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Stenosis clinical trials

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NCT ID: NCT02485574 Completed - Stenosis Clinical Trials

Anterior Bridging Cage With Bone Substitute Versus Localized Autobone in Transforaminal Lumbar Interbody Arthrodesis

Start date: March 2015
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluation for the pattern of bone bridging of patients who undergo transforaminal lumbar interbody arthrodesis, the investigators hypothesize that auto local bone mixed with β-calcium phosphate + hydroxyapatite (OSTEON 2, Genoss) is not inferior to auto local bone only. In addition, the investigators will analyze anterior new bone bridging pattern between anterior bridging cage newly developed and grafted bone in anterior disc space.

NCT ID: NCT02475291 Completed - Clinical trials for Coronary Artery Disease

Clinical Usefulness of Fractional Flow Reserve Measurement for Significant Stenosis in Proximal Coronary Artery

Start date: June 2015
Phase: N/A
Study type: Observational

Fractional flow reserve (FFR) is a pressure-wire-based index that is used during coronary angiography to assess the potential of a coronary stenosis to induce myocardial ischemia. Recent ESC guidelines referred to the usefulness of FFR extensively when noninvasive stress imaging is contraindicated, non-diagnostic, or unavailable. However, FFR requires additional manipulation with maximal and stable hyperemia by intravenous adenosine. More routine use of FFR for all angiographically significant stenoses would add considerable time, cost, and complexity to each PCI procedure and might also increase the risk of catheter-related complications such as coronary dissection and perforation. Although the guideline mentioned that FFR may not be useful in very high grade lesions (angiographically >90%) which always have an FFR <0.80, it have not been revealed yet proper criteria to predict FFR <0.80 obtained by angiographic parameters including degree of stenosis, lesion location and vessel size. It would be valuable to find more precise criteria available by conventional angiography for discrimination of functional stenosis in way to reduce the risk of additional procedure. For the purpose, the investigators will perform FFR in the lesions with significant stenosis (>70% diameter stenosis by visual estimation) and compare the angiographic parameters and FFR values in the study.

NCT ID: NCT02428582 Active, not recruiting - Arteriosclerosis Clinical Trials

Covered Stents Versus Bare-Metal Stents

Start date: May 2016
Phase: N/A
Study type: Interventional

To compare the outcome of revascularisation the gastrointestinal arteries using covered stents compared to bare-metal stents in patients with CGI.

NCT ID: NCT02395354 Recruiting - Crohn's Disease Clinical Trials

Comparative Prospective Multicenter Randomized Study of Endoscopic Treatment of Stenosis in Crohn´s Disease

PROTDILAT
Start date: September 2013
Phase: N/A
Study type: Interventional

This study will be a multicentre randomized controlled trial to assess the efficacy between balloon dilatation and self-expanding metallic stent placement for endoscopic treatment of stenosis in Crohn´s Disease.

NCT ID: NCT02373852 Completed - Stenosis Clinical Trials

PMS Retrospective Study of WIRION Performance in Patients Undergoing Saphenous Vein Graft (SVG) Intervention

Start date: October 2014
Phase:
Study type: Observational

The objective of this study is to collect data on the use of the WIRION system in Patients undergoing Percutaneous Intervention of Saphenous Vein Graft (SVG).

NCT ID: NCT02317185 Terminated - Clinical trials for Degenerative Disc Disease

Clinical Evaluation of GENEX® DS in Instrumented Posterolateral Fusion

Start date: December 2014
Phase:
Study type: Observational

The overall goal of this clinical study is to characterize the fusion rate of geneX® ds bone graft substitute in comparison to autograft, which is considered the gold standard for posterolateral fusion. Assessments are made using AP and Lateral x-rays, F/E x-rays, and CT scans geneX® ds has been cleared by the FDA for use in these procedures; however this study will allow more detailed characterization of geneX® ds performance in the long-term (1 year). By using the patient as their own control, direct comparison to autograft can be performed while minimizing other variables.

NCT ID: NCT02266238 Not yet recruiting - Clinical trials for Arteriovenous Fistula

Stenosis of Arteria-Venous Fistula in Maintenance Hemodialysis Patients: Early Intervention Trial

SAVEIT
Start date: January 2015
Phase: N/A
Study type: Interventional

The purpose of this study is to compare the effect of DSA guided percutaneous balloon dilatation, ultrasound guided percutaneous balloon dilatation and surgical repair in the treatment of Stenosis of Arteria-Venous Fistula in Maintenance Hemodialysis Patients.

NCT ID: NCT02049463 Not yet recruiting - Stroke Clinical Trials

Advanced Analysis of the Carotid Phonoangiography and Diseases

Start date: February 2014
Phase: N/A
Study type: Observational

Purpose: To investigate the different sound spectrum of carotid arteries and to analyze its relationship to the vessel disease, and to build a new biomarker about vascular disorder. Methods: To record the carotid phonoangiography with digital stereoscopy and analysis the spectrum with different algorithm such as FFT, wavelet, entropy, complexity, and HHT. The results will be correlated and comparison to the finding in clinical, carotid Doppler and duplex, CTA, MR, and catheter angiography. Statistics: The significance of difference between parameters was computed using t-tests or paired t-test etc. A p value <0.05 is defined as significant.

NCT ID: NCT02018445 Completed - Stenosis Clinical Trials

Accell Evo3™ Demineralized Bone Matrix in Instrumented Lumbar Spine Fusion

Start date: November 2013
Phase: N/A
Study type: Interventional

The objective of this study is to prospectively evaluate the performance of Integra Accell Evo3 Demineralized Bone Matrix as an adjunct for instrumented posterolateral spine fusion, as compared to local autograft.

NCT ID: NCT01970579 Completed - Stenosis Clinical Trials

Clinical Trial on Peripheral Arteries Treated With SeQuent® Please P Paclitaxel Coated Balloon Catheter

ConSeQuent
Start date: October 2013
Phase: Phase 3
Study type: Interventional

The aim of the study is to assess the safety and efficacy of the paclitaxelreleasing balloon catheter SeQuent® Please P to treat de novo and restenotic lesions in the superficial femoral artery and the proximal two segments of the popliteal artery with reference diameters ≥ 4mm & ≤ 7mm and lesion lengths ≥ 4 cm & ≤ 27 cm. It is the intention of this trial to treat suitable target lesions with DCB only.