotics and not using probiotics with the time for 6-months follow-up period.

Clinical Trial Description

Fifthy-eight pediatric patients without any systemical diseases whose dental treatments were completed under general anesthesia were included in the study. The study was carried out as two-groups; Group A: Patients who started using probiotics after general anesthesia and Group B: Patients who did not use probiotics after general anesthesia. The counts of S. mutans and Lactobacillus spp. were determined by quantitative polymerase chain reaction (qPCR) by analysis of saliva samples taken from all patients on the day before the general anesthesia (T0), at 1-month (T1), 3-month (T2) and 6-month (T3) follow-up periods. The statistical significance level was accepted as p<0.05. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05859646
Study type	Interventional
Source	Baskent University
Contact
Status	Completed
Phase	N/A
Start date	January 15, 2020
Completion date	May 15, 2022

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