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NCT ID: NCT00273793 Completed - Smoking Clinical Trials

Increasing Contingency Management Success in Smoking Cessation

Start date: June 2005
Phase: N/A
Study type: Interventional

Incentives can be used to facilitate the acquisition of many healthy behaviors, such as smoking cessation. However, there is much room for improvement in the use of incentives. This study investigates how two aspects of providing incentives influence the effectiveness of using incentives to promote smoking cessation. One aspect is the criterion for providing incentives, e.g., whether to require smoking cessation before providing an incentive or to provide incentives following smoking reductions. The other aspect being investigated is whether it is best to use a fixed incentive amount or an amount that increases with continued cessation success.

NCT ID: NCT00273156 Completed - Smoking Clinical Trials

A Brief Dental Office Intervention With Tobacco Quitline

Start date: February 2005
Phase: Phase 3
Study type: Interventional

The novel and exploratory nature of this intervention relates to the concept of incorporating patient-specific oral health information obtained during a dental hygiene visit into the tobacco quitline counseling. Linking the patient-specific oral health information obtained during the dental hygiene visit to the tobacco quitline counseling will close the therapeutic loop for oral health professionals and make them a focal point for the tobacco use intervention without increasing clinical burden.

NCT ID: NCT00271843 Completed - Smoking Clinical Trials

Smoking and Alcohol Initiation

Start date: October 2005
Phase: Phase 1
Study type: Observational

This study evaluates multi-attribute utility, a modification of subjective expected utility, as a descriptive model of the adolescent's decision to initiate smoking or alcohol use. According to the model, the young decision maker envisions a set of consequences that will follow the two decision options, either to continue as a non-user or to initiate usage. Each consequence has three components. The components are the worth of the consequence, which may be positive or negative, the judged likelihood that the consequence will happen, and the importance of the consequence. Within an individual, importances will change with mood or circumstance, which is how the model accounts for impulsive decisions that may occur in social settings. The model will be tested by eliciting components of ten independent consequences from a large group of students early in the seventh-grade year. Current usage will also be examined; extant data suggest that most students will be non-users at that time. It is known that a fair amount of initiation takes place during the seventh and eighth grade years. The hypothesis is that those non-users whose model scores are high will be more likely to initiate usage than those whose scores are low. The same students will be queried regarding usage eighteen months later to evaluate the hypothesis. It is now well known that differential knowledge regarding the harmful effects of drug use does not distinguish adolescent users from non-users. The model approach quantifies the idea that anticipated positive consequences play a prominent role in the decision of those who choose to initiate. An important implication is that prevention campaigns might profit by addressing positive as well as negative consequences of usage.

NCT ID: NCT00271024 Completed - Smoking Cessation Clinical Trials

Efficacy of Naltrexone in Women's Smoking Cessation

Start date: December 2005
Phase: Phase 2
Study type: Interventional

The purpose of the proposed study is to conduct a randomized, double-blind clinical trial to compare adjunct treatment with 50 mg oral naltrexone vs. placebo in conjunction with standard smoking cessation treatment with nicotine patch and counseling. Hypotheses: 1. Naltrexone will improve smoking cessation quit rates, as measured at the end of active treatment (3 months) and during long term follow up (1 year). 2. Weight and smoking-related variables (i.e., less weight gain, as well as reduced craving and withdrawal) will be important factors by which naltrexone improves smoking cessation outcome. 3. These effects are predicted to be stronger in women compared to men.

NCT ID: NCT00265460 Completed - Smoking Clinical Trials

Smoking Cessation in Groups and With Tobacco Pastils

Start date: March 2005
Phase: Phase 2
Study type: Interventional

The purpose of this trial is to examine if smokeless tobacco combined with group support might increase smoking cessation rate compared with groups support in smokers.

NCT ID: NCT00261170 Completed - Smoking Clinical Trials

Bupropion for Hospital-Based Smoking Cessation

Start date: July 2003
Phase: Phase 3
Study type: Interventional

This is a randomized blinded trial of whether hospitalized smokers who are randomly assigned to receive bupropion, an antidepressant, and cognitive-behavioral counseling, are more likely to have quit smoking at the end of treatment and at 6 months compared with smokers randomly assigned to receive placebo and cognitive-behavioral counseling. Because depression is more prevalent among smokers and because smokers who are prone to depression may become depressed when they quit, the hypothesis is that the proportion of quitters who receive the active drug/antidepressant will be greater than the proportion of quitters who receive the placebo drug at 6 months.

NCT ID: NCT00253747 Completed - Smoking Clinical Trials

Smoking Cessation for Adults With Attention Deficit Hyperactivity Disorder (ADHD)

Start date: November 2005
Phase: Phase 3
Study type: Interventional

The objective of this study is to evaluate whether Osmotic-Release Methylphenidate (OROS MPH), relative to placebo, increases the effectiveness of standard smoking treatment (i.e., nicotine patch and individual smoking cessation counseling) in obtaining prolonged abstinence for smokers with Attention Deficit Hyperactivity Disorder (ADHD).

NCT ID: NCT00245323 Completed - Smoking Clinical Trials

Checking Smoking Status as a Routine Vital Sign: A Cluster-Randomized Trial of Its Effect on Cessation Counseling

Start date: November 2003
Phase: N/A
Study type: Interventional

The purpose of this study is to determine if checking smoking status as a routine vital sign increases the delivery rate of cessation counseling to adult smokers in primary care practices.

NCT ID: NCT00224185 Completed - Smoking Clinical Trials

Evaluation of Lungs of Normal Individuals by Lung Lavage, Brushing and Bronchial Wall Biopsy

Start date: January 2004
Phase: N/A
Study type: Observational

The purpose of this study is to obtain biologic materials from the blood and lungs of normal individuals to establish a set of normal range for various parameters. These will provide important information when applied to individuals with various pulmonary diseases, and will help in understanding of the etiology and pathogenesis of various lung diseases.

NCT ID: NCT00187603 Completed - Smoking Clinical Trials

Protecting the 'Hood Against Tobacco

Start date: July 2003
Phase: N/A
Study type: Interventional

Among all racial/ethnic groups, African Americans have the greatest risk of becoming ill or dying from tobacco-related diseases. Because of this disproportionate disease burden, it is particularly urgent that researchers focusing on tobacco control partner with African American communities. Intervention strategies which hold the tobacco industry accountable for its behavior are effective in changing views of tobacco use. In earlier work, the investigators found that information from internal tobacco industry documents, when shown to African American smokers, stimulated reflection about quitting and interest in disseminating information about industry targeting behaviors to others. However, to date there have been no attempts to utilize the information in industry documents as part of a smoking cessation intervention. In this project, the investigators will test whether a community co-developed, tailored quit-smoking program featuring exposures to African American-specific tobacco industry documents and media exercises in addition to proven individual quitting strategies can increase the number of people who quit smoking at six months and one year, as compared with usual care. The specific aims of the project are to: 1. test, using statistics, how well an innovative community-based, culturally tailored quit-smoking program for African Americans works at 6 and 12 months; 2. test selected variables for how well they predict who will return to smoking; 3. use interviews to identify additional individual and/or community factors associated with successful quitting or relapse; and 4. collect information to evaluate the overall effectiveness of the CARA project collaborative efforts in developing and sustaining the project over time, enhancing community awareness of tobacco issues, and creation or enhancement of community tobacco control resources.