Trial of DFP-14927 in Advanced Solid Tumors

Status Recruiting

Clinical Trial Summary

This is a Phase I, open-label, single-arm, dose escalation study of DFP-14927 intravenous infusion administered to patients with refractory or relapsed solid tumors.

Clinical Trial Description

This study will determine the safety and efficacy of DFP-14927 in patients with refractory or relapsed advanced solid tumors. The study will be guided by a standard "3+3"dose escalation by observing the drug-related toxicities and dose-limiting toxicities following weekly IV infusion of DFP-14927 for each 28-day cycle (4 doses per cycle). In addition, the maximum-tolerated dose and recommended Phase II dose for DFP-14927 will be determined. Furthermore, the study will determine the pharmacokinetics and bioavailability of DFP-14927 during the first cycle of treatment using the weekly dosing schedule. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03943004
Study type	Interventional
Source	Delta-Fly Pharma, Inc.
Contact
Status	Recruiting
Phase	Phase 1
Start date	September 30, 2019
Completion date	December 1, 2024

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