Clinical Trials Logo

Clinical Trial Summary

Three-dimensional gait analysis (3DGA) is the 'gold standard' for measurement and description of gait. Gait variability can arise from intrinsic and extrinsic factors and may vary between walking conditions. This study aimed to define the inter-trial (intrinsic) and inter-session (extrinsic) repeatability in gait analysis data of children with CP who were walking in four conditions, namely barefoot or with ankle-foot orthosis, and overground or treadmill.


Clinical Trial Description

With a prevalence of two to three per 1000 live births, Cerebral Palsy (CP) is the most common motor disability of childhood. Improving disturbed gait in ambulatory children with CP is an important treatment goal because it is associated with functional independence and participation of children in the society. It is a common practice to prescribe ankle-foot orthoses (AFO) for ambulatory children to improve their gait, prevent secondary deformities, provide an improved base of support, and compensate for muscle weakness. Three-dimensional gait analysis (3DGA) is the 'gold standard' for measurement and description of gait. However, gait variability can arise from intrinsic (i.e., caused by the person's natural gait variability) and extrinsic (i.e., methodological sources, such as marker placement errors) factors and may vary between walking conditions. Follow-up and/or pre- and post-intervention 3DGA's are used to determine the treatment for these children with CP. So, it is important to know when differences between 3DGA's can be seen as 'true differences' or when the difference can be explained by intrinsic/extrinsic gait variability. The purpose of the current study is to quantify the repeatability of gait in children with CP. Therefore, the repeatability between two 3DGA's that are performed at the Clinical Motion Analysis Laboratory (CMAL) of UZ Leuven will be assessed, following the standard 3DGA procedure that is applied at CMAL for routine clinical follow-up. On the first test day, subjects will first receive a standard clinical examination preceding the clinical overground 3DGA that is planned as a routine clinical follow-up at the CMAL, extended with an additional 3DGA on the treadmill. The treadmill gait laboratory and overground gait laboratory are across the hall from each other, which makes it possible for the subject to walk from one to the other gait laboratory in just a minute. On the second test day, a repeated 3DGA overground and on the treadmill will be performed by the same clinician. This involved clinical assessor is well-trained to perform 3GDA in children with CP. Between the measurements, a period from 1 - 14 days is foreseen. The combinations of repeated gait trials per test day, and the repeated test days, with involvement of only one assessor, facilitates the distinction between intrinsic and extrinsic variability. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT06355869
Study type Observational
Source Universitaire Ziekenhuizen KU Leuven
Contact
Status Completed
Phase
Start date August 17, 2021
Completion date May 31, 2023

See also
  Status Clinical Trial Phase
Recruiting NCT05571033 - Operant Conditioning of the Soleus Stretch Reflex in Adults With Cerebral Palsy N/A
Completed NCT00011024 - Prospective Studies of the Use of Self Hypnosis, Acupuncture and Osteopathic Manipulation on Muscle Tension in Children With Spastic Cerebral Palsy Phase 2
Recruiting NCT05810779 - Dynamic Surface Exercise and Trunk Targeted Training in Children With Spastic Cerebral Palsy N/A
Completed NCT01049581 - Effects of Pediatric Aquatic Therapy in Children With Spastic Cerebral Palsy N/A
Completed NCT04634136 - Full-spectrum Medical Cannabis for Treatment of Spasticity in Patients With Severe Forms of Cerebral Palsy N/A
Recruiting NCT06070233 - Radiosurgery Treatment for Spasticity Associated With Stroke, SCI & Cerebral Palsy N/A
Completed NCT01815814 - Therapeutic Potential of Myofascial Structural Integration in Children With Cerebral Palsy N/A
Recruiting NCT05113433 - Effects of Different Time Period of Standing Frame on Spasticity and Gait in Children With Spastic Cerebral Palsy. N/A
Recruiting NCT03676439 - Lateral Cord Magnetic Stimulation For Refractory Spastic Cerebral Palsy Phase 2/Phase 3
Completed NCT03708757 - Effect of Post Isometric Relaxation Technique & Eccentric Muscle Contraction on Hamstring Spasticity in CP N/A
Not yet recruiting NCT03529682 - Circuit Training in Children With Cerebral Palsy N/A
Not yet recruiting NCT06407856 - Dual Task Training in Spastic Cerebral Palsy N/A
Not yet recruiting NCT06407921 - Whole Body Vibration and BOSU Ball in Spastic Cerebral Palsy N/A
Not yet recruiting NCT06407869 - Effects of Functional Progressive Strength Training in Children With Spastic Cerebral Palsy N/A
Completed NCT04078321 - Evaluation of Multifocal Transcutaneous Electrical Stimulation for Self-treatment Among Children With Cerebral Palsy N/A
Active, not recruiting NCT06330311 - Effectiveness of Whole-Body Vibration N/A
Terminated NCT00955877 - Extended-release Epidural Morphine for Acute Post-operative Analgesia Following Selective Dorsal Rhizotomy in Children N/A
Completed NCT02359799 - Robotic Rehabilitation of Cerebral Palsy N/A
Not yet recruiting NCT05340439 - INcobotulinumtoxina in ChIldren Upper and Lower Limb sPasticITy (INCIPIT) Phase 2
Completed NCT01147653 - A Randomized Study of Autologous Umbilical Cord Blood Reinfusion in Children With Cerebral Palsy Phase 2