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Stomach Neoplasms clinical trials

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NCT ID: NCT05071755 Not yet recruiting - Gastric Cancer Clinical Trials

Gastrectomy Outcomes in Elderly Patients

GOE
Start date: November 1, 2021
Phase:
Study type: Observational

In this study, the investigators aimed to identify independent prognostic factors for early postoperative complications and survival in elderly patients (aged ≥65 years) with gastric cancer.

NCT ID: NCT05070598 Recruiting - Clinical trials for HER2-positive Gastric Cancer

Camrelizumab Combined With Chemotherapy in First-line Treatment of HER2-positive Gastric Cancer

Start date: September 7, 2021
Phase: Phase 2
Study type: Interventional

According to the investigator's judgment, there are concomitant diseases that seriously endanger the patient's safety, or affect the patient's completion of the study (such as uncontrolled hypertension, diabetes, thyroid disease, etc.);

NCT ID: NCT05068635 Completed - Gastric Cancer Clinical Trials

Evaluation of the Efficacy of Distal Gastrectomy for the Treatment of Gastric Cancer (a Case Series)

Start date: January 1, 2013
Phase:
Study type: Observational

Case series of a retrospective study of patients operated for distal adenocarcinoma of the stomach, either by total gastrectomy or distal gastrectomy at Ibn Rochd University Hospital in Casablanca, with the analysis of outcome of patients on a follow up periode of three years and eight months.

NCT ID: NCT05068180 Recruiting - Prostatic Neoplasms Clinical Trials

Low-dose Neuroleptanalgesia for Postoperative Delirium in Elderly Patients

Start date: October 5, 2021
Phase: Phase 4
Study type: Interventional

Postoperative delirium(POD)is a common complication that can directly affect important clinical outcomes, and exert an enormous burden on patients, their families, hospitals, and public resources. In order to evaluate whether an intraoperative administration of low-dose neuroleptanalgesia reduces postoperative delirium, droperidol 1.25 mg and fentanyl 0.025 mg or normal saline is used by intravenous injection 30 minutes before the end of the operation, in elderly patients with non-cardiac major surgery under general anesthesia. The efficiency and safety of neuroleptanalgesia on the incidence of POD would be evaluated in elderly patients.

NCT ID: NCT05061082 Recruiting - Gastric Cancer Clinical Trials

Genomic Evolution of Metastasis in Gastric Cancer

Start date: October 26, 2021
Phase:
Study type: Observational

The aim of this study is to track tumor evolution of regional and distant metastases in gastric cancer using the Next Generation Sequencing technologies.

NCT ID: NCT05052931 Recruiting - Gastric Cancer Clinical Trials

Nab-paclitaxel Combined With Oxaliplatin and S-1 for Perioperative Treatment of Advanced Gastric Cancer

Start date: October 1, 2021
Phase: Phase 2
Study type: Interventional

This is a prospective, single-center, open, historically controlled real-world study. The aims of this study is to evaluate the safety and effectiveness of Nab-paclitaxel combined with oxaliplatin and S-1 in the treatment of patients with advanced gastric cancer.

NCT ID: NCT05052801 Recruiting - Gastric Cancer Clinical Trials

Bemarituzumab or Placebo Plus Chemotherapy in Gastric Cancers With Fibroblast Growth Factor Receptor 2b (FGFR2b) Overexpression

FORTITUDE-101
Start date: March 7, 2022
Phase: Phase 3
Study type: Interventional

The main objective of this study is to compare efficacy of bemarituzumab combined with oxaliplatin, leucovorin, and 5-fluorouracil (5-FU) (mFOLFOX6) to placebo plus mFOLFOX6 as assessed by overall survival (OS) in participants with FGFR2b ≥10% 2+/3+ tumor cell staining (FGFR2b ≥10% 2+/3+TC)

NCT ID: NCT05051670 Completed - Gastric Cancer Clinical Trials

da Vinci SP Robotic Gastrectomy

Start date: December 16, 2021
Phase: N/A
Study type: Interventional

Laparoscopic surgery revolutionized the surgical treatment of gastric cancer saving large incsion and associated pain. Robotic surgical system was introduced to enhance the minimally invasive surgery using articulating robotic arm. The da vinci SP system, which enables single-port surgery, can allow surgeon to provide radical gastrectomy with minimal scar and associated pain.

NCT ID: NCT05051423 Recruiting - Gastric Cancer Clinical Trials

"Mechanisms and Biomarkers of Response and Resistance to Current Targeted Therapies in Gastric Cancer" (THERRES)

THERRES
Start date: November 1, 2019
Phase:
Study type: Observational [Patient Registry]

The main aim was to assess the tumor vascular perfusion pattern in gastric cancer (GC). The investigators used dynamic contrast harmonic imaging endoscopic ultrasound (CHI-EUS) and the results were compared with the immunohistochemical expression of CD105 and clinico-pathological parameters.

NCT ID: NCT05043987 Withdrawn - Pancreatic Cancer Clinical Trials

Dose Escalation and Expansion Study of CPO102, an Anti-claudin 18.2 ADC in Patients With Advanced Cancers

Start date: November 16, 2022
Phase: Phase 1
Study type: Interventional

This Phase 1 study will be a multicenter, single agent, dose escalation and dose expansion study conducted in patients with advanced late stage cancer (pancreatic or gastric including esophageal junction cancers) for which the investigator determines there to be no other standard of care or higher priority therapies available.