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Stimulant Use clinical trials

View clinical trials related to Stimulant Use.

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NCT ID: NCT06424184 Not yet recruiting - Depression Clinical Trials

Accelerated rTMS for Substance Use Disorder and Depression

Start date: June 2024
Phase: N/A
Study type: Interventional

This study is a small open-label feasibility trial of an accelerated course of repetitive transcranial magnetic stimulation (rTMS) for individuals with depression and stimulant use disorder [including methamphetamine or cocaine use disorder (MUD/CUD)].

NCT ID: NCT06073340 Recruiting - Healthy Clinical Trials

The Longitudinal Study of Stimulant Use Disorder

STIM-RAD
Start date: November 16, 2023
Phase:
Study type: Observational

This research is a 5-year observational, longitudinal registry study with no treatment or medication provided as part of participation. Individuals with current or lifetime stimulant use disorder, in addition to healthy control individuals, may be eligible to participate in this study. A variety of assessments and tasks including Magnetic Resonance Imaging (MRI), Electroencephalography (EEG), blood draws, urine drug screens, and both self-report and clinician-rated assessments will be used to assess biomarkers in this population. This study has a visit schedule of four in-person visits and eight remote visits per year.

NCT ID: NCT05835921 Recruiting - Clinical trials for Substance Use Disorders

Enhancing Prospective Thinking in Early Recovery

RENTS
Start date: March 28, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to use a novel virtual reality intervention to test for efficacy in reducing stimulant use and increasing abstinence, with concomitant increases in future self-identification, future time perspective, and delay-of-reward, in early recovering stimulant use disorder (StUD) persons. The main question[s] this trial aims to answer are: - Will the Virtual Reality (VR) intervention decrease the number of stimulant use days? - Will the VR intervention produce longer abstinence periods during follow-up visits? - Will the VR intervention increase stimulant drug abstinence rates? - Will the VR intervention increase future self-identification? - Will the VR intervention increase self-reported future time perspective? - Will the VR intervention increase preference for delayed rewards in a laboratory delay discounting task on the study day? - Will the VR intervention produce gains in the behavioral effects of future self-identification, future time perspective, and delayed rewards at the 30-day and 6-month follow-ups? Researchers will compare the experimental and control groups to see if there are differences in the results for the questions outlined above.

NCT ID: NCT05787847 Recruiting - Stimulant Use Clinical Trials

Financial Incentives to Promote Stimulant Abstinence in a Community-Based Syringe Exchange Program

Start date: February 14, 2024
Phase: N/A
Study type: Interventional

The goal of this randomized control pilot study is to learn about a financial incentives intervention among individuals who use stimulants and take part in a community-based syringe exchange program. The main question it aims to answer is how financial incentives for not using stimulants will impact stimulant use. Participants in the experimental group will have the opportunity to earn financial incentives for providing a negative urine sample for stimulants using a point-of-care test, which indicates abstinence from stimulant use, along with health education on the health risks of stimulant use and substance injection. Researchers will compare the experimental group to the control group who will receive health education on the health risks of stimulants use and injection.

NCT ID: NCT05379959 Completed - Motivation Clinical Trials

Effects of Stimulants on Behavioral and Neural Markers of Social Motivation, Ability, and Neural Markers of Social Function

MASM
Start date: May 11, 2022
Phase: Early Phase 1
Study type: Interventional

To study the effects of MDMA, compared to a prototypical stimulant, on social motivation, social ability, and neural indices of social function in healthy volunteers

NCT ID: NCT05140876 Recruiting - HIV-1-infection Clinical Trials

Supporting Treatment Adherence for Resilience and Thriving (START)

START
Start date: June 15, 2022
Phase: N/A
Study type: Interventional

This Phase II randomized controlled trial is testing the efficacy of a cell phone application called START for helping men who use stimulants like methamphetamine to get the most out of their HIV treatment.

NCT ID: NCT05097547 Not yet recruiting - Clinical trials for Contingency Management

Contingency Management for Stimulant Use Disorders

Start date: October 2021
Phase: N/A
Study type: Interventional

The invetigators' objective is to implement Medication Assisted Treatment (MAT) and contingency management in patients affected by co-occurring opioid use disorder and stimulant use disorder. Participants will continue to receive standard of care for their opioid use disorder via MAT at our Outpatient Based Opioid Treatment (OBOT) Clinic. Participants' stimulant use disorder will be targeted through contingency management, with twice weekly urine drug screens and monetary prizes in exchange for negative urine drug screens. Through regular clinic visits and the use of incentives, the investigators hope to increase treatment adherence and increase the number of negative urine drug screens in subjects struggling with co-morbid opioid use disorder and stimulant use disorder. The investigators will determine whether or not this treatment is effective in this population, versus conventional treatment (baseline therapy patients were getting through OBOT). The investigators' primary outcome measure will be stimulant abstinence duration during the twelve week study.

NCT ID: NCT04907357 Active, not recruiting - Cocaine Dependence Clinical Trials

rTMS for Stimulant Use Disorders

CTN-0108
Start date: February 4, 2022
Phase: N/A
Study type: Interventional

The purpose of the study is to determine feasibility of repetitive transcranial magnetic stimulation (rTMS) for individuals with moderate to severe cocaine or methamphetamine use disorder (CUD/MUD). Potential participants will be age 18-65, and interested in cutting down or stopping use. Participants will be randomized to one of two groups; groups will receive rTMS or sham rTMS (placebo) over the course of an 8-week treatment period, and complete follow-up assessments at the end of treatment, 12, and 16 weeks post-randomization.

NCT ID: NCT04899024 Recruiting - Clinical trials for Medication Adherence

PrEP Affect Regulation Treatment Innovation

PARTI
Start date: January 31, 2022
Phase: N/A
Study type: Interventional

This multi-site randomized controlled trial enrolling sexual minority men who use stimulants and are currently taking pre-exposure prophylaxis (PrEP). This randomized controlled trial will test the efficacy of a PrEP Affect Regulation Treatment Innovation (PARTI) condition comprised of a 5-session positive affect intervention delivered during smartphone-based Contingency Management (CM) for directly observed PrEP doses (PARTI+CM) compared to an attention-control condition delivered during CM. The primary outcome is HIV acquisition risk measured using a combination of tenofovir-diphosphate levels in dried blood spots that are indicative of sub-optimal adherence to PrEP and recent condomless anal sex.

NCT ID: NCT04642820 Recruiting - Stimulant Use Clinical Trials

Drugs Brain and Behavior (DDP)

DDP
Start date: November 1, 2020
Phase: Early Phase 1
Study type: Interventional

In this project, we will examine individual differences in the effects of a stimulant drug, methamphetamine (MA), on mesolimbic reward function using fMRI.