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Spinal Fusion clinical trials

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NCT ID: NCT06368245 Not yet recruiting - Spinal Fusion Clinical Trials

Durability of Suppl. Rod Constructs-SuppleMentAry Rod Technique for Long-segment Posterior Instrumented Spinal Fusions

Start date: October 15, 2024
Phase:
Study type: Observational

This is a multicenter retrospective comparative cohort study. The index surgery for this study is primary or revision long-segment posterior thoracolumbar (TL) instrumented fusion using either a supplementary rod construct or a dual-rod construct. Eligible patients who already had index surgery, will be identified for enrollment through a review of medical records of the participating surgeons at the study sites.

NCT ID: NCT06357234 Not yet recruiting - Anesthesia Clinical Trials

Aprepitant Treatment to Prevent Postoperative Nausea and Vomiting in Children Undergoing Scoliosis Surgery

Start date: June 2024
Phase: Phase 2
Study type: Interventional

This research trial will measure how useful Aprepitant is in preventing nausea and vomiting in children having surgery to correct scoliosis (curvature of the spine).

NCT ID: NCT06282770 Recruiting - Spinal Fusion Clinical Trials

Photobiomodulation for Lower Back Pain Post Spinal Fusion and Decompression Surgery

Start date: July 1, 2023
Phase: N/A
Study type: Interventional

After spinal fusion and decompression surgery there is a possible risk of developing chronic back pain. After surgery there is typically inflammation around the operation site and this inflammation can be painful and debilitating to patients. Many possible treatment plans have been incorporated to assist the patient with recovery - notably medications, physical therapy, and braces. However, few studies have looked at laser diodes that utilize high-power laser lights that are aimed at decreasing pain and inflammation. Investigators aim to look compare patients using a back brace with laser diodes within versus those who wear a normal brace used as a placebo. Investigators will also assess the patient's surgical wound to monitor the progression of wound healing while using the brace.

NCT ID: NCT06233617 Recruiting - Spinal Stenosis Clinical Trials

Dexamethasone vs. Dexmedetomidine for ESPB in Pain Management After Spine Surgery

Start date: March 1, 2024
Phase: Phase 4
Study type: Interventional

Effect of perineurial dexamethasone and dexmedetomidine on erector spinal plane block duration for spine surgery.

NCT ID: NCT06120231 Recruiting - Spinal Stenosis Clinical Trials

Pulse-Width Modulation

Start date: December 1, 2023
Phase: N/A
Study type: Interventional

The overarching aim of this project is to modulate the pulse-width during stimulation of pedicle screws and record the response thresholds associated with each PWM setting. During this initial phase of the investigation, no further data will be collected.

NCT ID: NCT06119542 Recruiting - Spinal Fusion Clinical Trials

Endothelial Damage in Major Spine Surgery, Measured by Circulating Syndecan-1: an Observational Study.(GlycOrtho)

GlycOrtho
Start date: February 28, 2022
Phase:
Study type: Observational

The goal of this observational study is to learn about endothelial damage in major spine surgery, expressed as rise in circulating Syndecan-1. The main questions it aims to answer are: - What is the extent of endothelial glycocalyx shedding in major spine surgery? - Are there differences in different type of surgical populations? (adolescent idiopathic scoliosis, adult degenerative spine disease, oncologic surgery) To do so, blood samples will be drawn from participants at the following timepoints: - basal - after surgery - if transfusion of Fresh Frozen Plasma: before and after transfusion - Post-Operative Day 1-2-4

NCT ID: NCT06067893 Not yet recruiting - Clinical trials for Adolescent Idiopathic Scoliosis

Low Dose Dexmedetomidine as a Postoperative Pain Adjunct

Start date: July 2024
Phase: Phase 4
Study type: Interventional

This randomized controlled trial examines whether the addition of a low-dose dexmedetomidine infusion to our current multimodal pain management plan decreases narcotic consumption and reduces side effects in adolescent patients undergoing posterior spinal fusion for idiopathic scoliosis.

NCT ID: NCT06042699 Recruiting - Anemia Clinical Trials

Scoliosis Iron Supplementation Study

Start date: January 11, 2024
Phase: N/A
Study type: Interventional

This study is a randomized controlled trial of preoperative oral iron supplementation, to identify whether iron deficiency is a modifiable risk factor for adverse surgical outcomes such as red blood cell transfusion and diminished postoperative cognitive and physical capacity in adolescents undergoing scoliosis surgery. Research Question(s)/Hypothesis(es): Primary - Iron supplementation will reduce the incidence of perioperative RBC transfusion in iron deficient scoliosis patients undergoing spinal fusion. Secondary - Iron supplementation will reduce postoperative neurocognitive functional declines in iron deficient scoliosis patients undergoing spinal fusion. - Iron supplementation will improve patient-reported physical functioning in iron deficient scoliosis patients undergoing spinal fusion.

NCT ID: NCT06020417 Not yet recruiting - Spinal Fusion Clinical Trials

Pedicle Screw Malposition in Spine Arthrodesis Surgeries With O-ARM-guided Navigation

NoHARM
Start date: August 1, 2024
Phase: N/A
Study type: Interventional

Background: Throughout the history of spinal deformity there have been continuous advances in the surgical treatment. Although many techniques have been successfully developed despite the anatomy complex, screw placement still remains difficult with a significant risk of misplaced implants. The O-ARM guided Navigation is a scanner that allows imaging of screws intraoperatively and could be a tool to facilitate screw revision and reduce the occurrence of misplaced implants. Methods: This is a prospective and randomized clinical study that will be carried out at the University Hospital of the Federal University of Piaui, which provides exclusive assistance to patients of the Unified Health System (UHS), in northeastern Brazil.

NCT ID: NCT06003010 Not yet recruiting - Clinical trials for Adolescent Idiopathic Scoliosis

Yoga for Adolescent Idiopathic Scoliosis (AIS) Patients

Start date: September 2023
Phase: N/A
Study type: Interventional

Adolescent Idiopathic Scoliosis (AIS) is defined as a three-dimensional lateral deformity of the spine. It is described with a cobb angle of greater than 10 degrees. There is no known etiology of AIS. Once the degrees of curvature become severe (greater than 45 degrees), surgical intervention (posterior spinal fusion - PSF) is often discussed. Most adolescent patients and their families opt for surgical correction to decrease future complications of severe scoliosis, such as decreased vital capacity of the lungs, potential future activity restrictions, cosmetic appearance, and self-esteem. While the patient and family are eager to undergo PSF, they do have concerns. The major concerns are pain control and their ability to return to activities. In current literature, there are many studies completed regarding pharmacologic pain control management with the use of IV patient-controlled analgesia (PCA) with opioids, narcotics, non-steroidal anti-inflammatories, muscle relaxers, Tylenol, and gabapentin. However, there is not a well-established multimodal pain management plan for postoperative PSF patients. There is also no current literature discussing nonpharmacologic pain management methods, such as stretching, strengthening and yoga, for patients undergoing PSF. There are multiple studies discussing core stabilization used for helping AIS patients non-operatively. There is no literature discussing the use of nonpharmacologic pain management methods for improved pain control (including decreased use of pharmacologic agents) and quicker return to activities. The aim of this study is to determine if patients with AIS undergoing PSF require fewer pain medications and have an earlier return to activities if completing a yoga program six weeks prior to their surgery.