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Accelerated rTMS for Substance Use Disorder and Depression

Depression Clinical Trial

Official title:
Substance Use Disorder Treatment With Accelerated Repetitive Transcranial Magnetic Stimulation for Depression (START-D)

Clinical Trial Summary

This study is a small open-label feasibility trial of an accelerated course of repetitive transcranial magnetic stimulation (rTMS) for individuals with depression and stimulant use disorder [including methamphetamine or cocaine use disorder (MUD/CUD)].

Clinical Trial Description

This research is an open label feasibility trial of accelerated course of repetitive transcranial magnetic stimulation (rTMS) for individuals with stimulant use disorder. Participants will be recruited from an existing and ongoing longitudinal study of stimulant use disorder (STIM-RAD) (NCT06073340). Prior to initiating the accelerated course of rTMS, participants will undergo screening procedures to evaluate eligibility. Those eligible will complete up to four (4) rTMS sessions of intermittent theta burst over left dorsolateral prefrontal cortex per day, up to five (5) days per week of the study, for a total of 50 sessions over a three (3) week period and will undergo electroencephalography (EEG), electrocardiography (ECG), urine drug screens, as well as self-report and clinician-rated assessments. A follow-up visit will be conducted 1 week after the last session of rTMS. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06424184
Study type Interventional
Source University of Texas Southwestern Medical Center
Contact Taylor Helmbrecht, B.S.A.
Phone (214) 998-6504
Email Taylor.Helmbrecht@UTSouthwestern.edu
Status Not yet recruiting
Phase N/A
Start date June 2024
Completion date June 2027
View Details
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