Squamous Cell Carcinoma of Head and Neck Clinical Trial
Official title:
Phase II Trial of Magrolimab and Cetuximab With Pembrolizumab or Docetaxel for Recurrent/Metastatic Head Neck Squamous Cell Carcinoma
To learn if magrolimab, along with a combination of commercially-available drugs (cetuximab, pembrolizumab, and docetaxel) can help to control HNSCC in combination with other drugs. The safety of magrolimab will also be studied.
Primary Objectives: -Objective response rate (ORR) per RECIST v1.1 Secondary Objectives: - Adverse events rates per CTCAE V5.0 (appendix) - Duration of response (DOR) - Progression free survival (PFS) per RECIST v1.1 - Overall survival (OS) per RECIST v1.1 Exploratory Objectives: -Assessment of blood and tissue-based biomarkers predictive of response to therapy ;
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