Stroke Clinical Trial
Official title:
Using Shear Wave Ultrasound Elastography for Follow up After Anti-spastic Intervention Among Stroke Patients
Spasticity of stroke patient, a very common complication in clinical practice, affects
performance of hand function and gait pattern. It also interferes with quality of life of
patients severely. Currently first line clinical approach to spasticity consist of physical
therapy and pharmacological management. However, there are still some refractory cases that
needed local intervention such as Botox injection.
So far, we only can use subjective methods to measure muscle tension, such as modified
Ashworth scale and Tone Assessment Scale. In our previous study, we found that ultrasound
shear wave image could correlate with muscle stiffness caused by poststroke spasticity. With
this new method, we aim to establish a more objective method in measuring abnormal poststroke
muscle tension before and after treatments and further monitor therapeutic effect. We also
include several assessment scales to evaluate the correlation between measured muscle spasm
and activity of daily living.
We hypothesize that the rheological changes in muscles muscle spasm after Botox injection can
be detected by ultrasound shear wave image. Therapeutic effect can also be seen in its effect
on daily functions.
In this project, we will use shear wave imaging of ultrasound to investigate the elasticity
(and hardness) of the biceps brachii and brachialis muscle in stroke patients with unilateral
hemiplegia before and after Botox injection. The findings of this project will provide the
objective evaluation of muscle spasticity and its correlation with functional status, which
will provide new points of view toward treatment of spasticity.
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