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Clinical Trial Summary

SCI results in higher incidence of heart disease and diabetes and heart disease is the most common cause of death. Chronic inflammation, deleterious changes in vascular structure and impaired glucose metabolism are risk factors that contribute to both heart disease and diabetes. While exercise can help reduce these risk factors, paralysis and impaired accessibility often precludes exercise in persons with SCI. New research in able-bodied persons demonstrates passive heating decreases inflammation and improves vascular function. Similar studies in persons with SCI suggest they may also have the same health benefits however these studies only investigated the impact of short term (one episode) passive heating (as opposed to repeated bouts). Repeated bouts of heat exposure will likely be required to impact chronic inflammation, but this has never been tested in persons with SCI. This study will test the impact of repeated bouts (3x/week) of passive heat stress over a longer term (8 weeks) on inflammation, metabolism and vascular function.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT04971408
Study type Interventional
Source VA Office of Research and Development
Contact Michelle B Trbovich, MD
Phone (210) 617-5300
Email michelle.trbovich@va.gov
Status Recruiting
Phase N/A
Start date July 1, 2022
Completion date June 30, 2024

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