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Stomach Neoplasms clinical trials

View clinical trials related to Stomach Neoplasms.

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NCT ID: NCT05111444 Not yet recruiting - Clinical trials for Gastroesophageal Junction Adenocarcinoma

Camrelizumab Plus Pyrotinib Plus Chemotherapy in Human Epidermal Growth Factor Receptor 2 Positive (HER2+) Advanced Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma

Start date: December 31, 2021
Phase: Phase 2
Study type: Interventional

This study is designed to evaluate the efficacy and safety of Camrelizumab plus pyrotinib in combination with chemotherapy in patients with HER2-positive gastric cancer.

NCT ID: NCT05101616 Suspended - Gastric Cancer Clinical Trials

A Pilot Study of Neoadjuvant Chemotherapy With or Without Camrelizumab for Locally Advanced Gastric Cancer

Start date: July 1, 2022
Phase: Phase 1/Phase 2
Study type: Interventional

It is a single-center, open-lable, randomized controlled trial to prospectively investigate the effectiveness and safety of Camrelizumab combined with DOS regimen chemotherapy in neoadjuvant treatment of patients with locally advanced gastric cancer.

NCT ID: NCT05095636 Recruiting - Gastric Cancer Clinical Trials

Apatinib Monotherapy Versus Apatinib Combined With Camrelizumab for Third-line Treatment of Metastatic Gastric Cancer

Start date: March 17, 2021
Phase: Phase 2
Study type: Interventional

This open, single-center, randomized phase II study was to evaluate the clinical benefit of apatinib plus camrelizumab which is an anti-Programmed cell death-1 (PD-1) monoclonal antibody, versus apatinib in patients with metastatic gastric cancer refractory to two or more lines of treatment, fully evaluating the efficacy and safety of the combined regimen.

NCT ID: NCT05095467 Not yet recruiting - Stomach Neoplasms Clinical Trials

HIPEC-AS in Patients With Peritoneal Metastasis of the Stomach or Esophagogastric Junction

Start date: October 2021
Phase: Phase 2
Study type: Interventional

HIPEC-AS01 is an open, prospective, single-center phase II clinical study, which will include "cT4aNxM0, P0 or cTxNxM1, P1" patients with gastric or esophagogastric junction adenocarcinoma, to evaluate the efficacy and safety of systemic chemotherapy with HIPEC combined with AS in the perioperative period. Patients enrolled will be divided into three groups. Among them, group A is the patients with locally resectable GC; group B is patients with peritoneal metastasis stage P1a or P1b, group C is patients with peritoneal metastasis stage P1c. The primary purpose is to evaluate the 3-year overall survival rate.

NCT ID: NCT05091528 Terminated - Clinical trials for HER2-positive Breast Cancer

A Safety and Activity Study of SBT6050 in Combination With Other HER2-directed Therapies for HER2-positive Cancers

Start date: February 8, 2022
Phase: Phase 1/Phase 2
Study type: Interventional

This study is designed to assess the safety and preliminary activity of SBT6050 in combination with trastuzumab deruxtecan (Part 1) or tucatinib plus trastuzumab +/- capecitabine (Part 2). Participants will be enrolled into each Arm based on cancer diagnosis and prior therapies.

NCT ID: NCT05088304 Completed - Malnutrition Clinical Trials

GLIM-defined Malnutrition Criteria for Postoperative Outcomes in Patients With Esophagogastric Cancer

Start date: September 1, 2015
Phase:
Study type: Observational

The present study aims to investigate the prognostic value of preoperative fat-free mass index for postoperative outcomes in patients undergoing esophagogastric cancer surgery, and to explore the role of the FFMI in the Global Leadership Initiative on Malnutrition (GLIM) criteria.

NCT ID: NCT05083338 Completed - Clinical trials for Malignant Solid Neoplasm

Psychological, Psychophysical and Epigenetic Determinants of Chronic Pain After Cytoreductive - Hyperthermic Intraoperative Chemotherapy

Start date: August 10, 2021
Phase:
Study type: Observational

This study learns if depression, anxiety, and catastrophizing (thought patterns that prompt people to expect the worst) are associated with chronic pain after surgery among patients who are scheduled to have cytoreductive surgery with intraoperative hyperthermic chemotherapy. Information from this study may improve the understanding of persistent and chronic postsurgical pain integrating multiple layers of biological and behavioral sciences.

NCT ID: NCT05076591 Recruiting - Clinical trials for Advanced Solid Tumor

IMM2902, a HER2/SIRPĪ± Bispecific mAb-Trap Antibody-receptor Fusion Protein, in Patients With HER2-expressing Advanced Solid Tumors

Start date: June 20, 2022
Phase: Phase 1
Study type: Interventional

This trial is a first-in-human, open label, multi-center, dose escalation phase 1a study followed by a disease-specific dose expansion phase 1b study to evaluate the safety, efficacy, and pharmacokinetics (PK) of IMM2902, a HER2/SIRPĪ± bispecific mAb-Trap antibody-receptor fusion protein, in patients with HER2-expressing advanced solid tumor.

NCT ID: NCT05076279 Recruiting - Gastric Cancer Clinical Trials

Safety and Efficacy of Single or Reduced Ports Laparoscopic Gastrectomy for Advanced Gastric Cancer (SPACE-01)

Start date: November 15, 2021
Phase: N/A
Study type: Interventional

The aim of this study is to verify the safety and efficacy of single or reduced ports laparoscopic gastrectomy for advanced gastric cancer.

NCT ID: NCT05075421 Completed - Gastric Cancer Clinical Trials

Prognostic Values of Inflammation-based Indices in Gastric Cancer

Start date: January 1, 2012
Phase:
Study type: Observational

This study aims to evaluate the prognostic values of preoperative inflammation-based indices in patients undergoing potentially curative resection of gastric cancer.