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Spasticity clinical trials

View clinical trials related to Spasticity.

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NCT ID: NCT04446702 Completed - Spasticity Clinical Trials

Retrospective Real-Life Study From One Brazilian Reference Center Assessing Long-Term Experience In The Treatment Of Adult Spasticity With AbobotulinumtoxinA

RETURN
Start date: March 5, 2021
Phase:
Study type: Observational

The aim of the study is to describe the long-term use of abobotulinumtoxinA (Dysport®) in adult subjects affected with upper limb spasticity (ULS) +/- lower limb spasticity (LLS) who received treatment with Dysport® for a minimum of three injections cycles at the Instituto de Medicina Física e Reabilitação do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (IMREA HC FMUSP) in Brazil.

NCT ID: NCT04340336 Completed - Spasticity Clinical Trials

Study Assessing Adult Subjects Affected With Upper and/or Lower Limb Spasticity Treated With Botulinum Neurotoxin Type A

RESULT
Start date: July 21, 2020
Phase:
Study type: Observational

The aim of the study is to describe the long term use of Botulinum Neurotoxin Type A (BoNT-A) in adult subjects affected with upper and/or lower limb spasticity who received treatment with BoNT-A for a minimum of three injections cycles at three Italian centers. The study has a retrospective design and data relating to subjects' injections cycles occurred in the past are collected. Period of observation defined in the protocol is from 2008 to 2018, but it could change for each subject according to the number of injections cycles performed. Time frame for data collection is 12 months from study start.

NCT ID: NCT04312581 Completed - Stroke Clinical Trials

Extracorporeal Shock Wave Therapy on Wrist and Hand Functions in Spastic Chronic Stroke Patients

Start date: March 21, 2020
Phase: N/A
Study type: Interventional

40 chronic stroke patients with upper limb spasticity will randomly divided into two groups. First group will receive 3 sessions of radial extracorporeal shock wave therapy (rESWT) with one week apart without cessation of current physical therapy, while the second group will continue to receive conventional rehabilitative program. Assessment will be done at baseline, 2 weeks after rESWT and 3 months after rESWT using Modified Ashworth Scale, Fugl Meyer Assessment for hand function and wrist control, motricity index for pinch grip and Hmax/ Mmax amplitude ratio of flexor carpi radialis muscle.

NCT ID: NCT03906305 Completed - Ischemic Stroke Clinical Trials

Dry Needling and Bobath Treatment Clinical Effects Focused on Stroke Patients

Start date: November 26, 2018
Phase: N/A
Study type: Interventional

The investigators aim to determine if dry needling technique in a non myofascial trigger point area generate the same changes in spasticity, function and pain responses as with dry needling in a myofascial trigger point area.

NCT ID: NCT03546517 Completed - Stroke Clinical Trials

Effectiveness of Dry Needling (DNHS Technique) in Patients With Chronic Stroke

Start date: June 19, 2018
Phase: N/A
Study type: Interventional

Study hypothesis: The DNHS technique, performed via one session of deep dry needling of myofascial trigger points applied to the biceps brachii, brachialis, flexor digitorum superficialis, flexor digitorum profundus, triceps brachii, extensor digitorum and adductor pollicis muscle is effective for decreasing spasticity and muscle stiffness (both of which are components of hypertonia) as well as for improving the upper limb function of the previously described muscles in patients with chronic cerebral vascular accident (CVA), assessed both post-intervention and after 15 days. General aims To analyse the immediate therapeutic effect of the DNHS technique and the effect at 15 days follow-up, for the following variables: - Spasticity - Muscle stiffness - Upper limb function - Patient perceived quality of life Materials and methods Population: patients from the province of Zaragoza (Spain) diagnosed with a haemorrhagic or ischemic CVA by a neurologist. Recruitment strategy: recruitment will take place via the Stroke Association in Aragon (AIDA) [Aragon Stroke Association] in the province of Zaragoza, Spain, seeing as the greater proportion of patients who have suffered a stroke and are in the chronic stage of the illness go to this centre to receive treatment. Thus, this avoids patients having to travel elsewhere for the study. Furthermore, in the case of patients who wish to participate in the study after having received information via third persons or via other means and who are not members of the Association or do not attend the centre on a regular basis, the Association AIDA has offered to allow these people to attend for free, making its facilities available and supporting the development of this study.

NCT ID: NCT03302741 Completed - Spasticity Clinical Trials

Imaging of 3D Innervation Zone Distribution in Spastic Muscles From High-density Surface EMG Recordings

Start date: November 21, 2017
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate if it is possible to use a new 3D imaging method to guide Botulinum neurotoxin (BTX) injection for muscle spasticity management after stroke. This imaging method is called three dimensional innervation zone imaging, or 3DIZI.

NCT ID: NCT03240601 Completed - Clinical trials for Spinal Cord Injuries

Spinal Cord Stimulation to Augment Activity Based Therapy

Start date: July 1, 2017
Phase: N/A
Study type: Interventional

Involuntary muscle activity, often called spasticity, is a common problem following spinal cord injury (SCI) that can make it hard to move. Many things can cause spasticity including: muscle stretch, movement, or it can happen for no reason, and it is often described as an uncontrolled muscle spasm or feeling of stiffness. Drugs are typically used to treat spasticity, but they often have side effects, like muscle weakness, which can add to movement problems. Rehabilitation therapies offer alternatives to drugs for treating involuntary muscle activity, and rehabilitation can also improve daily function and quality of life. These benefits may be greater when several rehabilitation therapies are used together. Walking ability can be improved with a type of therapy called "locomotor training". This type of therapy may also have the benefit of decreasing spasticity. When locomotor training (LT) is combined with electrical stimulation, the benefits of training may be increased. In this study, investigators will use a kind of stimulation called transcutaneous spinal cord stimulation ("TSS") to stimulate participants' spinal cord nerves during locomotor training.

NCT ID: NCT03129529 Completed - Spasticity Clinical Trials

Comparing the Effect of Focused and Radial Extracorporeal Shock Waves on Post-stroke Hypertonia

Start date: January 1, 2016
Phase: N/A
Study type: Interventional

The main purpose of this study is to compare treatment efficacy of focused and radial extracorporeal shock waves on spasticity in chronic stroke patient

NCT ID: NCT02718690 Completed - Spasticity Clinical Trials

Importance of the Current Density in TENS

Start date: December 2014
Phase: N/A
Study type: Interventional

The purpose of this study is demonstrate the importance of density current of TENS in the effect about H-reflex in healthy volunteers.

NCT ID: NCT02566837 Completed - Spasticity Clinical Trials

Use of Ultrasound in Injections of Botulinum Toxin

TOXINECHO
Start date: February 2012
Phase: N/A
Study type: Interventional

Intramuscular injections of botulinum toxin are currently the best focal treatment of spasticity, with clearly defined indications and role. French and European recommendations focus on the toxin's mode of administration, which must be as precise as possible. The toxin's specific action on motor endplates (blocking the release of acetylcholine) shows the importance of targeted injections within the muscle belly. The pain caused by these injections is due partly the number of injections (up to 30 in a single session), and partly to the use of electrical stimulation guidance. Prevention and alleviation of the pain caused by these injections have become a regulatory obligation since the law of 4 March 2002 relating to the rights of patients and the quality of the health system (" Any person has the right to receive relief from pain, which must, under all circumstances, be prevented, evaluated, taken into account and treated … ").