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Stage I Prostate Cancer AJCC v8 clinical trials

View clinical trials related to Stage I Prostate Cancer AJCC v8.

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NCT ID: NCT04519879 Recruiting - Clinical trials for Prostate Adenocarcinoma

White Button Mushroom Sup for the Reduction of PSA in Pts With Biochemically Rec or Therapy Naive Fav Risk Prostate CA

Start date: May 10, 2021
Phase: Phase 2
Study type: Interventional

This phase II trial studies how well white button mushroom supplement works in reducing prostate-specific antigen (PSA) levels in patients with prostate cancer that has come back (recurrent) or has favorable risk and has not undergone any therapy (therapy naive). PSA is a blood marker of prostate growth. White button mushroom supplement may affect PSA level, various parameters of immune system and levels of hormones that may have a role in prostate cancer growth.

NCT ID: NCT04253483 Recruiting - Clinical trials for Stage II Prostate Cancer AJCC v8

Comparison of High-Dose Rate Brachytherapy and Stereotactic Ablative Radiotherapy as Monotherapy for the Treatment of Localized Prostate Cancer

Start date: July 17, 2019
Phase: Phase 2
Study type: Interventional

This phase II trial compares high-dose rate brachytherapy and stereotactic ablative radiotherapy as monotherapy in treating patients with prostate cancer that has not spread to other parts of the body (localized). High-dose rate brachytherapy delivers radiation directly into the prostate within a few minutes by a single radioactive seed through temporarily placed plastic catheters inside the prostate gland. Stereotactic ablative radiotherapy is an external beam radiation method that delivers large doses of radiation to the cancer in a short period of time, usually 5 treatments. This trial aims to find which of these two approaches is better in terms of patient-reported quality of life.

NCT ID: NCT04189770 Recruiting - Cancer Survivor Clinical Trials

Lifestyle Behavior Influences Among African American Patients With Stage 0-III Prostate Cancer Survivors and Their Partners

Start date: February 26, 2020
Phase:
Study type: Observational

This trial studies the day-to-day stress, social support, and health lifestyle behaviors (such as physical activity and nutrition) in African American patients with stage 0-III prostate cancer survivors and their partners. How patients cope with stress may affect their lifestyle behaviors. This study may help understand not only survivors' behaviors but also partners' behaviors and how they interact.

NCT ID: NCT04134260 Recruiting - Clinical trials for Prostate Adenocarcinoma

Testing the Addition of the Drug Apalutamide to the Usual Hormone Therapy and Radiation Therapy After Surgery for Prostate Cancer

Start date: March 5, 2020
Phase: Phase 3
Study type: Interventional

This phase III trial studies whether adding apalutamide to the usual treatment improves outcome in patients with lymph node positive prostate cancer after surgery. Radiation therapy uses high energy x-ray to kill tumor cells and shrink tumors. Androgens, or male sex hormones, can cause the growth of prostate cancer cells. Drugs, such as apalutamide, may help stop or reduce the growth of prostate cancer cell growth by blocking the attachment of androgen to its receptors on cancer cells, a mechanism similar to stopping the entrance of a key into its lock. Adding apalutamide to the usual hormone therapy and radiation therapy after surgery may stabilize prostate cancer and prevent it from spreading and extend time without disease spreading compared to the usual approach.

NCT ID: NCT03987386 Recruiting - Clinical trials for Stage IVA Prostate Cancer AJCC v8

Conventional or Hypofractionated Radiation Therapy in Treating Patients With Prostate Cancer

Start date: May 30, 2019
Phase: Phase 3
Study type: Interventional

This phase III trial studies how well hypofractionated radiation therapy works compared to the conventional one in treating patients with prostate cancer. Radiation therapy uses high energy beams to kill tumor cells and shrink tumors. Hypofractionated radiation therapy delivers higher doses of radiation therapy over a shorter period of time and may kill more tumor cells and have fewer side effects.

NCT ID: NCT02600156 Recruiting - Prostate Cancer Clinical Trials

Focal Laser Ablation of Low to Intermediate Prostate Cancer Tumors

Start date: September 1, 2015
Phase: N/A
Study type: Interventional

The primary purpose of this study is to evaluate the feasibility and safety of MRI-guided focal laser ablation (Laser-Induced Interstitial Thermal Therapy, LITT) to treat low-risk native prostate cancer.