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Smoking Cessation clinical trials

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NCT ID: NCT06148909 Not yet recruiting - Smoking Cessation Clinical Trials

Small Talk Intervention With MI for Smoking Cessation

Start date: December 1, 2023
Phase: N/A
Study type: Interventional

The goal of this pilot study is to examine the effectiveness of the STMI in promoting abstinence in unmotivated smokers. The main questions it aims to answer are: - Do unmotivated smokers treated with STMI exhibit higher abstinence rate than those in the control group? - Do unmotivated smokers treated with STMI show higher intention to quit than those in the control group? - Do unmotivated smokers treated with STMI show higher smoking reduction rates than those in the control group? - Do unmotivated smokers treated with STMI show lower level of depressive symptoms than those in the control group? - Do unmotivated smokers treated with STMI show higher adherence than those in the control group? - Does STMI show higher consent rates than those the control? - How does STMI affect the smoking behaviors in unmotivated smokers? Participants will be randomized to (1) STMI or (2) control group for smoking cessation services via telephone, and then be invited to join a semi-structured interview.

NCT ID: NCT06145685 Completed - Smoking Cessation Clinical Trials

Effect of Smoking Cessation on Salivary IL-1β and PGE-2 Levels Following Non-Surgical Periodontal Therapy

Start date: January 1, 2021
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate the effect of smoking cessation on inflammatory markers following non-surgical treatment of periodontal disease. This is to assess the period of smoking abstinence needed before any periodontal surgery in order to reverse the negative effects of the reported increased levels of inflammatory markers (IL-1β and PGE2 in this study) associated with smoking on the healing and the periodontium.

NCT ID: NCT06130423 Recruiting - Smoking Cessation Clinical Trials

Study to Evaluate Music Therapy and Nicotine Replacement Therapy on Craving Related to Smoking Cessation in Health Staff

MUSMOKHEALTH
Start date: February 28, 2024
Phase: N/A
Study type: Interventional

The study is a randomized, controlled trial comparing music therapy associated to NRT versus NRT alone to evaluate the value of music therapy in improving the management of craving among 50 health staff smokers. This pilot multi-method study will combine the methodology of clinical trial with qualitative techniques used in social sciences to show the interest of a digital music therapy tool, adapted to a health staff audience.

NCT ID: NCT06127589 Recruiting - Smoking Cessation Clinical Trials

The "Quit-for-Kids" Project: to Increase Abstinence and Protect Children From Tobacco Smoke Exposure

Start date: February 5, 2024
Phase: N/A
Study type: Interventional

This project aims to test the effectiveness of an integrated intervention of brief cessation advice (AWARD), Nicotine Replacement Therapy, and Instant Messaging support compared with waitlist control participants among adult daily smokers who lived with their children and non-smoking partners.

NCT ID: NCT06111755 Recruiting - Smoking Cessation Clinical Trials

Quit Smoking Text Message Study

Start date: March 26, 2024
Phase: N/A
Study type: Interventional

This project will address research gaps and advance the science of smoking cessation by conducting a randomized controlled trial of an evidence-based, population-level quit smoking text messaging program with or without a smartband.

NCT ID: NCT06111053 Recruiting - Obesity Clinical Trials

Trial for Harm Reduction With Incentives & Vaping E-cigarettes

THRIVE
Start date: October 2, 2023
Phase: N/A
Study type: Interventional

The purpose of this study is to provide preliminary information on the effect of electronic nicotine delivery systems (ENDS) provisions and contingent incentives (CI) on smoking in individuals with overweight/obesity who smoke cigarettes (SWO). All participants will be provided information on the comparative risk of ENDS relative to cigarette smoking, and a randomized group of participants will be provided ENDS provisions for 6 weeks. All participants will complete breath samples for 28 days to measure their exhaled carbon monoxide and will either receive fixed incentives for sample completion or receive varying incentives contingent on their carbon monoxide levels. Researchers will compare groups to understand the effect of each condition on smoking-related behavior.

NCT ID: NCT06098144 Recruiting - Smoking Cessation Clinical Trials

Smoking Cessation Program in the Construction Sector

Start date: April 10, 2024
Phase: Phase 4
Study type: Interventional

The main objective of this study is to identify the optimal adaptive smoking cessation program for the construction sector in terms of effectiveness, cost-effectiveness, and potential implementation.

NCT ID: NCT06091826 Completed - Smoking Cessation Clinical Trials

Study Assessing Efficacy and Safety of NFL-101 on Reduction of Reinforcing Properties of Cigarettes (PRECESTO)

PRECESTO
Start date: February 21, 2023
Phase: Phase 2
Study type: Interventional

PRECESTO is a randomized, double-blind, cross-over trial on 34 smokers who do not want to stop smoking and get high satisfaction from smoking. The primary objective is to assess efficacy of NFL-101 in reducing the positive reinforcing properties of cigarettes compared to placebo measured by the modified Cigarette Evaluation Questionnaire (mCEQ) "Smoking Satisfaction" (items 1, 2, and 12) subscale.

NCT ID: NCT06088862 Active, not recruiting - Smoking Cessation Clinical Trials

Evaluate Harm Reduction Products as a Second Line Intervention for Adult Smokers Who Do Not Quit With NRT

Start date: December 27, 2023
Phase: Phase 3
Study type: Interventional

This study will determine whether a range of products along the reduced-risk continuum can reduce smoke exposure for individuals who fail to quit smoking using current medically approved nicotine replacement therapy (NRT) products. The strategy will be to offer 325 smokers four weeks of NRT of their choice (gum, lozenge, or nicotine patch) and assess them for quit-smoking status at the end of the period. Seven-day point abstinence will be used to determine responder status at the end of the four-week period (CO of <6 ppm at both CO collection points during that seven-day period and self-report of no smoking during that seven-day period). Those who have not quit, and who therefore have a very low chance of later success (a consistent finding in prior studies and to be verified in the proposed study), will be randomly assigned to either receive a potential "rescue" product (nicotine pouch or ENDS (electronic nicotine delivery system), or remain on NRT (control group).

NCT ID: NCT06087328 Recruiting - Smoking Cessation Clinical Trials

CAN-DOSE Study: Cessation With Augmented Nicotine for Dual Use Of Smoking and E-cigarettes

CAN-DOSE
Start date: December 5, 2023
Phase: Phase 2
Study type: Interventional

Many people smoke cigarettes and use e-cigarettes, and have a hard time stopping. Nicotine replacement therapy medications, such as nicotine patches and lozenges, have been shown to help people quit e-cigarette use. The purpose of the present study is to see how well nicotine patches and lozenges help people quit both smoking and vaping, and to determine if higher doses of the medication work best.