Clinical Trials Logo

Spinal Cord Injuries clinical trials

View clinical trials related to Spinal Cord Injuries.

Filter by:

NCT ID: NCT05605912 Recruiting - Clinical trials for Incomplete Spinal Cord Injury

Myosuit in Incomplete Spinal Cord Injury

Start date: October 3, 2022
Phase: N/A
Study type: Interventional

The Myosuit is a light-weighted lower extremity soft exosuit which provide assistance during walking. In this study the Myosuit will be tested in the home and community setting in patients with incomplete spinal cord injury.

NCT ID: NCT05601661 Recruiting - Clinical trials for Cervical Spinal Cord Injury

Safety and Feasibility of Paired Vagus Nerve Stimulation With Rehabilitation for Improving Upper Extremity Function in People With Cervical Spinal Cord Injury

Start date: July 1, 2023
Phase: N/A
Study type: Interventional

The purpose of this study is to determine the safety and feasibility of pairing vagus nerve stimulation (VNS) with rehabilitation and to determine the efficacy of pairing VNS with rehabilitation.

NCT ID: NCT05597176 Recruiting - Spinal Injuries Clinical Trials

Telemonitored Exercise to Attenuate Metabolic Dysregulation in Spinal Cord Injury

TEAM-SCI
Start date: January 13, 2023
Phase: N/A
Study type: Interventional

The purpose of this research is to test the health benefits of using functional electrical stimulation for lower extremity exercise at home.

NCT ID: NCT05593237 Recruiting - Pain, Postoperative Clinical Trials

Transcranial Magnetic Stimulation for Chronic Neuropathic Pain

Start date: April 25, 2022
Phase: N/A
Study type: Interventional

Chronic neuropathic pain is defined as pain caused by a lesion or disease of the somatosensory nervous system. It is highly prevalent, debilitating, and challenging to treat. Current available treatments have low efficacy, high side effect burden, and are prone to misuse and dependence. Emerging evidence suggests that the transition from acute to chronic neuropathic pain is associated with reorganization of central brain circuits involved in pain processing. Repetitive transcranial magnetic stimulation (rTMS) is a promising alternative treatment that uses focused magnetic pulses to non-invasively modulate brain activity, a strategy that can potentially circumvent the adverse effects of available treatments for pain. RTMS is FDA-approved for the treatment of major depressive disorder, obsessive-compulsive disorder, and migraine, and has been shown to reduce pain scores when applied to the contralateral motor cortex (M1). However, available studies of rTMS for chronic neuropathic pain typically show variable and often short-lived benefits, and many aspects of optimal treatment remain unknown, including ideal rTMS stimulation parameters, duration of treatment, and relationship to the underlying pain etiology. Here the investigators propose to evaluate the efficacy of high frequency rTMS to M1, the region with most evidence of benefit in chronic neuropathic pain, and to use functional magnetic resonance imaging (fMRI) to identify alternative rTMS targets for participants that do not respond to stimulation at M1. The central aim is to evaluate the pain relieving efficacy of multi-session high-frequency M1 TMS for pain. In secondary exploratory analyses, the investigator propose to investigate patient characteristic that are predictive of responsive to M1 rTMS and identify viable alternative stimulation targets in non-responders to M1 rTMS.

NCT ID: NCT05589415 Recruiting - Clinical trials for Spinal Cord Injuries

Targeted HD-tDCS to Improve Upper Limb Rehabilitation in SCI

Start date: November 23, 2020
Phase: N/A
Study type: Interventional

The proposed project seeks to maximize the functional recovery achieved during the rehabilitation of the paretic upper limbs in individuals with SCI. The investigation will work towards optimizing the use of transcranial direct current stimulation (tDCS), an adjunct known to improve the effectiveness of rehabilitation. In particular, the relationship between the specificity of current delivery and functional benefit will be explored, and findings may lead to a framework that can be translated to the clinic setting.

NCT ID: NCT05589402 Recruiting - Stroke Clinical Trials

Temporary Inactivation of Strong Muscle Sensation to Improve Rehabilitation Interventions in SCI

Start date: June 4, 2019
Phase: Phase 1
Study type: Interventional

The investigators are conducting a research study to try to improve rehabilitation interventions for individuals with spinal cord injury (SCI). In this study, the aim is to determine if temporarily numbing non-paralyzed arm muscles with an over-the-counter numbing cream while exercising paralyzed muscles, can improve the strength, function, and sensation of paralyzed muscles after a spinal cord injury.

NCT ID: NCT05563103 Recruiting - Clinical trials for Spinal Cord Injuries

Combination Therapy to Improve SCI Recovery.

BO2ST
Start date: January 17, 2023
Phase: N/A
Study type: Interventional

The purpose of this study is to determine how combining bouts of low oxygen, transcutaneous spinal cord stimulation, and walking training may improve walking function for people with chronic spinal cord injury.

NCT ID: NCT05556057 Recruiting - Clinical trials for Spinal Cord Injuries

Feasibility of Mindfulness Meditation Training and Home Practice in Persons With Spinal Cord Injury

Start date: December 6, 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the feasibility and acceptability of a 6-week app-guided Mindfulness meditation training (MM) intervention and health education (active control) condition in people with spinal cord injury (SCI) who have chronic pain and to examine the feasibility of data collection procedures

NCT ID: NCT05553457 Recruiting - Clinical trials for Spinal Cord Injuries

MyHand-SCI: An Active Hand Orthosis for Spinal Cord Injury

Start date: October 4, 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to develop and test the hardware and software components of the MyHand-SCI device to assist with hand function for individuals with C6-C7 spinal cord injury.

NCT ID: NCT05536076 Recruiting - Sleep Apnea Clinical Trials

Effect of Hypercapnia Treatment on Respiratory Recovery After Spinal Cord Injury

RECOV2SCI
Start date: March 1, 2023
Phase: N/A
Study type: Interventional

It is estimated that 1,275,000 people in the United States alone live with spinal cord injury, including around 100,000 Veterans with spinal cord injury, making the V.A. the largest integrated health care system in the world for spinal cord injuries injury care. New therapies are needed to prevent the morbidities and mortalities associated with the high prevalence of respiratory disorders in Veterans with spinal cord injury. The current research project and future studies would set the base for developing innovative therapies for this disorder. This proposal addresses a new therapeutic intervention for sleep apnea in spinal cord injury. The investigators hypothesized that daily hypercapnia treatments improve respiratory symptoms and alleviate sleep apnea in patients with chronic spinal cord injury. The investigators will perform a pilot study to examine the impact of daily hypercapnia treatments for-two week durations among Veterans with spinal cord injury. The investigators believe that this novel approach to treating sleep apnea and will yield significant new knowledge that improves the health and quality of life of these patients.