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Smoking Cessation clinical trials

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NCT ID: NCT01925781 Terminated - Smoking Cessation Clinical Trials

e-Cigarettes Versus NRT Gum for Smoking Cessation

Start date: August 2013
Phase: Phase 4
Study type: Interventional

This is a randomized trial comparing electronic cigarettes (e-Cigarettes) to nicotine gum for smoking cessation. Participants will be randomly assigned to either e-cigarette use or nicotine gum use during a quit attempt. All participants will have a one hour meeting with a tobacco treatment specialist to develop a quit plan and set a quit date. Quit status will be determined at 12 weeks after the quit date. Continued use of nicotine replacement (either e-Cigarette or nicotine gum) and satisfaction with the treatment assignment will be evaluated.

NCT ID: NCT01850589 Terminated - Smoking Cessation Clinical Trials

Comparison of Conservative and Aggressive Smoking Cessation Treatment Strategies in a Vascular Surgery Office Practice

Start date: March 2011
Phase: N/A
Study type: Interventional

The aim of this study is to prove that the use of Bupropion with counseling works better than counseling alone for patients to quit smoking. The belief is that overall, there is a small percentage of patients who quit smoking all together.

NCT ID: NCT01842334 Terminated - Smoking Cessation Clinical Trials

D-cycloserine (DCS) Pretreatment + CBT + Nicotine Replacement Therapy for Smoking Cessation (DCS)

DCS
Start date: April 2013
Phase: Phase 1/Phase 2
Study type: Interventional

1. Compare the relative efficacy of ten weeks of once weekly 250 mg D-cycloserine (DCS) vs. placebo (both in conjunction with cognitive behavioral therapy (CBT) and nicotine replacement therapy (NRT) on reducing cigarette smoking in treatment-seeking nicotine-dependent outpatients. 2. Compare the relative efficacy of ten weeks of once weekly 250 mg DCS vs. placebo on the process of extinction and the memory encoding process.

NCT ID: NCT01761760 Terminated - Smoking Cessation Clinical Trials

Videogame-based Incentives for Smoking Cessation

Start date: May 8, 2017
Phase: N/A
Study type: Interventional

Investigators will be evaluating an online video-game-based smoking cessation intervention that will overcome barriers to treatment such as cost and sustainability. This videogame will be the first of its kind, based on an evidence-based intervention shown to promote smoking abstinence. The findings from this research will be of great public health significance because of the unprecedented reach and relatively low cost, as well as the potential for similar interventions to be developed for other health problems, such as alcohol or drug abuse and medication adherence for chronic illnesses

NCT ID: NCT01589211 Terminated - Smoking Cessation Clinical Trials

Brief Intervention Study for Quitting Smoking

BISQUITS
Start date: December 16, 2011
Phase: N/A
Study type: Interventional

To investigate the effectiveness of a smoking cessation intervention of two sessions (120 min at a time) in a group setting on the basis of Motivational Interviewing (MI) and important elements of Cognitive Behavioural Therapy (CBT). According to national and international guidelines patients are advised to quit and pharmacologically supported with one of the established first line smoking cessation treatments.

NCT ID: NCT01480232 Terminated - Smoking Cessation Clinical Trials

A Safety and Cognitive Function Study of EVP-6124 Versus Placebo in Subjects With Nicotine Dependence

Start date: December 2011
Phase: Phase 2
Study type: Interventional

This study is designed to evaluate the initial evidence for efficacy of the investigational medicine, EVP-6124, to improve smoking cessation outcomes with and without a standard taper of nicotine replacement therapy (NRT) in healthy nicotine dependent smokers

NCT ID: NCT01479998 Terminated - Smoking Cessation Clinical Trials

Novel Treatments to Enhance Smoking Cessation Before Cancer Surgery: Effects on Smoking and Surgical Outcomes

Start date: November 2011
Phase: Phase 1
Study type: Interventional

Eligible participants will be randomized to either: 1) standard care (i.e., 4 counseling sessions and nicotine replacement therapy (NRT)) or 2) standard care + contingency management (i.e., 4 counseling sessions and NRT + 3x/week meetings with positive reinforcers)

NCT ID: NCT01401569 Terminated - Depression Clinical Trials

Efficacy of Exercise and Counseling Intervention on Relapse in Smoker With Depressive Disorders

STOB-ACTIV
Start date: October 2010
Phase: Phase 3
Study type: Interventional

This study investigated the efficacy of an exercise and counseling intervention for depressed smokers (depression subscale of the Hospital Anxiety and Depression Scale, HADS-D score ≥ 8) in term of likelihood of smoking abstinence. Participants were randomized to 8 weeks of intervention: individually delivered exercise and counseling (for smoking cessation and physical activity) or control: health education contact control condition.

NCT ID: NCT00931021 Terminated - Smoking Cessation Clinical Trials

Smoking Cessation Treatment for Head and Neck Cancer Patients

Start date: July 2009
Phase: Phase 0
Study type: Interventional

This is a pilot research study examining the use of varenicline (Chantix) and the nicotine patch. The study is designed to find out whether one of these medications is more effective for smoking cessation with head and neck cancer patients. The study has three parts: 1) two intake sessions; 2) an 8-week treatment phase, and 3) a 3-month follow-up.

NCT ID: NCT00907218 Terminated - Smoking Cessation Clinical Trials

Chantix in Adult Smokers With Attention Deficit Hyperactivity Disorder (ADHD)

Start date: April 2009
Phase: Phase 4
Study type: Interventional

The purpose of this research study is to learn about the efficacy of a medication called varenicline (Chantix) in treating ADHD in adults and in reducing cigarette smoking in adults with ADHD. The investigators hypothesize that ADHD symptomatology in adults with ADHD will be improved with varenicline treatment. The investigators also hypothesize that varenicline treatment will result in significant reductions in cigarette smoking. Another objective of this study is to more fully evaluate the response and tolerability to varenicline in this group of cigarette smoking adults with ADHD.