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Snoring clinical trials

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NCT ID: NCT03893552 Completed - Clinical trials for Sleep Apnea Syndromes

Upper Airway Stability During Wakefulness and Sleep

Start date: March 1, 2016
Phase: N/A
Study type: Interventional

Negative expiratory pressure is a technique that has been the focus of many studies in the last few years. Airway response to the application of a negative expiratory pressure (NEP) can be used to detect the presence of upper airway collapsibility. In normal subjects, an increase in expiratory flow is observed while in patients with collapsible upper airway, the flow will show a transient decrease due to airway collapse. The objectives of this study will be initially to investigate the diagnostic utility of this technique as a noninvasive measurement of the stability of the upper airway in sleep-related breathing disorders. Secondly, we aim to see the sites of airway obstructions, discovered by NEP, through nasal endoscopy. Finally, we aim at testing the utility of NEP technique in the evaluation of therapeutic response. For this purpose, we will apply it in patients before and after airway stabilization interventions like ENT surgery, oropharyngeal exercises, orthodontic mandibular advancement electrical stimulation of the hypoglossal nerve.

NCT ID: NCT03829956 Completed - Clinical trials for Obstructive Sleep Apnea

Intraoral Tongue Stimulation for Treatment of Primary Snoring

Start date: February 4, 2019
Phase: N/A
Study type: Interventional

Intraoral Neuromuscular Training for Treatment of Snoring Objective Studies show that improving pharyngeal muscle tone can ameliorate obstructive sleep apnoea (OSA) and snoring. The study uses an intra-oral stimulation device (SnooZeal) aimed at a population of snorers. The aim of this study is to assess the efficacy of intra-oral neuromuscular stimulation training during wakefulness on snoring. Methods This is a prospective study, recruiting up to 200 patients from the sleep clinics. In this study, subjects will use the intra-oral stimulation device once a day for 20 minutes each time for a period of 6 weeks. During these 6 weeks, subjects will complete a daily diary of the device use and any side effects or adverse events. Partners also complete a daily snoring score. Subjects will be followed-up for a further 2 weeks after treatment. They will complete Pittsburgh Sleep Quality Index (PSQI) and subjective sleep quality questionnaires for a further 2 weeks. Partners will also complete the post treatment snoring scores. Sleep study will be repeated. Outcome measures The objective evaluation will be based on pre- and post-treatment sleep studies, visual analogue scale (VAS) snoring scores, PSQI and subjective sleep quality questionnaire. All side effects and adverse events will be reported and acted upon according to the risk management structure.

NCT ID: NCT03720353 Completed - Snoring Clinical Trials

Pharmacological Intervention for Symptomatic Snoring

Start date: December 17, 2018
Phase: Phase 1/Phase 2
Study type: Interventional

Currently, there is no pharmacological intervention capable of maintaining airway patency for the treatment of snoring and airflow limitation during sleep. Here we study the effect of pharmacological stimulation of the pharyngeal muscles on snoring severity, in a randomized quadruple-blind, crossover study.

NCT ID: NCT03640793 Completed - Clinical trials for Obstructive Sleep Apnea

Prospective Evaluation of a Palato-Pharyngeal Implant System (PPIS) Obstructive Sleep Apnea Syndrome (OSAS)

Start date: October 9, 2017
Phase: N/A
Study type: Interventional

Prospective Evaluation of a Palato-Pharyngeal Implant System (PPIS) for the Treatment of Snoring and Obstructive Sleep Apnea Syndrome (OSAS): A Pilot Study.

NCT ID: NCT03510403 Completed - Clinical trials for Obstructive Sleep Apnea

Efficacy, Safety and Acceptability of Nastentâ„¢ in Snoring and Obstructive Sleep Apnea

Start date: April 12, 2018
Phase: N/A
Study type: Interventional

This study evaluates the efficacy, the tolerance and the acceptability/compliance of the nasal airway stent, Nastent, for the treatment of mild to moderate OSA and snoring in European adult patients without cardiovascular and/or respiratory comorbidities/disorders.

NCT ID: NCT03398044 Completed - Hearing Loss Clinical Trials

Administration of Dexamethasone in PONV Prophylaxis in Children Undergoing Adenotomy

Start date: January 1, 2017
Phase: N/A
Study type: Interventional

Adenotomy, together with tonsillectomy, belongs among the most frequently performed surgical procedures in paediatric patients. These surgical procedures are associated with the second highest incidence of post-operative nausea and vomiting (PONV) (following strabism correction surgery) in paediatric surgery. PONV is associated, apart from the discomfort for the child, with a number of complications: dehydration, metabolic disruption or danger of haemorrhage and aspiration of the gastric content. Adenotomy is a typologically completely different surgical procedure, with a different target structure of the surgery, and the length and invasiveness of the procedure. Thus, it is possible to expect a difference in PONV incidence when compared to tonsillectomy. Adenotomy is a surgical procedure performed namely in children of the pre-school age. This is associated, among others, also with the problem of objectivization of post-operative nausea, which is very difficult to verbalize in small children, being a subjective feeling of body discomfort. It is possible to expect that the overall incidence of PONV will be significantly underestimated.

NCT ID: NCT03333876 Completed - Snoring Clinical Trials

In Home Assessment of Three Anti-Snoring Devices, a Cross Over Study

Start date: October 9, 2017
Phase: N/A
Study type: Interventional

Silent Night is a solution for primary snorers to guide them to the proper anti-snoring solution. It consists of a mobile application, which had an intake questionnaire, guides users to one of three anti-snoring solutions; a nasal dilator called, Mute (Rhinomed, Australia), a mandibular advancement device called myTAP V (Airway Management, Austin, TX) and a Sleep Positional Trainer SPT (SPT) (NightBalance, Netherlands). The Silent Night app also records snoring through the night and provides feedback to the user via a "snore score."

NCT ID: NCT03264963 Completed - Snoring Clinical Trials

Upper Airway Training for Treatment of Snoring

Start date: December 15, 2016
Phase: N/A
Study type: Interventional

The objective of this study is to reduce the incidence or intensity of snoring in a patient population of known simple snorers without sleep apnea using smartphone based application which allows participants to play voice controlled games using various articulations resulting in tongue base movements.

NCT ID: NCT03128307 Completed - Snoring Clinical Trials

OTC Mouthpiece for Snoring

Start date: April 7, 2017
Phase: Phase 3
Study type: Interventional

Online patient registration to participate in clinical trial to test OTC mouthpiece that controls position of the tongue to reduce snoring.

NCT ID: NCT03083106 Completed - Snoring Clinical Trials

Snoring Intervention Via Elevoplasty in a Non-surgical Clinical Environment

SILENCE
Start date: March 3, 2017
Phase: N/A
Study type: Interventional

Single Group Compared to Baseline, Non-Randomized, Multi-Center, Prospective Safety & Efficacy Study