Clinical Trials Logo

Starvation clinical trials

View clinical trials related to Starvation.

Filter by:

NCT ID: NCT06186245 Enrolling by invitation - Diabetes Mellitus Clinical Trials

Starvation in the Treatment of Diabetic Ketoacidosis

Start date: December 27, 2023
Phase: N/A
Study type: Interventional

Diabetic ketoacidosis (DKA) and hyperosmolar hyperglycemic state (HHS) are common, but serious metabolic disorders are often encountered in intensive care. In the intensive care setting, it is common to withhold food from patients during treatment of DKA. However, there is no evidence or current literature supporting this practice. The following proposed research investigates the initiation of an early diet versus withholding food during the treatment of diabetic ketoacidosis.

NCT ID: NCT05967858 Completed - Starvation Clinical Trials

Incidence of Refeeding Syndrome in Consecutively Admitted Patients

Start date: December 1, 2013
Phase:
Study type: Observational

The incidence and main risk-factors analyzed in consecutive in-patients in the departments og gastroenterology and ear-nose and throat diseases (cancer in radiation therapy)

NCT ID: NCT05919992 Recruiting - Clinical trials for Glucocorticoid Effect

The Role of Glucocorticoids to Maintain Energy Homeostasis During Starvation (Gluco-Starve)

Start date: May 15, 2023
Phase: Early Phase 1
Study type: Interventional

In a randomized, cross-over study, 20 healthy volunteers will receive a block and replace therapy that mimics physiological GC rhythm (metyrapone plus hydrocortisone) or placebo. Participants will undergo two identical fasting periods with each treatment. With the block and replace therapy, fasting-induced GC peak will be suppressed. Metabolic and autonomic parameters will be compared to reveal whether GCs mediate the physiological adaptions to caloric restriction. Understanding acute effects of GCs upon caloric restriction is critical, since repetitive disruptions of GC secretion may become harmful in chronic conditions.

NCT ID: NCT04060433 Recruiting - Anorexia Nervosa Clinical Trials

Implementation of Evidence-Based Treatment of Restrictive Eating Disorder With Pronounced Starvation

ROCKETLAUNCH
Start date: October 1, 2020
Phase: N/A
Study type: Interventional

In the Region Skåne in Sweden, the investigators have developed guidelines for providing intensive and evidence-based treatment during the first month in case of severe restrictive eating disorder with pronounced starvation. The project is aiming at implementing this treatment program in the general Child Psychiatric clinic, with its main focus on the implementation of evidence based family therapy. The study aims to evaluate the implementation of a standardized treatment model during the first month. The outcome will be compared with the patients and families who have been in treatment before the ROCKETLAUNCH project started.

NCT ID: NCT03600311 Completed - Weight Loss Clinical Trials

Resistance Exercise and Protein During Weight Loss

RIDE
Start date: August 31, 2018
Phase: N/A
Study type: Interventional

The purpose of this study is to determine if post-exercise protein supplementation can rescue the anabolic response of muscle and bone to resistance exercise during caloric restriction.

NCT ID: NCT03573063 Completed - PCOS Disease Clinical Trials

Studying the Starvation Effect on Androgen Metabolism in 20 Healthy Young Women and Comparison to Women With PCOS.

SEA
Start date: October 26, 2018
Phase: N/A
Study type: Interventional

In this study, the investigators wanted to investigate the energy homeostasis and the steroid metabolism of 20 healthy, young and normal weight women aged between 16-35 years before and after a 48 hours fasting period. The following substrates and hormone concentrations representing the carbohydrate, fat and protein metabolism will be measured from plasma or urine before and after fasting: glucose, insulin, lactate, alpha-synucleine, free fatty acids, beta-hydroxybutyrate (ketone bodies), carnitine (surrogate for acetyl-CoA) and alanine (amino acids). In addition, the investigators will measure 67 steroid metabolites by GC/MS and Biokrates AbsolutIDQ Steroid Assay in all collected urines and blood samples. In the analysis of the data, the investigators will focus on correlations between biochemical parameters of the energy metabolism and parameters of the steroid metabolism, specifically the androgens. In addition, the steroid profiles obtained from healthy young women before and after fasting will be compared to steroid profiles of PCOS women in search for specific differences.

NCT ID: NCT03220997 Not yet recruiting - Caesarean Section Clinical Trials

Do Preoperative Carbohydrate Drinks Prevent Preoperative Catabolism in Mothers Undergoing Elective Caesarean Section? A Randomised Controlled Study

Start date: August 2017
Phase: N/A
Study type: Interventional

The primary aim of this randomised control trial is to assess the impact of pre-operative carbohydrate loading on the incidence of urinary ketone bodies when compared to standard care in elective caesarean section. Half of the participants will receive pre-operative carbohydrates and the other half will receive standard care.

NCT ID: NCT02945410 Completed - Weight Loss Clinical Trials

Effect of Caloric Restriction and Protein Intake on Metabolism and Anabolic Sensitivity

Start date: September 2016
Phase: N/A
Study type: Interventional

The purpose of this study is to determine if an increased protein intake can attenuate the suppression of metabolic and anabolic hormones during caloric restriction

NCT ID: NCT02607826 Not yet recruiting - Colorectal Cancer Clinical Trials

Short-term Starvation vs. Normal Diet Before Chemotherapy of Solid Tumors

Start date: November 2016
Phase: N/A
Study type: Interventional

Recent pre-clinical data provide strong evidence that short-term starvation before the administration of cytostatic drugs for the chemotherapy of solid tumors leads to significantly higher efficacy and lower toxicity levels. However, these findings have so far not been validated in patients. The aim of this trial is to provide first clinical evidence regarding the impact of pre-chemotherapeutic short-term starvation on response to therapy (primary endpoint). Additionally, progression-free survival, adverse events, and overall survival will be monitored (secondary endpoints). In perspective, short-term starvation before chemotherapy could represent a simple and secure way to improve both efficacy and tolerance of chemotherapies at low cost.

NCT ID: NCT02364661 Not yet recruiting - Infection Clinical Trials

The Influence of Short-term Starvation on Hepatitis B Virus Load

Start date: March 2015
Phase: N/A
Study type: Interventional

Hepatitis B virus is a small DNA virus that affects 400 million people worldwide. The virus infects the liver and previous studies, done in tissue culture and in animals, have shown that viral replication is affected by metabolic changes occurring in the liver. Specifically, starvation induces HBV gene expression and replication, in parallel to the activation of the gluconeogenesis response, and feeding attenuates viral activity. In this study we are going to recruit HBV patients with detectable viremia and analyze their viral load after an over night starvation versus after a morning meal. Our hypothesis is that following an over-night starvation viral load will be higher than that in the fed state.