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Snoring clinical trials

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NCT ID: NCT05325489 Not yet recruiting - Snoring Clinical Trials

Comparison of Nebulized Budesonide and Intranasal Budesonide Spray in Children With Adenotonsillar Hypertrophy

Start date: April 2022
Phase: Phase 3
Study type: Interventional

Budesonide is one of the most common drugs uesd in children with adenotonsillar hypertrophy. This study aim to evaluate the efficacy of a short course of budesonide inhalation suspension via transnasal nebulization in children with adenotonsillar hypertrophy. The second aim is to compare budesonide inhalation suspension with budesonide aqueous nasal spray in adenotonsillar hypertrophy treatment.

NCT ID: NCT05116657 Not yet recruiting - SARS-CoV2 Infection Clinical Trials

Obstructive Sleep Apnoea Post Covid 19: Role of the Upper Airway Microbiome

Start date: November 22, 2021
Phase:
Study type: Observational

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) causing coronavirus disease, Covid-19, has spread rapidly across the globe since its emergence in January 2020. As of January 2021, there are 87.6 million confirmed cases worldwide, with 1.9milion deaths. In conjunction with this high disease incidence, there have also been reports of Covid-19 related sleep disordered breathing, with up 18% in a Chinese study and 57% in an Italian study of individuals with Covid-19 reporting sleep disturbance. Obstructive Sleep Apnea (OSA) is a common, chronic condition due to partial or complete upper airway collapse during sleep. OSA is more common in males & obese individuals, both of which are more adversely affected by SARS-CoV-2 infection. Furthermore, inflammation of the upper airway, or nasal passages leading to congestion could lead to a compromised upper airway during sleep and subsequently, obstructive sleep apnea. We believe that's SARS -CoV-2 infection, and subsequent Covid-19 will lead to an altered microbiome in the upper airway. This is turn will lead to worsening nasal inflammation and congestion, which could predispose individual with previous Covid-19 disease to OSA. Additionally, OSA is treated with Continuous Positive Airway Pressure (CPAP) a machine which delivers pressurized air into the upper airway via a face mask. This keeps the upper airway open during sleep. When CPAP is well tolerated by individuals, it works well to reduce the symptoms of OSA. Unfortunately, many patients find it difficult to tolerate CPAP. One reason often reported for poor tolerance is nasal congestion. We believe that an altered upper airway microbiome, due to previous SARS-CoV-2 infection, will affect treatment adherence to CPAP therapy. Secondly, we will investigate if treatment with CPAP therapy causes any change in the upper airway microbiome.

NCT ID: NCT04324671 Not yet recruiting - Snoring Clinical Trials

Upper Airway Obstruction in Non-obese Patients With Snoring and Obstructive Sleep Apnea

Start date: July 1, 2020
Phase:
Study type: Observational

This study aims at :- 1. detecting the prevelance of snoring and OSA in non-obese patients 2. identify their diagnostic profile in order to provide proper management

NCT ID: NCT04250584 Not yet recruiting - Sleep Apnea Clinical Trials

Substantial Equivalence of iSlprâ„¢ and SomnoDent® Classic in the Treatment of Snoring and Mild to Moderate Sleep Apnoea.

Start date: March 2020
Phase: N/A
Study type: Interventional

The study is a thirty three week, prospective, open-label, randomized, parallel-group non-inferiority study. The study aims to investigate the Substantial Equivalence of a novel mandibular device called iSlprâ„¢, produced by BioAnalytics, to a currently approved device, SomnoDent® Classic, in the treatment of mild to moderate Obstructive Sleep Apnoea (OSA) and snoring.

NCT ID: NCT04143022 Not yet recruiting - Snoring Clinical Trials

Evaluation of the Effects of Acupuncture Press Needle in Mild to Moderate Obstructive Sleep Apnea Patients

Start date: October 23, 2019
Phase: N/A
Study type: Interventional

The aim of this study is to investigate the effects of acupuncture press needle in mild to moderate obstructive sleep apnea patients.

NCT ID: NCT03890549 Not yet recruiting - Snoring Clinical Trials

Validation of Downloadable Mobile Snore Applications by Polysomnography (PSG)

Start date: April 1, 2019
Phase:
Study type: Observational

The aim of this study is to validate the downloadable mobile snore applications by polysomnography.

NCT ID: NCT00399451 Not yet recruiting - Apnea Clinical Trials

Polidocanol Sclerotherapy of Pharynges for Obstructive Sleep Apnea (OSA) and Snoring Subjects(SS)

Start date: December 2006
Phase: Phase 1/Phase 2
Study type: Interventional

The aim of this prospective study is to evaluate the results of polidocanol sclerotherapy of pharynx for OSAS & SS,to reduce pharyngeal compliance.