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Spinal Fusion clinical trials

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NCT ID: NCT06368245 Not yet recruiting - Spinal Fusion Clinical Trials

Durability of Suppl. Rod Constructs-SuppleMentAry Rod Technique for Long-segment Posterior Instrumented Spinal Fusions

Start date: October 15, 2024
Phase:
Study type: Observational

This is a multicenter retrospective comparative cohort study. The index surgery for this study is primary or revision long-segment posterior thoracolumbar (TL) instrumented fusion using either a supplementary rod construct or a dual-rod construct. Eligible patients who already had index surgery, will be identified for enrollment through a review of medical records of the participating surgeons at the study sites.

NCT ID: NCT06357234 Not yet recruiting - Anesthesia Clinical Trials

Aprepitant Treatment to Prevent Postoperative Nausea and Vomiting in Children Undergoing Scoliosis Surgery

Start date: June 2024
Phase: Phase 2
Study type: Interventional

This research trial will measure how useful Aprepitant is in preventing nausea and vomiting in children having surgery to correct scoliosis (curvature of the spine).

NCT ID: NCT06067893 Not yet recruiting - Clinical trials for Adolescent Idiopathic Scoliosis

Low Dose Dexmedetomidine as a Postoperative Pain Adjunct

Start date: July 2024
Phase: Phase 4
Study type: Interventional

This randomized controlled trial examines whether the addition of a low-dose dexmedetomidine infusion to our current multimodal pain management plan decreases narcotic consumption and reduces side effects in adolescent patients undergoing posterior spinal fusion for idiopathic scoliosis.

NCT ID: NCT06020417 Not yet recruiting - Spinal Fusion Clinical Trials

Pedicle Screw Malposition in Spine Arthrodesis Surgeries With O-ARM-guided Navigation

NoHARM
Start date: August 1, 2024
Phase: N/A
Study type: Interventional

Background: Throughout the history of spinal deformity there have been continuous advances in the surgical treatment. Although many techniques have been successfully developed despite the anatomy complex, screw placement still remains difficult with a significant risk of misplaced implants. The O-ARM guided Navigation is a scanner that allows imaging of screws intraoperatively and could be a tool to facilitate screw revision and reduce the occurrence of misplaced implants. Methods: This is a prospective and randomized clinical study that will be carried out at the University Hospital of the Federal University of Piaui, which provides exclusive assistance to patients of the Unified Health System (UHS), in northeastern Brazil.

NCT ID: NCT06003010 Not yet recruiting - Clinical trials for Adolescent Idiopathic Scoliosis

Yoga for Adolescent Idiopathic Scoliosis (AIS) Patients

Start date: September 2023
Phase: N/A
Study type: Interventional

Adolescent Idiopathic Scoliosis (AIS) is defined as a three-dimensional lateral deformity of the spine. It is described with a cobb angle of greater than 10 degrees. There is no known etiology of AIS. Once the degrees of curvature become severe (greater than 45 degrees), surgical intervention (posterior spinal fusion - PSF) is often discussed. Most adolescent patients and their families opt for surgical correction to decrease future complications of severe scoliosis, such as decreased vital capacity of the lungs, potential future activity restrictions, cosmetic appearance, and self-esteem. While the patient and family are eager to undergo PSF, they do have concerns. The major concerns are pain control and their ability to return to activities. In current literature, there are many studies completed regarding pharmacologic pain control management with the use of IV patient-controlled analgesia (PCA) with opioids, narcotics, non-steroidal anti-inflammatories, muscle relaxers, Tylenol, and gabapentin. However, there is not a well-established multimodal pain management plan for postoperative PSF patients. There is also no current literature discussing nonpharmacologic pain management methods, such as stretching, strengthening and yoga, for patients undergoing PSF. There are multiple studies discussing core stabilization used for helping AIS patients non-operatively. There is no literature discussing the use of nonpharmacologic pain management methods for improved pain control (including decreased use of pharmacologic agents) and quicker return to activities. The aim of this study is to determine if patients with AIS undergoing PSF require fewer pain medications and have an earlier return to activities if completing a yoga program six weeks prior to their surgery.

NCT ID: NCT05911477 Not yet recruiting - Osteoporosis Clinical Trials

Recombinant Human Bone Morphogenetic Protein-2(rhBMP-2) in Patients With Osteoporosis After Lumbar Fusion

Start date: July 1, 2023
Phase: N/A
Study type: Interventional

rhBMP-2 has been used to promote spinal fusion. Despite potential risk of complications, satisfied results could be obtained with low dose of rhBMP-2. Effect of early bone formation has been validated using rat ovariectomy osteoporosis model. However, whether it functioned in patients with osteoporosis remained unknown. In this study, the investigators intend to investigate whether rhBMP-2 promotes early bone formation in patients with osteoporosis after transforaminal lumbar interbody fusion (TLIF).

NCT ID: NCT05755334 Not yet recruiting - Pain Clinical Trials

Ropivacaine Pharmacokinetics After Erector Spinae Block

PK
Start date: June 1, 2023
Phase: Phase 4
Study type: Interventional

The primary aim is to evaluate the analgesic efficacy of either technique by measuring cumulative morphine consumption in the first 24 hours after an erector spinae plane block with 2 ml/kg of ropivacaine 0.1% (2 ml/kg) or 1 ml/kg of ropivacaine 0.2%. The secondary aim of this study is to describe the pharmacokinetics of ropivacaine 0.1% and ropivacaine 0.2% after erector spinae block in children undergoing posterior spinal fusion.

NCT ID: NCT03692845 Not yet recruiting - Spinal Fusion Clinical Trials

Minimally Invasive Versus Open Transforaminal Lumbar Interbody Fusion

Start date: November 2018
Phase: N/A
Study type: Interventional

A study that compares between Open TLIF and Minimally invasive TLIF regarding patients' functional status(Oswestry Disability index)as a primary outcome measure.