Soft Tissue Ultrasound of Infections

Status Completed

Clinical Trial Summary

Objectives:

This study aims to characterize severe skin and soft tissue infections (SSTIs) in the emergency department through the acquisition of ultrasound images. A wide range of SSTIs will be imaged and recorded, leading to a registry of these infections. The registry will show whether ED (emergency department) sonographers can accurately characterize these infections, as compared to the final hospital diagnosis. The registry will also provide data for a case-control study comparing ultrasonographic characteristics of necrotizing skin and soft tissue infections (NSTIs) to those of non-necrotizing SSTIs.

Research procedures:

In this study, the investigators will approach patients who present to the Emergency Department with a possible skin and/or tissue infection. Study subjects must be ED patients requiring admission to the hospital for the primary problem of an SSTI due to the need for follow-up. If the patient consents to participating in the study, the investigator will obtain and record an ultrasound image of the infected area. An ultrasound image of an uninfected area of skin will also be recorded for comparison. Patient information regarding personal history, physical examination, blood tests and x-rays will also be gathered from participants.

Clinical Trial Description

n/a

Study Design

Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Diagnostic

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01557426
Study type	Interventional
Source	Rhode Island Hospital
Contact
Status	Completed
Phase	Phase 1
Start date	March 2012
Completion date	March 2015

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT02864420` - Hospitalization at Home: The Acute Care Home Hospital Program for Adults	N/A
Completed	`NCT00746109` - Study of Wound Packing After Superficial Skin Abscess Drainage	Phase 4
Completed	`NCT03296280` - Evaluation of Implementation of a National Point-of-Care Ultrasound Training Program
Completed	`NCT01876628` - Adjunctive Clindamycin for Cellulitis: C4C Trial.	Phase 4
Not yet recruiting	`NCT01947660` - Continuous Regional Anesthesia for Septic Limb Orthopedic Surgery	N/A
Active, not recruiting	`NCT01706913` - Study Assessing Impact of Dermatology Consultation for Patients Admitted With Cellulitis	N/A
Completed	`NCT03474523` - Effectiveness of Diathermy-Radiofrecuency Compared With Cavitation in Cellulitis Treatment	N/A
Recruiting	`NCT03312946` - Effect of Vibro-oscillatory Therapy for Improvement of Body Contour and Appearance of Cellulite.	N/A
Active, not recruiting	`NCT05226260` - Decreasing Antibiotic Duration for Skin and Soft Tissue Infection Using Behavioral Economics in Primary Care	N/A
Active, not recruiting	`NCT03785834` - The Effect of Histopathologic Analysis and Tissue Cultures on Inpatient Management of Cellulitis and Pseudocellulitis
Completed	`NCT01549613` - Evaluation of Daptomycin for the Emergency Department Treatment of Complicated Skin and Skin Structure Infections	Phase 4
Completed	`NCT01029782` - Comparison of Intravenous Cefazolin Plus Oral Probenecid With Oral Cephalexin for the Treatment of Cellulitis	Phase 2
Completed	`NCT00676130` - Study of New Antibiotic Regimen for the Treatment of Uncomplicated Cellulitis in Emergency Department Patients	N/A
Not yet recruiting	`NCT03917134` - Prevention of Vaginal Cellulitis or Vaginal Cuff Abscess After Laparoscopic Hysterectomy	N/A
Completed	`NCT02230813` - Predictors of Oral Antibiotic Treatment Failure in Emergency Department Patients With Cellulitis	N/A
Completed	`NCT01339091` - Efficacy and Safety of Dalbavancin for the Treatment of Acute Bacterial Skin and Skin Structure Infections	Phase 3
Completed	`NCT00984022` - Aquacel Versus Iodoform Gauze for Filling Abscess Cavity Following Incision and Drainage	Phase 2
Completed	`NCT04091672` - RECELL® System Combined With Meshed Autograft for Reduction of Donor Skin Harvesting in Soft Tissue Reconstruction	N/A
Completed	`NCT05023200` - The Personalised Antibiotic Duration for Cellulitis (PAD-C) Study
Terminated	`NCT02087527` - Use of Corticosteroids in Children With Cellulitis	N/A