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Snoring clinical trials

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NCT ID: NCT01849406 Completed - Snoring Clinical Trials

Effect of Nasal Steroids in Snoring Intensity

Start date: April 2013
Phase: Phase 1
Study type: Interventional

It is anecdotally well known that patients snore more when their nose is blocked. However, the therapeutic effect of improving nasal airway patency on snoring indices remains a point of conjecture. Indeed, Braver et al examined the effect of a nasal vasoconstrictor and failed to show any improvement in the number of snores after its application, although apnoea-hypopnoea index (AHI)seemed to decrease. Furthermore, Hoffstein et al documented that dilation of the anterior nares in patients without nasal pathology has a relatively weak effect on snoring, and routine use of nasal dilating appliances was not recommended for the treatment of snoring. In contrast to the aforementioned studies, intranasal corticosteroids have been shown to improve sleepiness and reduce AHI in patients with obstructive sleep apnea (OSA) implying that there might be an equivalent result for the use of nasal steroids on snoring indices. Additionally, the present authors have demonstrated a strong correlation between apnoea-hypopnoea index and oral/oro-nasal breathing epochs in patients with OSA and normal nasal resistance and that nasal surgery is effective only in OSA patients who preoperatively have decreased nasal breathing epochs. It is plausible thus to suggest that snoring severity, in equivalence to OSA severity, might be associated to oral/oro-nasal breathing epochs and that improving nasal patency by nasal steroids might also increase nasal breathing epochs and lead to decreased snoring indices in patients who had decreased nasal breathing before the administration of nasal steroids. Patients will be randomized in two groups: the patients of the first group will undergo a one week therapy of nasal budesonide, then two weeks of washout period, and thereafter one week of nasal normal saline. The patients of the second group will undergo a one week therapy of nasal normal saline, then two weeks of washout period, and thereafter one week of nasal budesonide. Before and after each treatment regimen patients will undergo an assessment, which will consist of anterior rhinomanometry and polysomnography with concomitant measurement of snoring indices and breathing route pattern. The investigators hypothesize that the application for one week of nasal budesonide has a beneficial effect on snoring indices in patients who present before the application decreased proportion of nasal breathing epochs and in whom nasal budesonide succeeded in increasing nasal breathing epochs.

NCT ID: NCT01772017 Terminated - Clinical trials for Obstructive Sleep Apnea

A Trial to Evaluate a Device for the Treatment of OSA and Snoring

OPEN
Start date: October 2012
Phase: N/A
Study type: Interventional

To evaluate the safety and efficacy of the Tongue Advancement Retainer Device in treating subjects with Obstructive Sleep Apnea (OSA) and snoring.

NCT ID: NCT01680380 Withdrawn - Clinical trials for Sleep Apnea Syndromes

Tracking Breathing During Sleep With Non-contact Sensors

Start date: October 2012
Phase: N/A
Study type: Observational

The purpose of this study is to evaluate the feasibility of tracking breathing during sleep with non-contact sensors (for example, microphones or wireless movement sensors). The investigators will use the data collected with these sensors to develop algorithms for tracking breathing during sleep. The investigators will assess the performance of the algorithms by comparing automatic output against manually-generated labels.

NCT ID: NCT01561703 Recruiting - Snoring Clinical Trials

Comparing Healthcare Utilization Between Adenotonsillectomy Patients With and Without Postoperative Antibiotic Use

Start date: March 2012
Phase: N/A
Study type: Interventional

This study is designed to look at healthcare utilization following the removal of tonsils and adenoids in pediatric patients who are not given an antibiotic following surgery.

NCT ID: NCT01554904 Completed - Sleep Apnea Clinical Trials

Study Will Test the Theory That Training With the Facial-Flex Exercise Device Will Improve Snoring in Patients

Start date: February 2012
Phase: N/A
Study type: Interventional

The study will test the hypothesis that training with the Facial-Flex exercise device for six weeks will improve snoring in patients with primary snoring or very mild sleep apnea.

NCT ID: NCT01515371 Terminated - Habitual Snoring Clinical Trials

Dose Finding Study for a Botulinum Toxin Type A Injection to Treat Habitual Snoring

Start date: January 2012
Phase: Phase 2
Study type: Interventional

The purpose of this study is to identify out of up to three doses a safe and effective dose of Botulinum toxin type A for an injection into one side of the soft palate to treat snoring.

NCT ID: NCT01491828 Completed - Sleep Apnea Clinical Trials

Study to Determine Results of Vibratory Stimulus on Subject's Neck

Start date: November 2011
Phase: Phase 1
Study type: Interventional

This study will validate whether an external vibratory stimulus applied to a subject's neck causes head, neck or jaw movement.

NCT ID: NCT01322334 Completed - Clinical trials for Obstructive Sleep Apnea

Singing Exercises to Improve Symptoms of Snoring and Sleep Apnea

Start date: November 2005
Phase: N/A
Study type: Interventional

Upper airway resistance during sleep can present with a range of symptoms from simple snoring (SS) through to severe obstructive sleep apnea (OSA). Pharyngeal narrowing or collapse leads to reduction or cessation in airflow during sleep, and is associated with loud snoring. The investigators hypothesized that regular singing exercises could strengthen pharyngeal muscles and/or increase their resting tone, and lead to an improvement of symptoms and thus quality of life in patients with all forms of snoring.

NCT ID: NCT01223859 Completed - Snoring Clinical Trials

Pretreatment Assessment of Oropharynx Ans Soft Palate Radiofrequency Surgery - a Multi-center Study

Start date: January 2008
Phase: N/A
Study type: Interventional

Interstitial radiofrequency (RF) surgery of the soft palate (SP) is an established option in the treatment of habitual snoring. The decision making process in the management of habitual snoring would benefit from diagnostic guidelines for oropharyngeal findings. The aim was to investigate the correlation of systematic clinical pretreatment oropharyngeal examination scores with the efficacy of interstitial RF surgery of SP in a multi-center study

NCT ID: NCT01175421 Completed - Sleep Apnea Clinical Trials

Multidimensional System as Predictor of Outcomes in Obstructive Sleep Apnea: The OSA-SCORE

OSA-SCORE
Start date: May 2010
Phase: N/A
Study type: Observational

Purpose: In a retrospective cohort the investigators will validate, the goodness of a multidimensional index to classified the severity of patients with sleep disordered breathing that has been previously developed in a prospective longitudinal cohort.