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Stomach Neoplasms clinical trials

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NCT ID: NCT05638048 Completed - Breast Cancer Clinical Trials

Effect of Precise Grip Strength Training on PICC Catheter-Related Thrombosis in Cancer Patients

Start date: July 10, 2022
Phase: N/A
Study type: Interventional

In this study, color Doppler ultrasound diagnostic instrument and electronic grip device were used to determine the best grip strength of patients with tumor PICC catheterization, formulate precise and standardized grip strength training guidance for them, provide personalized functional exercise health education, and observe the impact of precise grip strength training guidance on Peripheral central venous catheter-associated thrombosis. To provide a reference for clinical prevention of Peripheral central venous catheter-associated thrombosis in the future.

NCT ID: NCT05632939 Recruiting - Gastric Cancer Clinical Trials

ASKB589 in Combination With CAPOX and Sintilimab in Patients With Advanced, and Unresectable G/GEJ Cancer.

Start date: February 10, 2023
Phase: Phase 1/Phase 2
Study type: Interventional

This was an open-label, phase 1/2 study to evaluate safety, tolerability, pharmacokinetics, and antitumor activity of ASKB589 in combination with CAPOX and Sintilimab in first-line treatment of patients with locally advanced, recurrent, or metastatic gastric and esophagogastric junction adenocarcinoma.

NCT ID: NCT05631015 Active, not recruiting - Gastric Cancer Clinical Trials

Artificial Intelligence for Determination of Gastroscopy Surveillance Intervals

Start date: January 1, 2012
Phase:
Study type: Observational

The purpose of this study is to develop and validate a clinical decision support system based on automated algorithms. This system can use natural language processing to extract data from patients' endoscopic reports and pathological reports, identify patients' disease types and grades, and generate guidelines based follow-up or treatment recommendations

NCT ID: NCT05627414 Not yet recruiting - Gastric Cancer Clinical Trials

Conversion Therapy of Disitamab Vedotin Combined With Sintilimab and S-1 in HER2 Overexpression Gastric Cancer

Start date: January 1, 2023
Phase: Phase 2
Study type: Interventional

This is a phase II, one-arm study, which is aiming to evaluate the feasibility of combination of Disitamab Vedotin, Sintilimab and S-1 as conversion therapy in patients with HER2 overexpression unresectable gastric cancer .

NCT ID: NCT05625737 Not yet recruiting - Stomach Neoplasms Clinical Trials

Fruquintinib Combined With Sintilimab as Second-line Therapy for Gastric or Gastro-esophageal Junction Adenocarcinoma

Start date: November 2022
Phase: Phase 2
Study type: Interventional

This was a single-arm, prospective study to investigate the efficacy and safety of fruquintinib combined with sintilimab in the second-line treatment of Chinese patients with advanced gastric/GEJ adenocarcinoma.

NCT ID: NCT05620732 Recruiting - Clinical trials for Advanced Gastric Carcinoma

Treatment of Advanced Malignant Solid Tumors With Claudin18.2CAR-T

Start date: October 1, 2022
Phase: N/A
Study type: Interventional

The efficacy of advanced pancreatic cancer and gastric cancer needs to be further improved. Claudin is a kind of integrin membrane protein in the tight junction between epithelium and endothelium, which is highly expressed in gastric cancer and pancreatic cancer. Preclinical studies suggest that Claudin18.2CAR-T can effectively improve the remission rate of patients with advanced solid tumors.

NCT ID: NCT05620628 Recruiting - Clinical trials for Stomach Cancer, Adenocarcinoma

Ph2 Study of Savolitinib and Durvalumab (MEDI4736) Combination in Advanced MET Amplified Gastric Cancer(VIKTORY-2)

Start date: January 5, 2023
Phase: Phase 2
Study type: Interventional

For patients who failed primary chemotherapy with MET amplification, The efficacy and safety of the chemotherapy are evaluated by using dervalumab and saboritinib in combination.

NCT ID: NCT05619016 Recruiting - Breast Cancer Clinical Trials

[68Ga]Ga-ABY-025 PET for Quantification of HER2-status in Solid Tumors

Start date: November 23, 2022
Phase: Phase 2
Study type: Interventional

The goal of this phase II clinical trial is to improve the selection of patients with solid tumors who would benefit from effective treatment with HER2 targeted drugs. This will be achieved by examining patients with HER2 positive tumors in the esophagus or stomach or patients with advanced breast cancer with low HER2 expression (HER2low) with the HER2 specific positron emission tomography (PET) tracer ABY-025 (HER2-PET) and compare the imaging results with HER2 expression in tumor tissue derived from biopsies (reference standard).

NCT ID: NCT05618821 Recruiting - Gastric Cancer Clinical Trials

Clinical Outcomes of Indocyanine Green Tracer Using in Laparoscopic Gastrectomy With Lymph Node Dissection for Remnant Gastric Cancer

Start date: June 3, 2022
Phase: Phase 2
Study type: Interventional

Patients with resectable remnant gastric cancer were selected as study subjects to investigate the safety, efficacy, and feasibility of ICG near-infrared imaging tracing in guiding laparoscopic lymph node dissection for remnant gastric cancer by comparing injection ICG group and non-injection ICG group.

NCT ID: NCT05617469 Recruiting - Gastric Cancer Clinical Trials

DLCS for Predicting Neoadjuvant Chemotherapy Response

Start date: July 1, 2022
Phase:
Study type: Observational

The early noninvasive screening of patients suitable for neoadjuvant chemotherapy (NCT) is essential for personalized treatment in locally advanced gastric cancer (LAGC). The aim of this study was to develop and visualized a radio-clinical biomarker from pretreatment oversampled CT images to predict the response and prognosis to NCT in LAGC patients.