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Smoking clinical trials

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NCT ID: NCT00181818 Completed - Clinical trials for Myocardial Infarction

Bupropion for Hospitalized Smokers With Acute Cardiovascular Disease

Start date: October 1999
Phase: Phase 4
Study type: Interventional

The purpose of the study is to test the efficacy and safety of bupropion SR for smokers hospitalized with acute cardiovascular disease.

NCT ID: NCT00181792 Completed - Smoking Clinical Trials

Family Risk Analysis of Substance Use in Attention Deficit Hyperactivity Disorder (ADHD) Youth Treated With Concerta

Start date: May 2005
Phase: Phase 4
Study type: Observational

The researchers will study 100 families over three years, each with a child (proband) between the ages of 12-17, with the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) diagnosis of ADHD. The researchers hypothesize smoking will be familial and ADHD probands with a family history of tobacco use will be at increased risk for early initiation and persistence of smoking, compared to ADHD probands with no family history of tobacco use.

NCT ID: NCT00169390 Completed - Pregnancy Clinical Trials

Monoamine Oxidases in Smoking Pregnant Women and Newborns

Start date: March 2004
Phase: N/A
Study type: Observational

Smoking substantially inhibits the activities of both monamine oxidase (MAO) A and B enzymes. Aims of this study: to compare MAO activities and nicotine and cotinine in peripheral blood of smoking and nonsmoking pregnant women, in their placenta and in cord blood and relate them with the behavior of their newborns being observed during 48 hours after birth.

NCT ID: NCT00169260 Completed - Smoking Clinical Trials

Proactive Health Intervention for Tobacco Users (Get PHIT)

Start date: February 2005
Phase: Phase 2/Phase 3
Study type: Interventional

The goal of this study is to understand how information about smokers' health risks affects their attitudes, mood, and behavior.

NCT ID: NCT00159315 Completed - Asthma Clinical Trials

ATP/AMP Challenge in Healthy Non-smokers, Smokers, Patients With Asthma, and Patients With Chronic Obstructive Pulmonary Disease (COPD)

Start date: October 2002
Phase: N/A
Study type: Interventional

In this randomised, cross-over, controlled study, a total of 84 subjects will be included: 12 healthy non-smoking volunteers; 12 current smokers; 30 patients with mild steroid-naïve asthma; and 30 patients with mild-moderate COPD. Each subject will have 1 screening visit (if necessary) and 2 study visits. At visits 2 and 3 the effects of adenosine 5'-triphosphate (ATP) or adenosine 5'-monophosphate (AMP) challenge, given in a random order, will be tested.

NCT ID: NCT00156702 Completed - Smoking Clinical Trials

Researching the Youth Smoking Experience

Start date: January 2001
Phase: Phase 1
Study type: Interventional

The primary hypothesis of this pilot study is that dependence can be prevented in adolescents who smoke, but who are not yet dependent. With this study, we seek to develop and test the feasibility and provide controlled comparisons of two brief smoking dependence-prevention interventions: motivational interviewing with feedback versus a video control. Forty adolescents between the ages of 12 and 18 will be enrolled. The evaluation and dependence-prevention phases will occur during a single 3- to 4-hour session, and the 30-45 minute follow-up sessions will take place approximately one month, three months, six months, and one year after the completion of the evaluation and dependence prevention phases.

NCT ID: NCT00136279 Completed - Smoking Clinical Trials

Linking Lives: Building Quality Parent Components for School-Based Health Programs in Middle Schools

Start date: January 2004
Phase: N/A
Study type: Interventional

The purpose of this study is to develop and evaluate the effectiveness of a parent-based intervention that can be implemented in conjunction with existing school-based programs designed to prevent or reduce sexual risk behavior or to prevent or reduce tobacco use in young adolescents. The parent programs are expected to have effects on adolescent behavior over and above the effects of the school-based programs.

NCT ID: NCT00129246 Completed - Smoking Clinical Trials

Low-Dose Naltrexone Combined With Bupropion to Stop Smoking With Less Weight Gain

Start date: December 2004
Phase: Phase 1/Phase 2
Study type: Interventional

This study will test a combination of the drugs naltrexone and bupropion with weight-concerned smokers to investigate whether or not this combination of drugs improves smoking cessation quit rates and minimizes post quit weight gain.

NCT ID: NCT00123682 Completed - Smoking Clinical Trials

TeleQuit Smoking Cessation Program

Start date: May 2005
Phase: N/A
Study type: Interventional

TeleQuit is a group randomized trial testing whether a telephone care coordination program increases the rate of smoking cessation treatment for VA patients at study sites. We are testing whether proactive care coordination (counselor initiates the call to the patient) is more effective than reactive coordination (coordinator waits for the patient to call); and whether multi-session counseling is more effective than brief primary care-based counseling plus self-help materials. We randomly assigned study sites to either quitline counseling or brief counseling only. All patients receive brief smoking cessation counseling from their primary care physician, smoking cessation medications (once they are in contact with the VA care coordinator), and a follow-up call at 6 months. Care coordination will be provided by VA clinical staff. Intensive counseling is provided by the California Smokers' Helpline.

NCT ID: NCT00121368 Completed - Smoking Clinical Trials

GN Tobacco Use Survey

Start date: February 2004
Phase: N/A
Study type: Observational

Smoking can contribute to many health problems for mothers and their babies. In developing countries, there is little information about the number of pregnant women that smoke and the reasons why some pregnant women choose to smoke. The purpose of this multi-site tobacco use survey is to obtain information on knowledge, attitudes and behaviors among pregnant women in diverse populations regarding tobacco products.